A phase II randomized trial comparing neoadjuvant chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in advanced squamous cell carcinoma of the pharynx or larynx

scientific article published on 01 April 2018

A phase II randomized trial comparing neoadjuvant chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in advanced squamous cell carcinoma of the pharynx or larynx is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.BJ.2018.04.003
P932PMC publication ID6138767
P698PubMed publication ID29866601

P50authorChun-Ta LiaoQ113027396
P2093author name stringJoseph Tung-Chieh Chang
Tzu-Chen Yen
Cheng-Lung Hsu
Chien-Yu Lin
Hung-Ming Wang
Shiang-Fu Huang
Chia-Hsun Hsieh
Kang-Hsing Fan
Pei-Wei Huang
Shu-Kung Ng
P2860cites workRandomized phase III trial to test accelerated versus standard fractionation in combination with concurrent cisplatin for head and neck carcinomas in the Radiation Therapy Oncology Group 0129 trial: long-term report of efficacy and toxicityQ27313572
Global burden of cancers attributable to infections in 2008: a review and synthetic analysisQ29620303
Cisplatin, tegafur, and leucovorin: a moderately effective and minimally toxic outpatient neoadjuvant chemotherapy for locally advanced squamous cell carcinoma of the head and neckQ33343214
Cisplatin, fluorouracil, and docetaxel in unresectable head and neck cancerQ33377142
Randomized trial of induction chemotherapy with cisplatin and 5-fluorouracil with or without docetaxel for larynx preservationQ33383864
A phase II study of combined oral uracil and ftorafur with leucovorin for patients with squamous cell carcinoma of the head and neckQ34315576
Induction chemotherapy followed by concurrent chemoradiotherapy (sequential chemoradiotherapy) versus concurrent chemoradiotherapy alone in locally advanced head and neck cancer (PARADIGM): a randomised phase 3 trialQ34328071
Induction chemotherapy with cisplatin and fluorouracil alone or in combination with docetaxel in locally advanced squamous-cell cancer of the head and neck: long-term results of the TAX 324 randomised phase 3 trialQ35169306
Long-term results of RTOG 91-11: a comparison of three nonsurgical treatment strategies to preserve the larynx in patients with locally advanced larynx cancerQ36625201
Pharmacoethnicity of docetaxel-induced severe neutropenia: integrated analysis of published phase II and III trials.Q37957744
Incidence trends of human papillomavirus-related head and neck cancer in Taiwan, 1995-2009.Q41662661
Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patientsQ43681440
Induction chemotherapy followed by either chemoradiotherapy or bioradiotherapy for larynx preservation: the TREMPLIN randomized phase II studyQ43772035
A randomized phase III trial comparing induction chemotherapy followed by chemoradiotherapy versus chemoradiotherapy alone as treatment of unresectable head and neck cancerQ43821393
Randomized phase III trial of neoadjuvant chemotherapy in head and neck cancer: 10-year follow-up.Q45152760
Phase II trial of cisplatin, tegafur plus uracil and leucovorin as neoadjuvant chemotherapy in patients with squamous cell carcinoma of the oropharynx and hypopharynxQ45300007
Cisplatin and fluorouracil alone or with docetaxel in head and neck cancerQ46932585
Concurrent chemoradiotherapy using cisplatin, tegafur, and leucovorin for advanced squamous cell carcinoma of the hypopharynx and oropharynxQ50354993
Prognostic impact of p16, p53, epidermal growth factor receptor, and human papillomavirus in oropharyngeal cancer in a betel nut-chewing area.Q51770826
Cisplatin and 5-fluorouracil as neoadjuvant chemotherapy: predicting response in head and neck squamous cell cancerQ71883302
Clinical experience with tegafur and low dose oral leucovorin: a dose-finding studyQ72542442
Impact of oral submucous fibrosis on chemotherapy-induced mucositis for head and neck cancer in a geographic area in which betel quid chewing is prevalentQ73082463
P433issue2
P921main subjectphase II clinical trialQ42824440
P304page(s)129-136
P577publication date2018-04-01
P1433published inBiomedical journalQ26853827
P1476titleA phase II randomized trial comparing neoadjuvant chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in advanced squamous cell carcinoma of the pharynx or larynx
P478volume41