Myocardin-Related Transcription Factor A Promotes Recruitment of ITGA5+ Profibrotic Progenitors during Obesity-Induced Adipose Tissue Fibrosis

scientific article published on 01 May 2018

Myocardin-Related Transcription Factor A Promotes Recruitment of ITGA5+ Profibrotic Progenitors during Obesity-Induced Adipose Tissue Fibrosis is …
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scholarly articleQ13442814

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P356DOI10.1016/J.CELREP.2018.04.057
P932PMC publication ID6675460
P698PubMed publication ID29768198

P50authorNabil RabhiQ58035057
P2093author name stringStephen R Farmer
Jean Z Lin
P2860cites workThe myofibroblast: one function, multiple originsQ24683749
Contribution of small GTPase Rho and its target protein rock in a murine model of lung fibrosisQ32033022
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Fibrosis in human adipose tissue: composition, distribution, and link with lipid metabolism and fat mass lossQ34237665
Identification of an adipogenic niche for adipose tissue remodeling and restorationQ34289690
Time-course microarrays reveal early activation of the immune transcriptome and adipokine dysregulation leads to fibrosis in visceral adipose depots during diet-induced obesityQ34402691
Independent stem cell lineages regulate adipose organogenesis and adipose homeostasisQ34605960
Perivascular Gli1+ progenitors are key contributors to injury-induced organ fibrosis.Q34899171
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Do regional differences in adipocyte biology provide new pathophysiological insights?Q35161569
Inhibition of myocardin-related transcription factor/serum response factor signaling decreases lung fibrosis and promotes mesenchymal cell apoptosis.Q35236478
Myocardin-related transcription factors A and B are key regulators of TGF-β1-induced fibroblast to myofibroblast differentiationQ35417672
A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related FibrosisQ35587696
Adipose tissue extracellular matrix and vascular abnormalities in obesity and insulin resistanceQ35597861
Myocardin-related transcription factor-A complexes activate type I collagen expression in lung fibroblasts.Q35626103
Obesity-associated improvements in metabolic profile through expansion of adipose tissueQ35945161
Pdgfrβ+ Mural Preadipocytes Contribute to Adipocyte Hyperplasia Induced by High-Fat-Diet Feeding and Prolonged Cold Exposure in Adult MiceQ36568126
Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosisQ36638211
Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesityQ36673494
ITGAV and ITGA5 diversely regulate proliferation and adipogenic differentiation of human adipose derived stem cells.Q37057299
Metabolic dysregulation and adipose tissue fibrosis: role of collagen VI.Q37110569
Fibrosis and adipose tissue dysfunctionQ37227722
Activation of MRTF-A-dependent gene expression with a small molecule promotes myofibroblast differentiation and wound healingQ37240461
Myocardin-related transcription factor A (MRTFA) regulates the fate of bone marrow mesenchymal stem cells and its absence in mice leads to osteopeniaQ37279035
The role of the MRTF-A/SRF pathway in ocular fibrosisQ38233312
Regulation of MKL1 via actin cytoskeleton dynamics drives adipocyte differentiationQ38308746
A PDGFRα-Mediated Switch toward CD9high Adipocyte Progenitors Controls Obesity-Induced Adipose Tissue Fibrosis.Q38953153
CCG-1423: a small-molecule inhibitor of RhoA transcriptional signaling.Q40093918
Changes in integrin expression during adipocyte differentiationQ40375216
The CD9, CD81, and CD151 EC2 domains bind to the classical RGD-binding site of integrin αvβ3.Q40403704
Divergent functions of endotrophin on different cell populations in adipose tissueQ42806842
Fibronectin modulation of cell shape and lipogenic gene expression in 3T3-adipocytesQ42820082
Omental adipose tissue fibrosis and insulin resistance in severe obesity.Q43066618
Myocardin-related transcription factor A regulates conversion of progenitors to beige adipocytesQ43215836
The FAT Score, a Fibrosis Score of Adipose Tissue: Predicting Weight-Loss Outcome After Gastric BypassQ47220115
Accumulation and Changes in Composition of Collagens in Subcutaneous Adipose Tissue After Bariatric SurgeryQ50277523
Probability of an Obese Person Attaining Normal Body Weight: Cohort Study Using Electronic Health Records.Q53953813
The tetraspanin CD9 regulates migration, adhesion, and homing of human cord blood CD34+ hematopoietic stem and progenitor cells.Q54633960
Immune Cell Toll-like Receptor 4 Mediates the Development of Obesity- and Endotoxemia-Associated Adipose Tissue FibrosisQ57420137
P4510describes a project that usesImageJQ1659584
P433issue7
P304page(s)1977-1987
P577publication date2018-05-01
P1433published inCell ReportsQ5058165
P1476titleMyocardin-Related Transcription Factor A Promotes Recruitment of ITGA5+ Profibrotic Progenitors during Obesity-Induced Adipose Tissue Fibrosis
P478volume23

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cites work (P2860)
Q57029307Fat fibrosis: friend or foe?
Q98226258Fate of Adipose Progenitor Cells in Obesity-Related Chronic Inflammation
Q110644614SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
Q89664945The Adipocyte Acquires a Fibroblast-Like Transcriptional Signature in Response to a High Fat Diet
Q90657726Transcriptional Control of Brown and Beige Fat Development and Function

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