Eicosapentaenoic acid attenuates progression of hepatic fibrosis with inhibition of reactive oxygen species production in rats fed methionine- and choline-deficient diet

scientific article published on 17 September 2010

Eicosapentaenoic acid attenuates progression of hepatic fibrosis with inhibition of reactive oxygen species production in rats fed methionine- and choline-deficient diet is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1024589881
P356DOI10.1007/S10620-010-1400-5
P2888exact matchhttps://scigraph.springernature.com/pub.10.1007/s10620-010-1400-5
P698PubMed publication ID20848203

P2093author name stringTakashi Takeuchi
Kazunori Imada
Yutaka Shimizu
Akiko Kawashima
Kiyoshi Mizuguchi
Tsuyoshi Harada
Satoshi Kajikawa
P2860cites workCharacterization of pathogenic and prognostic factors of nonalcoholic steatohepatitis associated with obesityQ73246068
Serum thioredoxin levels as a predictor of steatohepatitis in patients with nonalcoholic fatty liver diseaseQ78654225
Systemic inflammation in nonalcoholic fatty liver disease is characterized by elevated levels of CCL2Q83161496
Polyunsaturated fatty acids stimulate hepatic UCP-2 expression via a PPARalpha-mediated pathwayQ28191448
Activation of hepatic stellate cells by TGF alpha and collagen type I is mediated by oxidative stress through c-myb expressionQ28367828
Involvement of reactive oxygen species and nitric oxide radicals in activation and proliferation of rat hepatic stellate cellsQ31906559
Nonalcoholic steatosis and steatohepatitis. I. Molecular mechanism for polyunsaturated fatty acid regulation of gene transcriptionQ34369949
Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysisQ34578231
Pathogenesis and management issues for non-alcoholic fatty liver diseaseQ36179902
Mitochondrial dysfunction in NASH: causes, consequences and possible means to prevent it.Q36365999
n-3 fatty acids and the metabolic syndromeQ36536076
Suppression of hepatic fat accumulation by highly purified eicosapentaenoic acid prevents the progression of d-galactosamine-induced hepatitis in mice fed with a high-fat/high-sucrose dietQ38354453
Highly purified eicosapentaenoic acid prevents the progression of hepatic steatosis by repressing monounsaturated fatty acid synthesis in high-fat/high-sucrose diet-fed miceQ38355498
4-Hydroxynonenal as a selective pro-fibrogenic stimulus for activated human hepatic stellate cellsQ42454202
In contrast with docosahexaenoic acid, eicosapentaenoic acid and hypolipidaemic derivatives decrease hepatic synthesis and secretion of triacylglycerol by decreased diacylglycerol acyltransferase activity and stimulation of fatty acid oxidation.Q42994685
Protective effects of eicosapentaenoic acid on genotoxicity and oxidative stress of cyclophosphamide in miceQ43201528
Activity of the leukocyte NADPH oxidase in whole neutrophils and cell-free neutrophil preparations stimulated with long-chain polyunsaturated fatty acidsQ43568775
Fish oil feeding alters liver gene expressions to defend against PPARalpha activation and ROS productionQ43862660
In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver diseasesQ44036833
Polyunsaturated fatty acids as antioxidants.Q44692726
Oxidative stress and enzymatic antioxidant status in patients with nonalcoholic steatohepatitisQ44810635
Effects of n-3 polyunsaturated fatty acids in subjects with nonalcoholic fatty liver diseaseQ46869764
Prolonged n-3 polyunsaturated fatty acid supplementation ameliorates hepatic steatosis in patients with non-alcoholic fatty liver disease: a pilot study.Q51500156
P433issue4
P921main subjectreactive oxygen speciesQ424361
P304page(s)1065-1074
P577publication date2010-09-17
P1433published inDigestive Diseases and SciencesQ15716711
P1476titleEicosapentaenoic acid attenuates progression of hepatic fibrosis with inhibition of reactive oxygen species production in rats fed methionine- and choline-deficient diet
P478volume56

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cites work (P2860)
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Q37017917Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.
Q36524312Efficacy of alogliptin in preventing non-alcoholic fatty liver disease progression in patients with type 2 diabetes
Q35588868Eicosapentaenoic acid ameliorates non-alcoholic steatohepatitis in a novel mouse model using melanocortin 4 receptor-deficient mice
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Q41102448Long-Term Administration of Eicosapentaenoic Acid Improves Post-Myocardial Infarction Cardiac Remodeling in Mice by Regulating Macrophage Polarization
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Q34760318Omega-3 polyunsaturated fatty acid and ursodeoxycholic acid have an additive effect in attenuating diet-induced nonalcoholic steatohepatitis in mice
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Q37111117ω-3 PUFAs ameliorate liver fibrosis and inhibit hepatic stellate cells proliferation and activation by promoting YAP/TAZ degradation.

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