Radiosynthesis and Evaluation of [11C]HD-800, a High Affinity Brain Penetrant PET Tracer for Imaging Microtubules

scientific article published on 30 April 2018

Radiosynthesis and Evaluation of [11C]HD-800, a High Affinity Brain Penetrant PET Tracer for Imaging Microtubules is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1021/ACSMEDCHEMLETT.8B00060
P932PMC publication ID5949725
P698PubMed publication ID29795758

P2093author name stringJ John Mann
Akiva Mintz
Kiran Kumar Solingapuram Sai
J S Dileep Kumar
Jaya Prabhakaran
Christopher Whitlow
Gayathri Ramanathan
Stephanie Rideout
P2860cites workNeurodegeneration and microtubule dynamics: death by a thousand cutsQ26781649
Hereditary spastic paraplegia SPG4: what is known and not known about the diseaseQ27690406
A Case for Microtubule Vulnerability in Amyotrophic Lateral Sclerosis: Altered Dynamics During DiseaseQ28079299
Autophagy induction stabilizes microtubules and promotes axon regeneration after spinal cord injuryQ30819691
An admonition when measuring the lipophilicity of radiotracers using counting techniquesQ31997490
The neuronal cytoskeleton in acute brain injuryQ33539694
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Molecules in mammalian brain that interact with the colchicine site on tubulinQ37320144
Tubulin targets in the pathobiology and therapy of glioblastoma multiforme. I. Class III beta-tubulinQ37570220
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Molecular basis of major psychiatric diseases such as schizophrenia and depressionQ38321358
The microtubular cytoskeleton of olfactory neurons derived from patients with schizophrenia or with bipolar disorder: Implications for biomarker characterization, neuronal physiology and pharmacological screening.Q38720037
Design, Synthesis, and Preclinical Evaluation of 4-Substituted-5-methyl-furo[2,3-d]pyrimidines as Microtubule Targeting Agents That Are Effective against Multidrug Resistant Cancer CellsQ38769177
The cytoskeleton as a novel therapeutic target for old neurodegenerative disordersQ38812452
Faulty splicing and cytoskeleton abnormalities in Huntington's diseaseQ38928751
Hypoxia-inducible factor-2α (HIF-2α), but not HIF-1α, is essential for hypoxic induction of class III β-tubulin expression in human glioblastoma cellsQ38954268
TPI-287, a new taxane family member, reduces the brain metastatic colonization of breast cancer cellsQ39005489
Altered microtubule dynamics in neurodegenerative disease: Therapeutic potential of microtubule-stabilizing drugsQ39052949
The Role of Microglia in the Etiology and Evolution of Chronic Traumatic Encephalopathy.Q39149587
Microtubule-Based Transport and the Distribution, Tethering, and Organization of OrganellesQ39276510
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A Phase 1 Trial of TPI 287 as a Single Agent and in Combination With Temozolomide in Patients with Refractory or Recurrent Neuroblastoma or MedulloblastomaQ46188537
Patupilone (epothilone B) for recurrent glioblastoma: clinical outcome and translational analysis of a single-institution phase I/II trialQ48476827
Radiosynthesis and in vivo evaluation of [11C]MPC-6827, the first brain penetrant microtubule PET ligand.Q49849048
P433issue5
P921main subjectradiosynthesisQ42564982
P304page(s)452-456
P577publication date2018-04-30
P1433published inACS Medicinal Chemistry LettersQ2819061
P1476titleRadiosynthesis and Evaluation of [11C]HD-800, a High Affinity Brain Penetrant PET Tracer for Imaging Microtubules
P478volume9

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Q64888589Initial biological evaluations of 18F-KS1, a novel ascorbate derivative to image oxidative stress in cancer.cites workP2860

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