Treatment of Geographic Atrophy with Intravitreal Sirolimus: The Age-Related Eye Disease Study 2 Ancillary Study

scientific article published on 01 May 2018

Treatment of Geographic Atrophy with Intravitreal Sirolimus: The Age-Related Eye Disease Study 2 Ancillary Study is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.ORET.2017.08.015
P932PMC publication ID5967618
P698PubMed publication ID29806044

P2093author name stringJohn Hoskins
Emily Y Chew
Michael J Elman
Amitha Domalpally
Ronald P Danis
Gary Gensler
Traci E Clemons
Barbara Blodi
Michael Rauser
G Baker Hubbard
Gary E Fish
Jack Wells
Alan Margherio
Alexander Brucker
P2860cites workComplement factor H polymorphism in age-related macular degenerationQ24553334
mTOR signaling in growth control and diseaseQ24634174
An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degenerationQ28190470
Complement factor H variant increases the risk of age-related macular degenerationQ28239239
Lutein + Zeaxanthin and Omega-3 Fatty Acids for Age-Related Macular DegenerationQ28290149
Complement factor H polymorphism and age-related macular degenerationQ29614931
Prevalence of age-related macular degeneration in the United StatesQ29614964
Immunological and aetiological aspects of macular degenerationQ34207836
mTOR-mediated dedifferentiation of the retinal pigment epithelium initiates photoreceptor degeneration in mice.Q34429001
Age-related macular degeneration: genetics and biology coming togetherQ34440797
Complement activation and inflammatory processes in Drusen formation and age related macular degenerationQ34521109
A retrospective review of oral low-dose sirolimus (rapamycin) for the treatment of active uveitisQ34709640
A role for local inflammation in the formation of drusen in the aging eye.Q34809064
Intravitreal sirolimus for the treatment of geographic atrophy: results of a phase I/II clinical trialQ34956193
The Rapamune era of immunosuppression 2003: the journey from the laboratory to clinical transplantationQ35125756
Current Infectious Endophthalmitis Rates After Intravitreal Injections of Anti-Vascular Endothelial Growth Factor Agents and Outcomes of TreatmentQ35675501
Sirolimus-eluting coronary stent.Q35689893
Postinjection endophthalmitis in the comparison of age-related macular degeneration treatments trials (CATT)Q35742777
The Association between Intravitreal Steroids and Post-Injection Endophthalmitis RatesQ36217662
A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variantsQ36556369
Ocular tolerability and efficacy of intravitreal and subconjunctival injections of sirolimus in patients with non-infectious uveitis: primary 6-month results of the SAVE StudyQ36722548
Treatment of geographic atrophy with subconjunctival sirolimus: results of a phase I/II clinical trialQ36801990
Retinal precursors and the development of geographic atrophy in age-related macular degeneration.Q36991543
Immunology of age-related macular degenerationQ37614752
Postinjection Endophthalmitis Rates and Characteristics Following Intravitreal Bevacizumab, Ranibizumab, and AfliberceptQ38761162
NONINFECTIOUS VITRITIS AFTER INTRAVITREAL INJECTION OF ANTI-VEGF AGENTS: Variations in Rates and Presentation by MedicationQ40781341
Bruch's membrane and choroidal macrophages in early and advanced age-related macular degenerationQ42463987
Activated microglia in human retinitis pigmentosa, late-onset retinal degeneration, and age-related macular degenerationQ44360148
Tolerability and pharmacokinetics of intravitreal sirolimusQ46068830
Causes and prevalence of visual impairment among adults in the United StatesQ46890945
Rapamune® (RAPA, rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progressionQ57362835
A randomized, dose-escalation study of subconjunctival and intravitreal injections of sirolimus in patients with diabetic macular edemaQ82671785
P433issue5
P921main subjectsirolimusQ32089
eye diseaseQ3041498
geographic atrophyQ47200750
P304page(s)441-450
P577publication date2018-05-01
P1433published inOphthalmology RetinaQ63241478
P1476titleTreatment of Geographic Atrophy with Intravitreal Sirolimus: The Age-Related Eye Disease Study 2 Ancillary Study
P478volume2

Search more.