Physiological hyperinsulinemia caused by acute hyperglycemia minimizes renal sodium loss by direct action on kidneys

scientific article published on 23 May 2018

Physiological hyperinsulinemia caused by acute hyperglycemia minimizes renal sodium loss by direct action on kidneys is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1152/AJPREGU.00016.2018
P932PMC publication ID6172628
P698PubMed publication ID29791205

P2093author name stringMichael W Brands
Debra L Irsik
P2860cites workNa+-sensitive elevation in blood pressure is ENaC independent in diet-induced obesity and insulin resistanceQ28394234
Inhibition of thromboxane synthesis attenuates insulin hypertension in ratsQ28575683
Increasing plasma [K+] by intravenous potassium infusion reduces NCC phosphorylation and drives kaliuresis and natriuresisQ33568904
Acute insulin stimulation induces phosphorylation of the Na-Cl cotransporter in cultured distal mpkDCT cells and mouse kidneyQ34016466
Insulin secretion in response to protein ingestionQ34084247
The effect of insulin on renal handling of sodium, potassium, calcium, and phosphate in manQ34477072
Chronic sodium-retaining action of insulin in diabetic dogsQ34784142
Cross-talk between insulin and IGF-1 receptors in the cortical collecting duct principal cells: implication for ENaC-mediated Na+ reabsorption.Q35274091
Chronic intrarenal insulin replacement reverses diabetes mellitus-induced natriuresis and diuresisQ35696971
Effects of insulin on Na and K transporters in the rat CCDQ35993950
Regulation of the human Na+-dependent glucose cotransporter hSGLT2.Q36175724
Insulin and IGF-1 activate Kir4.1/5.1 channels in cortical collecting duct principal cells to control basolateral membrane voltage.Q36821655
Enhanced phosphorylation of Na(+)-Cl- co-transporter in experimental metabolic syndrome: role of insulinQ37619138
The normal increase in insulin after a meal may be required to prevent postprandial renal sodium and volume lossesQ38885336
Renal tubular SGK1 deficiency causes impaired K+ excretion via loss of regulation of NEDD4-2/WNK1 and ENaC.Q39893074
Extrarenal potassium homeostasisQ40084164
The effect of insulin on renal sodium metabolism. A review with clinical implicationsQ40318092
ON DIABETIC ACIDOSIS: A Detailed Study of Electrolyte Balances Following the Withdrawal and Reestablishment of Insulin TherapyQ40977887
Hormonal regulation of ENaCs: insulin and aldosteroneQ41037409
Insulin stimulates SGLT2-mediated tubular glucose absorption via oxidative stress generationQ41227936
Independent regulation of in vivo insulin action on glucose versus K(+) uptake by dietary fat and K(+) contentQ43935382
Glomerular hemodynamic alterations during acute hyperinsulinemia in normal and diabetic ratsQ44785201
Insulin-induced phosphorylation of ENaC correlates with increased sodium channel function in A6 cellsQ45050318
State-space models of insulin and glucose responses to diets of varying nutrient content in men and women.Q50867704
Stimulatory effect of insulin on renal proximal tubule sodium transport is preserved in type 2 diabetes with nephropathy.Q53548155
Trafficking of ENaC subunits in response to acute insulin in mouse kidneyQ62982316
Hypertension during chronic hyperinsulinemia in rats is not salt-sensitiveQ67727660
Effects of insulin on vasoconstriction induced by thromboxane A2 in porcine coronary arteryQ68506555
Plasma glucose and insulin profiles in normal subjects ingesting diets of varying carbohydrate, fat, and protein contentQ69909292
Insulin increases loop segment chloride reabsorption in the euglycemic ratQ70231659
Cardiac output and renal function during insulin hypertension in Sprague-Dawley ratsQ71405071
Insulin-induced hypertension in rats depends on an intact renin-angiotensin systemQ73205890
Decreased cardiac output at the onset of diabetes: renal mechanisms and peripheral vasoconstrictionQ73711709
Maintenance of baseline angiotensin II potentiates insulin hypertension in ratsQ74165888
Rapid dephosphorylation of the renal sodium chloride cotransporter in response to oral potassium intake in miceQ86215259
Chronic renal artery insulin infusion increases mean arterial pressure in male Sprague-Dawley ratsQ89130238
P433issue3
P921main subjecthyperglycemiaQ271993
P304page(s)R547-R552
P577publication date2018-05-23
P1433published inAmerican Journal of Physiology - Regulatory, Integrative and Comparative PhysiologyQ2201819
P1476titlePhysiological hyperinsulinemia caused by acute hyperglycemia minimizes renal sodium loss by direct action on kidneys
P478volume315

Reverse relations

cites work (P2860)
Q92730289Ion channels and transporters in diabetic kidney disease
Q64105475Postprandial Effects on ENaC-Mediated Sodium Absorption
Q90363807Postprandial effects on electrolyte homeostasis in the kidney

Search more.