Improved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis

scientific article published on 28 July 2016

Improved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis is …
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scholarly articleQ13442814

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P356DOI10.1007/S10067-016-3363-1
P698PubMed publication ID27470088

P2093author name stringNathawut Sibmooh
Supeenun Unchern
Nadhaporn Saengpetch
Thitima Kasemsuk
P2860cites workBromelain as a Treatment for Osteoarthritis: a Review of Clinical StudiesQ24558705
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Is the placebo powerless? An analysis of clinical trials comparing placebo with no treatmentQ33948133
Nonsteroidal anti-inflammatory drug-associated dyspepsia: the scale of the problemQ34134268
Bromelain reduces mild acute knee pain and improves well-being in a dose-dependent fashion in an open study of otherwise healthy adultsQ34177340
Using Effect Size-or Why the P Value Is Not EnoughQ34368143
Efficacy and tolerability of oral enzyme therapy as compared to diclofenac in active osteoarthrosis of knee joint: an open randomized controlled clinical trialQ34518095
Endogenous production of reactive oxygen species is required for stimulation of human articular chondrocyte matrix metalloproteinase production by fibronectin fragmentsQ35842797
The measurement of blood and plasma nitrite by chemiluminescence: pitfalls and solutions.Q36545307
Effects of flurbiprofen and tiaprofenic Acid on oxidative stress markers in osteoarthritis: A prospective, randomized, open-label, active- and placebo-controlled trialQ37661071
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Bromelain inhibits lipopolysaccharide-induced cytokine production in human THP-1 monocytes via the removal of CD14.Q39969916
Bacoside A and bromelain relieve dichlorvos induced changes in oxidative responses in mice serumQ42697139
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Synovial tissue inflammation in early and late osteoarthritisQ43048512
Cyclooxygenase-2 expression in lipopolysaccharide-stimulated human monocytes is modulated by cyclic AMP, prostaglandin E(2), and nonsteroidal anti-inflammatory drugsQ43510686
Placebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration - new evidence on the antiinflammatory mode of action of bromelain.Q43602017
Determination of the eicosanoid response to inflammatory stimuli in whole blood and its pharmacological modulation ex vivoQ44473374
Reporting of noninferiority and equivalence randomized trials: extension of the CONSORT 2010 statementQ46597529
The presence of molecular markers of in vivo lipid peroxidation in osteoarthritic cartilage: a pathogenic role in osteoarthritisQ46689837
Production of lipid peroxidation products in osteoarthritic tissues: new evidence linking 4-hydroxynonenal to cartilage degradationQ46873003
Perioperative bromelain reduces pain and swelling and improves quality of life measures after mandibular third molar surgery: a randomized, double-blind, placebo-controlled clinical trialQ47904417
[Drug therapy of activated arthrosis. On the effectiveness of an enzyme mixture versus diclofenac]Q51000179
Bromelain as an adjunctive treatment for moderate-to-severe osteoarthritis of the knee: a randomized placebo-controlled pilot studyQ59569150
Determination of alpha-tocopherol in tissues and plasma by high-performance liquid chromatographyQ71784004
BROMELAINS THERAPY IN RHEUMATOID ARTHRITISQ76861127
Improved method for the determination of blood glutathioneQ79579725
Synthesis and release of human cartilage matrix proteoglycans are differently regulated by nitric oxide and prostaglandin-E2Q80280379
P433issue10
P921main subjectosteoarthritisQ62736
knee osteoarthritisQ1777118
P304page(s)2531-2540
P577publication date2016-07-28
P1433published inClinical RheumatologyQ15754927
P1476titleImproved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis
P478volume35

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Q49922324Osteoarthritis year in review 2017: clinical.cites workP2860

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