Heterogeneity and chronology of PTEN deletion and ERG fusion in prostate cancer

scientific article published on 25 April 2014

Heterogeneity and chronology of PTEN deletion and ERG fusion in prostate cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/MODPATHOL.2014.70
P698PubMed publication ID24762546

P50authorPierre TennstedtQ40045926
P2093author name stringGuido Sauter
Ronald Simon
Markus Graefen
Sarah Minner
Thorsten Schlomm
Martina Kluth
Stefan Steurer
Antje Krohn
Fabian Freudenthaler
Melanie Bauer
Lia Burkhardt
Silvia Harasimowicz
Sarah Fuchs
Maria C Tsourlakis
Phillip Stahl
Hueseyin Sirma
P2860cites workThe genomic complexity of primary human prostate cancerQ24617949
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesisQ24681977
FISH analysis of 107 prostate cancers shows that PTEN genomic deletion is associated with poor clinical outcome.Q27851411
Cancer statistics, 2010Q27860525
Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion SequencingQ27860948
Oncogene-mediated alterations in chromatin conformationQ36061468
Killin is a p53-regulated nuclear inhibitor of DNA synthesisQ36535351
Distinct genomic aberrations associated with ERG rearranged prostate cancerQ37173727
Fluorescence in situ hybridization study shows association of PTEN deletion with ERG rearrangement during prostate cancer progressionQ37383459
ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy.Q39500478
Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostateQ39506775
Mutation and expression analysis of the putative prostate tumour-suppressor gene PTENQ39711051
Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesisQ41778982
PTEN genomic deletion is an early event associated with ERG gene rearrangements in prostate cancerQ42473567
Is PTEN loss associated with clinical outcome measures in human prostate cancer?Q43249619
Morphologic and clinical significance of multifocal prostate cancers in radical prostatectomy specimensQ43864003
Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancerQ45017329
PTEN genomic deletion is associated with p-Akt and AR signalling in poorer outcome, hormone refractory prostate cancerQ47919199
Novel, gross chromosomal alterations involving PTEN cooperate with allelic loss in prostate cancer.Q52623792
Genomic Deletion of PTEN Is Associated with Tumor Progression and Early PSA Recurrence in ERG Fusion-Positive and Fusion-Negative Prostate CancerQ57782669
Absence of TMPRSS2:ERG fusions and PTEN losses in prostate cancer is associated with a favorable outcomeQ57790493
ThePTEN gene in locally progressive prostate cancer is preferentially inactivated by bi-allelic gene deletionQ63966367
Marked heterogeneity of ERG expression in large primary prostate cancersQ84814749
P433issue12
P921main subjectprostate cancerQ181257
P304page(s)1612-1620
P577publication date2014-04-25
P1433published inModern PathologyQ15724578
P1476titleHeterogeneity and chronology of PTEN deletion and ERG fusion in prostate cancer
P478volume27