Genomic integration of ERRγ-HNF1β regulates renal bioenergetics and prevents chronic kidney disease

scientific article published on 07 May 2018

Genomic integration of ERRγ-HNF1β regulates renal bioenergetics and prevents chronic kidney disease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1073/PNAS.1804965115
P932PMC publication ID6003475
P698PubMed publication ID29735694

P50authorChengxiang QiuQ57001920
Jian LiuQ85906796
Liming PeiQ87095573
Grant D BarishQ88595955
P2093author name stringKatalin Susztak
Benjamin J Wilkins
Juanjuan Zhao
Amanda L Allred
Caitlin McDonald
Katherine Lupino
Yasuhiro Omura
P2860cites workGenome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma.Q51915435
ERRγ Preserves Brown Fat Innate Thermogenic Activity.Q55002110
LFB1 and LFB3 homeoproteins are sequentially expressed during kidney developmentQ67882229
Autosomal recessive renal glucosuria attributable to a mutation in the sodium glucose cotransporter (SGLT2)Q28215167
Thyroid hormone receptor repression is linked to type I pneumocyte-associated respiratory distress syndromeQ28589422
A global double-fluorescent Cre reporter mouseQ29616157
A mitotic transcriptional switch in polycystic kidney diseaseQ30498985
Mitochondrial dysregulation and oxidative stress in patients with chronic kidney diseaseQ33495688
Bilateral renal agenesis/hypoplasia/dysplasia (BRAHD): postmortem analysis of 45 cases with breakpoint mapping of two de novo translocationsQ33682115
Mitochondrial dysfunction in inherited renal disease and acute kidney injuryQ33793389
SGLT2 inhibition--a novel strategy for diabetes treatmentQ34117872
SGLT2 mediates glucose reabsorption in the early proximal tubule.Q34457264
Estrogen-related receptor α (ERRα) and ERRγ are essential coordinators of cardiac metabolism and functionQ35165143
Dependence of hippocampal function on ERRγ-regulated mitochondrial metabolismQ35372129
A mitochondrial bioenergetic etiology of diseaseQ36734995
ERRγ Is Required for the Metabolic Maturation of Therapeutically Functional Glucose-Responsive β CellsQ36799671
Nuclear receptor/microRNA circuitry links muscle fiber type to energy metabolismQ36891068
HNF6 and Rev-erbα integrate hepatic lipid metabolism by overlapping and distinct transcriptional mechanismsQ37151371
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Transcriptional control of mitochondrial biogenesis and functionQ37540228
Estrogen related receptors (ERRs): a new dawn in transcriptional control of mitochondrial gene networksQ37865795
Mitochondrial dysfunction in the pathophysiology of renal diseasesQ38168664
The mechanisms and therapeutic potential of SGLT2 inhibitors in diabetes mellitus.Q38262227
HNF1B-associated renal and extra-renal disease-an expanding clinical spectrum.Q38299096
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The next generation of therapeutics for chronic kidney diseaseQ38845590
ERRγ: a Junior Orphan with a Senior Role in MetabolismQ38956640
A transcriptional network in polycystic kidney diseaseQ40775992
Functional and morphological abnormalities of mitochondria harbouring the tRNA(Leu)(UUR) mutation in mitochondrial DNA derived from patients with maternally inherited diabetes and deafness (MIDD) and progressive kidney disease.Q40956251
Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis developmentQ41088301
GDF15 is a heart-derived hormone that regulates body growthQ41198863
Esrrg functions in early branch generation of the ureteric bud and is essential for normal development of the renal papillaQ42148107
Exercise and PGC-1α-independent synchronization of type I muscle metabolism and vasculature by ERRγ.Q42723877
NR4A orphan nuclear receptors are transcriptional regulators of hepatic glucose metabolismQ46057176
Mitochondrial Abnormality Facilitates Cyst Formation in Autosomal Dominant Polycystic Kidney DiseaseQ46290342
Complementary Roles of Estrogen-Related Receptors in Brown Adipocyte Thermogenic FunctionQ46346065
Mitochondrial Etiology of Neuropsychiatric Disorders.Q47888701
Mitochondrial energetics in the kidneyQ47958098
Divergence of melanocortin pathways in the control of food intake and energy expenditureQ48707234
Progressive nephropathy associated with mitochondrial tRNA gene mutation.Q50478191
ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart.Q51579173
P433issue21
P921main subjectchronic renal insufficiencyQ736715
P304page(s)E4910-E4919
P577publication date2018-05-07
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleGenomic integration of ERRγ-HNF1β regulates renal bioenergetics and prevents chronic kidney disease
P478volume115