Modulation of LIN28B/Let-7 Signaling by Propranolol Contributes to Infantile Hemangioma Involution

scientific article published on 03 May 2018

Modulation of LIN28B/Let-7 Signaling by Propranolol Contributes to Infantile Hemangioma Involution is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1161/ATVBAHA.118.310908
P932PMC publication ID5970092
P698PubMed publication ID29724816

P50authorHana Totary-JainQ59822495
John H LockhartQ86775341
P2093author name stringThomas Tuschl
June K Wu
Ezinne Francess Mong
Jeffrey VanWye
John Canfield
John C M Tsibris
Kemal Marc Akat
Andrew Matar
P2860cites workHydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brainQ24299862
TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylationQ24308810
Lin28 mediates the terminal uridylation of let-7 precursor MicroRNAQ24308839
A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitmentQ24310207
Evidence by molecular profiling for a placental origin of infantile hemangiomaQ24535837
Selective blockade of microRNA processing by Lin28Q24609864
The basics of epithelial-mesenchymal transitionQ24652992
Induced pluripotent stem cell lines derived from human somatic cellsQ27860597
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factorsQ27860937
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegansQ27861103
GLUT1: a newly discovered immunohistochemical marker for juvenile hemangiomasQ28144358
Identification of hundreds of conserved and nonconserved human microRNAsQ28257480
Lin28: primal regulator of growth and metabolism in stem cellsQ28288454
Quantitative analysis of histological staining and fluorescence using ImageJQ28364633
STAR: ultrafast universal RNA-seq alignerQ29615052
RNA polymerase III transcribes human microRNAsQ29618698
Infantile Hemangioma Originates From A Dysregulated But Not Fully Transformed Multipotent Stem Cell.Q30826592
MicroRNA discovery and profiling in human embryonic stem cells by deep sequencing of small RNA librariesQ33347079
N-Myc regulates expression of pluripotency genes in neuroblastoma including lif, klf2, klf4, and lin28bQ33460427
The two stem cell microRNA gene clusters C19MC and miR-371-3 are activated by specific chromosomal rearrangements in a subgroup of thyroid adenomasQ33538051
Senescence is an endogenous trigger for microRNA-directed transcriptional gene silencing in human cellsQ33652889
Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumorsQ41817349
Identification of mRNAs bound and regulated by human LIN28 proteins and molecular requirements for RNA recognitionQ41889151
A unique microvascular phenotype shared by juvenile hemangiomas and human placenta.Q43602972
LIN28 Regulates Stem Cell Metabolism and Conversion to Primed PluripotencyQ46190451
Propranolol for severe hemangiomas of infancy.Q46542573
NOTCH3 regulates stem-to-mural cell differentiation in infantile hemangioma.Q46898622
Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR.Q48820061
Infantile Hemangiomas: An Updated Review on Risk Factors, Pathogenesis, and Treatment.Q55394881
Diagnosis and Management of Infantile Hemangioma: Executive SummaryQ86305322
Comparative RNA-sequencing analysis of myocardial and circulating small RNAs in human heart failure and their utility as biomarkersQ34002423
Propranolol enhanced adipogenesis instead of induction of apoptosis of hemangiomas stem cellsQ34028977
Propranolol promotes accelerated and dysregulated adipogenesis in hemangioma stem cellsQ34050131
A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblastsQ34125363
A selective microRNA-based strategy inhibits restenosis while preserving endothelial functionQ34129012
MicroRNA sequence and expression analysis in breast tumors by deep sequencingQ34185623
Hemangiomas and vascular malformations in infants and children: a classification based on endothelial characteristicsQ34277771
Bioinformatic analysis of barcoded cDNA libraries for small RNA profiling by next-generation sequencingQ34353154
A randomized, controlled trial of oral propranolol in infantile hemangioma.Q34668015
Glucose transporter 1-positive endothelial cells in infantile hemangioma exhibit features of facultative stem cells.Q34734440
Mammalian miRNA curation through next-generation sequencingQ34917408
Signaling mechanisms of the epithelial-mesenchymal transitionQ35213019
Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms.Q35583640
cAMP and EPAC Signaling Functionally Replace OCT4 During Induced Pluripotent Stem Cell ReprogrammingQ35594855
Enrichment of the embryonic stem cell reprogramming factors Oct4, Nanog, Myc, and Sox2 in benign and malignant vascular tumorsQ35790043
Endothelial progenitor cells from infantile hemangioma and umbilical cord blood display unique cellular responses to endostatin.Q35849864
LIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundanceQ36354434
Barcoded cDNA library preparation for small RNA profiling by next-generation sequencingQ36429533
Propranolol Targets Hemangioma Stem Cells via cAMP and Mitogen-Activated Protein Kinase RegulationQ36440738
Reprogramming of the microRNA transcriptome mediates resistance to rapamycinQ36647195
Lin28A Binds Active Promoters and Recruits Tet1 to Regulate Gene ExpressionQ36656700
Multipotential stem cells recapitulate human infantile hemangioma in immunodeficient miceQ36700275
MYCN-driven regulatory mechanisms controlling LIN28B in neuroblastomaQ36815139
Pathogenesis of infantile haemangioma.Q37001304
Endothelial and circulating C19MC microRNAs are biomarkers of infantile hemangiomaQ37268517
Repurposing Drugs in Oncology (ReDO)-Propranolol as an anti-cancer agentQ37404693
The LIN28/let-7 Pathway in Cancer.Q37723361
Pregnancy-associated miRNA-clusters.Q38083845
Selective activation of miRNAs of the primate-specific chromosome 19 miRNA cluster (C19MC) in cancer and stem cells and possible contribution to regulation of apoptosisQ38713237
The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summaryQ38829244
Rapamycin resistance is linked to defective regulation of Skp2.Q39400489
The primate-specific microRNA gene cluster (C19MC) is imprinted in the placentaQ39683222
Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells.Q39841597
Comprehensive microRNA profiling reveals a unique human embryonic stem cell signature dominated by a single seed sequenceQ39993069
P4510describes a project that usesImageJQ1659584
P433issue6
P921main subjectinfantile hemangiomaQ52771370
P304page(s)1321-1332
P577publication date2018-05-03
P1433published inArteriosclerosis, Thrombosis, and Vascular BiologyQ4797542
P1476titleModulation of LIN28B/Let-7 Signaling by Propranolol Contributes to Infantile Hemangioma Involution
P478volume38