scholarly article | Q13442814 |
P50 | author | Brittany G Durgin | Q87833296 |
P2093 | author name string | Adam C Straub | |
Katherine C Wood | |||
Subramaniam Sanker | |||
Rohan C Shah | |||
P2860 | cites work | Soluble guanylate cyclase activation by nitric oxide and its reversal. Involvement of sulfhydryl group oxidation and reduction | Q72550210 |
Functions of conserved cysteines of soluble guanylyl cyclase | Q73139586 | ||
A point-mutated guanylyl cyclase with features of the YC-1-stimulated enzyme: implications for the YC-1 binding site? | Q73187839 | ||
NADPH and heme redox modulate pulmonary artery relaxation and guanylate cyclase activation by NO | Q73279048 | ||
Protoporphyrin IX generation from delta-aminolevulinic acid elicits pulmonary artery relaxation and soluble guanylate cyclase activation | Q80088112 | ||
Nitric oxide- and heme-independent activation of soluble guanylate cyclase attenuates peroxynitrite-induced endothelial dysfunction in rat aorta | Q84853346 | ||
Effects of peroxynitrite on relaxation through the NO/sGC/cGMP pathway in isolated rat iliac arteries | Q86625658 | ||
Crystal structures of the catalytic domain of human soluble guanylate cyclase | Q24336722 | ||
NO-independent regulatory site of direct sGC stimulators like YC-1 and BAY 41-2272 | Q24798007 | ||
The basics of thiols and cysteines in redox biology and chemistry | Q26991843 | ||
NO and CO differentially activate soluble guanylyl cyclase via a heme pivot-bend mechanism | Q27641107 | ||
Crystal structure of the guanylyl cyclase Cya2 | Q27652450 | ||
The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase | Q27652454 | ||
Crystal structure of the signaling helix coiled-coil domain of the β1 subunit of the soluble guanylyl cyclase | Q27659219 | ||
Structural and Functional Evidence Indicates Selective Oxygen Signaling in Caldanaerobacter subterraneus H-NOX | Q27712655 | ||
Structure of the adenylyl cyclase catalytic core | Q27735000 | ||
Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS | Q27748762 | ||
Novel complexes of guanylate cyclase with heat shock protein 90 and nitric oxide synthase | Q28188797 | ||
AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase | Q28283420 | ||
Characterization of NS 2028 as a specific inhibitor of soluble guanylyl cyclase | Q28379365 | ||
Sensitizing soluble guanylyl cyclase to become a highly CO-sensitive enzyme | Q28379416 | ||
Spare guanylyl cyclase NO receptors ensure high NO sensitivity in the vascular system | Q28513504 | ||
Anti-peroxynitrite treatment ameliorated vasorelaxation of resistance arteries in aging rats: involvement with NO-sGC-cGKs pathway | Q28541815 | ||
Guanylyl cyclase/PSD-95 interaction: targeting of the nitric oxide-sensitive alpha2beta1 guanylyl cyclase to synaptic membranes | Q28565964 | ||
Soluble guanylate cyclase stimulation prevents fibrotic tissue remodeling and improves survival in salt-sensitive Dahl rats | Q28742463 | ||
Thiol chemistry and specificity in redox signaling | Q29615000 | ||
Cysteine function governs its conservation and degeneration and restricts its utilization on protein surfaces | Q30394922 | ||
Nitric oxide activates guanylate cyclase and increases guanosine 3′:5′-cyclic monophosphate levels in various tissue preparations | Q30449094 | ||
NO-independent regulatory site on soluble guanylate cyclase | Q32165040 | ||
Downregulation of soluble guanylyl cyclase in young and aging spontaneously hypertensive rats | Q33178899 | ||
Characterization of a novel type of endogenous activator of soluble guanylyl cyclase | Q33208407 | ||
The signaling helix: a common functional theme in diverse signaling proteins | Q33256438 | ||
Tissue distribution of the human soluble guanylate cyclases | Q33876232 | ||
YC-1 activation of human soluble guanylyl cyclase has both heme-dependent and heme-independent components | Q33948966 | ||
The fibrate gemfibrozil is a NO- and haem-independent activator of soluble guanylyl cyclase: in vitro studies | Q34042836 | ||
Nitric oxide and heat shock protein 90 activate soluble guanylate cyclase by driving rapid change in its subunit interactions and heme content. | Q34075870 | ||
Effects of thiol inhibitors on hepatic guanylate cylase activity | Q39195101 | ||
Restoration of the responsiveness of purified guanylate cyclase to nitrosoguanidine, nitric oxide, and related activators by heme and hemeproteins. Evidence for involvement of the paramagnetic nitrosyl-heme complex in enzyme activation | Q39218847 | ||
Heme oxygenase-1 induction depletes heme and attenuates pulmonary artery relaxation and guanylate cyclase activation by nitric oxide | Q39624782 | ||
Acrylamide analog as a novel nitric oxide-independent soluble guanylyl cyclase activator | Q40218170 | ||
Effects of cyclic GMP on smooth muscle relaxation. | Q40624466 | ||
Heat shock protein 90 regulates stabilization rather than activation of soluble guanylate cyclase | Q42030989 | ||
A-350619: a novel activator of soluble guanylyl cyclase | Q42049434 | ||
Regulation of soluble guanylyl cyclase redox state by hydrogen sulfide | Q42361109 | ||
Effect of YC-1, an NO-independent, superoxide-sensitive stimulator of soluble guanylyl cyclase, on smooth muscle responsiveness to nitrovasodilators | Q42435281 | ||
Protein kinase G phosphorylates soluble guanylyl cyclase on serine 64 and inhibits its activity. | Q42439086 | ||
Activation of soluble guanylate cyclase by carbon monoxide and inhibition by superoxide anion | Q42474950 | ||
Guanylyl cyclase sensitivity to nitric oxide is protected by a thiol oxidation-driven interaction with thioredoxin-1. | Q42511668 | ||
Biliverdin IX is an endogenous inhibitor of soluble guanylyl cyclase. | Q42523405 | ||
Discovery of IWP-051, a Novel Orally Bioavailable sGC Stimulator with Once-Daily Dosing Potential in Humans | Q42787506 | ||
Smooth muscle-specific deletion of nitric oxide-sensitive guanylyl cyclase is sufficient to induce hypertension in mice | Q43197344 | ||
The soluble guanylyl cyclase inhibitor NS-2028 reduces vascular endothelial growth factor-induced angiogenesis and permeability | Q43209084 | ||
Calcium-dependent membrane association sensitizes soluble guanylyl cyclase to nitric oxide | Q43911622 | ||
Endogenous carbon monoxide is an endothelial-derived vasodilator factor in the mesenteric circulation | Q44225851 | ||
Induction of heme oxygenase-1 and stimulation of cGMP production by hemin in aortic tissues from hypertensive rats | Q44265476 | ||
Cytochrome b5 Reductase 3 Modulates Soluble Guanylate Cyclase Redox State and cGMP Signaling | Q45060738 | ||
Soluble guanylyl cyclase activation by HMR-1766 (ataciguat) in cells exposed to oxidative stress | Q46403664 | ||
Effects of hydrogen peroxide on relaxation through the NO/sGC/cGMP pathway in isolated rat iliac arteries | Q46675366 | ||
Structure and monomer/dimer equilibrium for the guanylyl cyclase domain of the optogenetics protein RhoGC. | Q47423710 | ||
Exchange of substrate and inhibitor specificities between adenylyl and guanylyl cyclases | Q47954577 | ||
Site-Specific Phosphorylation of PSD-95 PDZ Domains Reveals Fine-Tuned Regulation of Protein-Protein Interactions | Q48203496 | ||
Discovery of the Soluble Guanylate Cyclase Stimulator Vericiguat (BAY 1021189) for the Treatment of Chronic Heart Failure. | Q48358311 | ||
Carbon monoxide: an endogenous modulator of the nitric oxide-cyclic GMP signaling system. | Q49047336 | ||
The deactivation of soluble guanylyl cyclase by redox-active agents. | Q50525208 | ||
Neuronal nitric oxide synthase localizes to utrophin expressing intercalated discs and stabilizes their structural integrity. | Q52664646 | ||
Nitric Oxide-Independent Soluble Guanylate Cyclase Activation Improves Vascular Function and Cardiac Remodeling in Sickle Cell Disease. | Q52738823 | ||
A heme oxygenase product, presumably carbon monoxide, mediates a vasodepressor function in rats. | Q54180770 | ||
Different influences of extracellular and intracellular superoxide on relaxation through the NO/sGC/cGMP pathway in isolated rat iliac arteries. | Q54314594 | ||
Characterization of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one as a heme-site inhibitor of nitric oxide-sensitive guanylyl cyclase | Q71239563 | ||
Reversible inactivation of guanylate cyclase by mixed disulfide formation | Q72457078 | ||
Heme oxygenase-1 deficiency leads to alteration of soluble guanylate cyclase redox regulation | Q34214656 | ||
Pressure-overload-induced subcellular relocalization/oxidation of soluble guanylyl cyclase in the heart modulates enzyme stimulation | Q34686759 | ||
Pulmonary and systemic vasodilator responses to the soluble guanylyl cyclase activator, BAY 60-2770, are not dependent on endogenous nitric oxide or reduced heme | Q34720361 | ||
Clinically important features of porphyrin and heme metabolism and the porphyrias | Q34785744 | ||
Discovery of riociguat (BAY 63-2521): a potent, oral stimulator of soluble guanylate cyclase for the treatment of pulmonary hypertension | Q34957241 | ||
Structure and signaling mechanism of Per-ARNT-Sim domains | Q35008317 | ||
Targeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vessels | Q35009484 | ||
Cardiovascular actions of a novel NO-independent guanylyl cyclase stimulator, BAY 41-8543: in vivo studies | Q35044037 | ||
Pharmacological actions of a novel NO-independent guanylyl cyclase stimulator, BAY 41-8543: in vitro studies | Q35044042 | ||
NO- and haem-independent activation of soluble guanylyl cyclase: molecular basis and cardiovascular implications of a new pharmacological principle | Q35044464 | ||
Mutation of His-105 in the beta 1 subunit yields a nitric oxide-insensitive form of soluble guanylyl cyclase | Q35124292 | ||
Fatal gastrointestinal obstruction and hypertension in mice lacking nitric oxide-sensitive guanylyl cyclase | Q35778348 | ||
Desensitization of soluble guanylyl cyclase, the NO receptor, by S-nitrosylation | Q35925811 | ||
Soluble guanylyl cyclase requires heat shock protein 90 for heme insertion during maturation of the NO-active enzyme | Q36167665 | ||
The soluble guanylyl cyclase activator bay 58-2667 selectively limits cardiomyocyte hypertrophy | Q36380981 | ||
Heme-assisted S-nitrosation desensitizes ferric soluble guanylate cyclase to nitric oxide | Q36466804 | ||
Chronic β1-adrenergic blockade enhances myocardial β3-adrenergic coupling with nitric oxide-cGMP signaling in a canine model of chronic volume overload: new insight into mechanisms of cardiac benefit with selective β1-blocker therapy. | Q36629698 | ||
Molecular model of a soluble guanylyl cyclase fragment determined by small-angle X-ray scattering and chemical cross-linking | Q36713981 | ||
S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds | Q36780079 | ||
Soluble guanylate cyclase as an alternative target for bronchodilator therapy in asthma | Q36865999 | ||
Characterization of functional heme domains from soluble guanylate cyclase | Q36947015 | ||
Redox regulation in the extracellular environment | Q37045097 | ||
Potential role of mitochondrial superoxide decreasing ferrochelatase and heme in coronary artery soluble guanylate cyclase depletion by angiotensin II. | Q37071925 | ||
S-nitrosylation of tissue-type plasminogen activator confers vasodilatory and antiplatelet properties on the enzyme | Q37178111 | ||
Soluble guanylate cyclase redox state under oxidative stress conditions in isolated monkey coronary arteries | Q37303013 | ||
Cinaciguat, a soluble guanylate cyclase activator, causes potent and sustained pulmonary vasodilation in the ovine fetus | Q37343908 | ||
Crystal structure of an oxygen-binding heme domain related to soluble guanylate cyclases | Q37511692 | ||
YC-1 binding to the β subunit of soluble guanylyl cyclase overcomes allosteric inhibition by the α subunit. | Q37557818 | ||
Thiol-Based Redox Modulation of Soluble Guanylyl Cyclase, the Nitric Oxide Receptor | Q37588783 | ||
The G-protein regulator LGN modulates the activity of the NO receptor soluble guanylate cyclase | Q37598759 | ||
Single-particle EM reveals the higher-order domain architecture of soluble guanylate cyclase | Q37612777 | ||
Nitric oxide-induced conformational changes in soluble guanylate cyclase | Q37727207 | ||
Structure and regulation of soluble guanylate cyclase | Q37992160 | ||
Structure and Activation of Soluble Guanylyl Cyclase, the Nitric Oxide Sensor | Q38894826 | ||
Tipping off endothelial tubes: nitric oxide drives tip cells | Q38928432 | ||
P304 | page(s) | 97-104 | |
P577 | publication date | 2018-03-22 | |
P1433 | published in | Nitric Oxide | Q7041392 |
P1476 | title | Redox regulation of soluble guanylyl cyclase | |
P478 | volume | 76 |
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