The miR-3127-5p/p-STAT3 axis up-regulates PD-L1 inducing chemoresistance in non-small-cell lung cancer

scientific article published on 04 May 2018

The miR-3127-5p/p-STAT3 axis up-regulates PD-L1 inducing chemoresistance in non-small-cell lung cancer is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/JCMM.13657
P932PMC publication ID6050495
P698PubMed publication ID29726585

P50authorWen GaoQ88567525
P2093author name stringLin Zhou
Liming Lu
Yun Wu
Dandan Zhao
Ruyong Yao
Yifeng Sun
Dongfang Tang
P2860cites workPD-L1 is commonly expressed and transcriptionally regulated by STAT3 and MYC in ALK-negative anaplastic large-cell lymphoma.Q55003479
ALK-Testing in non-small cell lung cancer (NSCLC): Immunohistochemistry (IHC) and/or fluorescence in-situ Hybridisation (FISH)?: Statement of the Germany Society for Pathology (DGP) and the Working Group Thoracic Oncology (AIO) of the German Cancer SQ56964755
Avelumab, an anti-PD-L1 monoclonal antibody, shows activity in various tumour typesQ87742270
Cancer-associated oxidoreductase ERO1-α promotes immune escape through up-regulation of PD-L1 in human breast cancerQ33648621
Phosphorylation-regulated degradation of the tumor-suppressor form of PED by chaperone-mediated autophagy in lung cancer cells.Q34400928
The clinical relevance of the miR-197/CKS1B/STAT3-mediated PD-L1 network in chemoresistant non-small-cell lung cancerQ35399165
miR-424(322) reverses chemoresistance via T-cell immune response activation by blocking the PD-L1 immune checkpointQ36875531
Activation of the PD-1/PD-L1 immune checkpoint confers tumor cell chemoresistance associated with increased metastasis.Q36963025
Reduced miR-3127-5p expression promotes NSCLC proliferation/invasion and contributes to dasatinib sensitivity via the c-Abl/Ras/ERK pathwayQ37734888
Role of circulating-tumor DNA analysis in non-small cell lung cancerQ38594780
An IL-27/Stat3 axis induces expression of programmed cell death 1 ligands (PD-L1/2) on infiltrating macrophages in lymphomaQ38749945
Optimal management of EGFR-mutant non-small cell lung cancer with disease progression on first-line tyrosine kinase inhibitor therapyQ39413872
Sesamin induces autophagy in colon cancer cells by reducing tyrosine phosphorylation of EphA1 and EphB2.Q39556548
A population-based comparative effectiveness study of chemoradiation regimens and sequences in stage III non-small cell lung cancerQ40155605
Predictive factors for EGFR-tyrosine kinase inhibitor retreatment in patients with EGFR-mutated non-small-cell lung cancer - A multicenter retrospective SEQUENCE studyQ40329884
CLDN1 Increases Drug Resistance of Non-Small Cell Lung Cancer by Activating Autophagy via Up-Regulation of ULK1 Phosphorylation.Q41076029
mTORC1-independent autophagy regulates receptor tyrosine kinase phosphorylation in colorectal cancer cells via an mTORC2-mediated mechanismQ42509388
Distinct PD-L1 binding characteristics of therapeutic monoclonal antibody durvalumabQ47783661
Therapeutic implication of 'Iturin A' for targeting MD-2/TLR4 complex to overcome angiogenesis and invasion.Q50769962
The EGFR pathway is involved in the regulation of PD-L1 expression via the IL-6/JAK/STAT3 signaling pathway in EGFR-mutated non-small cell lung cancer.Q51474909
P4510describes a project that usesImageJQ1659584
P921main subjectlung cancerQ47912
P577publication date2018-05-04
P1433published inJournal of Cellular and Molecular MedicineQ1524063
P1476titleThe miR-3127-5p/p-STAT3 axis up-regulates PD-L1 inducing chemoresistance in non-small-cell lung cancer

Reverse relations

cites work (P2860)
Q104459235A multivariable miRNA signature delineates the systemic hemodynamic impact of arteriovenous shunt placement in a pilot study
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Q92807802Knockdown of LncRNA SCAMP1 suppressed malignant biological behaviours of glioma cells via modulating miR-499a-5p/LMX1A/NLRC5 pathway
Q92080181Protective effect of hsa-miR-570-3p targeting CD274 on triple negative breast cancer by blocking PI3K/AKT/mTOR signaling pathway
Q93147363Recent Findings in the Regulation of Programmed Death Ligand 1 Expression
Q99630570Resistance to PD-1/PD-L1 blockade cancer immunotherapy: mechanisms, predictive factors, and future perspectives
Q60908274The Role of Yes-Associated Protein (YAP) in Regulating Programmed Death-Ligand 1 (PD-L1) in Thoracic Cancer
Q90718904The role of cancer-derived microRNAs in cancer immune escape
Q91965847[Role of STAT3 in Resistance of Non-small Cell Lung Cancer]

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