Metabolic syndrome and the decreased levels of uric acid by leflunomide favor redox imbalance in patients with rheumatoid arthritis

scientific article published on 11 April 2018

Metabolic syndrome and the decreased levels of uric acid by leflunomide favor redox imbalance in patients with rheumatoid arthritis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S10238-018-0500-Y
P698PubMed publication ID29644482

P50authorMichael MaesQ30504745
Andréa Name Colado SimãoQ88336514
P2093author name stringDaniela Frizon Alfieri
Edna Maria Vissoci Reiche
Isaias Dichi
Marcell Alysson Batisti Lozovoy
Bruna Miglioranza Scavuzzi
Neide Tomimura Costa
Bruno Alexandre Sekiguchi
Fabiano Aparecido de Medeiros
Marcelo Cândido de Sá
Tatiana Mayumi Veiga Iriyoda
Pâmela Lonardoni Micheletti
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Uric acid is a strong independent predictor of renal dysfunction in patients with rheumatoid arthritisQ37350911
Benefit-risk assessment of leflunomide: an appraisal of leflunomide in rheumatoid arthritis 10 years after licensingQ37633519
The active metabolite of leflunomide, A77 1726, attenuates inflammatory arthritis in mice with spontaneous arthritis via induction of heme oxygenase-1.Q37638284
Uric acid and hypertension: cause or effect?Q37738112
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Uric acid stimulates monocyte chemoattractant protein-1 production in vascular smooth muscle cells via mitogen-activated protein kinase and cyclooxygenase-2.Q44438488
Nitric oxide production of T lymphocytes is increased in rheumatoid arthritis.Q44706589
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Assessment of ischemia-modified albumin levels in patients with rheumatoid arthritis.Q46867303
Identification of clinical parameters associated with serum oxidative stress in patients with rheumatoid arthritisQ46914146
Metabolic syndrome prevalence is increased in rheumatoid arthritis patients and is associated with disease activity.Q50957777
Advanced oxidation protein products are more related to metabolic syndrome components than biomarkers of lipid peroxidation.Q51298846
Infliximab is equivalently suppressing oxidative stress compared to tocilizumab among well-controlled patients with rheumatoid arthritis.Q51364675
The hypouricemiant effect of leflunomide.Q54513719
Correlation between blood antioxidant levels and lipid peroxidation in rheumatoid arthritisQ55067101
2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiativeQ56506042
Influence of leflunomide on renal handling of urate and phosphate in patients with rheumatoid arthritisQ57076798
Nitric oxide is a mediator of apoptosis in the rheumatoid jointQ57534159
Visceral Fat Adipokine Secretion Is Associated With Systemic Inflammation in Obese HumansQ63866263
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An experimental model for hydrogen peroxide-induced tissue damage. Effects of a single inflammatory mediator on (peri)articular tissuesQ69506389
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Oxidative stress in blood of HIV infected patientsQ71820673
Oxidative damage to proteins: spectrophotometric method for carbonyl assayQ72024490
Levels of plasma lipid peroxide products and antioxidant status in rheumatoid arthritisQ73321276
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Association of serum uric acid with cardiovascular disease in rheumatoid arthritisQ80651977
Etanercept reduces the oxidative stress marker levels in patients with rheumatoid arthritisQ80695386
Uric acid and cardiovascular risk in rheumatoid arthritisQ82655937
Paraoxonase and arylesterase levels in rheumatoid arthritisQ83208416
No impact of serum uric acid on the outcome of recent-onset arthritisQ83729866
Serum protein oxidation in patients with rheumatoid arthritis and effects of infliximab therapyQ83823925
Oxidative stress is associated with liver damage, inflammatory status, and corticosteroid therapy in patients with systemic lupus erythematosusQ84669486
The onset of lipid peroxidation in rheumatoid arthritis: consequences and monitoringQ87075616
Plasma glutathione peroxidase (GSH-Px) concentration is elevated in rheumatoid arthritis: a case-control studyQ87376514
Association between serum uric acid and inflammation in rheumatoid arthritis: perspective on lowering serum uric acid of leflunomideQ87534867
Albumin and Protein Oxidation are Predictors that Differentiate Relapsing-Remitting from Progressive Clinical Forms of Multiple SclerosisQ89083185
P433issue3
P921main subjectrheumatoid arthritisQ187255
metabolic syndromeQ657193
P304page(s)363-372
P577publication date2018-04-11
P1433published inClinical and Experimental MedicineQ15753118
P1476titleMetabolic syndrome and the decreased levels of uric acid by leflunomide favor redox imbalance in patients with rheumatoid arthritis
P478volume18

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Q89669659Spectrum and prognosis of renal histopathological lesions in 56 Chinese patients with rheumatoid arthritis with renal involvementcites workP2860

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