Connexin43 Carboxyl-Terminal Domain Directly Interacts with β-Catenin

scientific article published on 24 May 2018

Connexin43 Carboxyl-Terminal Domain Directly Interacts with β-Catenin is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/IJMS19061562
P932PMC publication ID6032326
P698PubMed publication ID29882937

P2093author name stringPaul L Sorgen
Li Zheng
Ishika Basu
Gaelle Spagnol
Andrew J Trease
Matthew Cervantes
Cleofes Sarmiento
Gabriella Moore
Mirtha Gutierrez
P2860cites workDynamic trafficking and delivery of connexons to the plasma membrane and accretion to gap junctions in living cellsQ24533504
The effects of connexin phosphorylation on gap junctional communicationQ24603834
PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouseQ24619841
The many faces and functions of β-cateninQ26865781
Crystal Structure of a Full-Length β-CateninQ27650057
Phosphorylation controls the interaction of the connexin43 C-terminal domain with tubulin and microtubulesQ27678895
Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanismQ28114789
Mechanistic insights from structural studies of beta-catenin and its binding partnersQ28249766
Loss of cadherin-binding proteins β-catenin and plakoglobin in the heart leads to gap junction remodeling and arrhythmogenesisQ28257671
Eps15 interacts with ubiquitinated Cx43 and mediates its internalizationQ28583911
The carboxyl terminal domain regulates the unitary conductance and voltage dependence of connexin40 gap junction channels.Q50716462
Rapid electrical stimulation causes alterations in cardiac intercellular junction proteins of cardiomyocytes.Q53063297
Lithium chloride preconditioning optimizes skeletal myoblast functions for cellular cardiomyoplasty in vitro via glycogen synthase kinase-3beta/beta-catenin signaling.Q54792305
Protein⁻Protein Interactions with Connexin 43: Regulation and Function.Q55002494
Characterization of the pH-dependent Interaction between the Gap Junction Protein Connexin43 Carboxyl Terminus and Cytoplasmic Loop DomainsQ59241282
Cell-cell interaction in the heart via Wnt/β-catenin pathway after cardiac injuryQ37707161
Specific Cx43 phosphorylation events regulate gap junction turnover in vivoQ37707287
Molecular connexin partner remodeling orchestrates connexin traffic: from physiology to pathophysiology.Q38007019
Wnt/β-catenin signalling: from plasma membrane to nucleusQ38076192
Effect of wnt-1 and related proteins on gap junctional communication in Xenopus embryosQ38533980
The connexin 43 C-terminus: A tail of many tales.Q38773843
Beta-catenin in diseaseQ38948134
Defective signaling, osteoblastogenesis and bone remodeling in a mouse model of connexin 43 C-terminal truncationQ39042167
Context dependent reversion of tumor phenotype by connexin-43 expression in MDA-MB231 cells and MCF-7 cells: role of β-catenin/connexin43 associationQ39080279
Spatio-temporal regulation of connexin43 phosphorylation and gap junction dynamicsQ39245781
Intracellular trafficking pathways of Cx43 gap junction channelsQ39347104
Cross-regulation of Connexin43 and β-catenin influences differentiation of human neural progenitor cellsQ40137679
Ubiquitin protein ligase Nedd4 binds to connexin43 by a phosphorylation-modulated processQ40239765
Gap junction protein connexin-43 interacts directly with microtubulesQ40781090
Identification of connexin43 as a functional target for Wnt signalling.Q41040243
Connexins, connexons, and intercellular communicationQ41114815
Cardiac malformation in neonatal mice lacking connexin43.Q41358695
Wnt/β-catenin pathway in arrhythmogenic cardiomyopathyQ41694294
Role of the carboxyl terminal of connexin43 in transjunctional fast voltage gatingQ42671777
pH-dependent intramolecular binding and structure involving Cx43 cytoplasmic domainsQ44085071
Lithium chloride regulates connexin43 in skeletal myoblasts in vitro: possible involvement in Wnt/beta-catenin signalingQ46274775
Intramolecular signaling in a cardiac connexin: Role of cytoplasmic domain dimerization.Q48015814
Drebrin is a novel connexin-43 binding partner that links gap junctions to the submembrane cytoskeletonQ28594219
Structural changes in the carboxyl terminus of the gap junction protein connexin43 indicates signaling between binding domains for c-Src and zonula occludens-1Q28909825
DICHROWEB, an online server for protein secondary structure analyses from circular dichroism spectroscopic dataQ29617363
Protein secondary structure analyses from circular dichroism spectroscopy: methods and reference databasesQ29617578
Structural and molecular mechanisms of gap junction remodeling in epicardial border zone myocytes following myocardial infarctionQ30157310
Structural changes in the carboxyl terminus of the gap junction protein connexin 40 caused by the interaction with c-Src and zonula occludens-1.Q30157630
pH-dependent dimerization of the carboxyl terminal domain of Cx43.Q30163957
Regulation of connexin43 function by activated tyrosine protein kinasesQ30176872
Microtubule plus-end-tracking proteins target gap junctions directly from the cell interior to adherens junctionsQ30479975
In vitro motility of liver connexin vesicles along microtubules utilizes kinesin motorsQ30501622
Phosphatase-resistant gap junctions inhibit pathological remodeling and prevent arrhythmiasQ30501712
Actin cytoskeleton rest stops regulate anterograde traffic of connexin 43 vesicles to the plasma membrane.Q30538574
TC-PTP directly interacts with connexin43 to regulate gap junction intercellular communicationQ33980542
Intramolecular interactions mediate pH regulation of connexin43 channelsQ34017364
Gap junctions: structure and function (Review).Q34139778
Molecular dissection of transjunctional voltage dependence in the connexin-32 and connexin-43 junctionsQ34171264
Multisubunit assembly of an integral plasma membrane channel protein, gap junction connexin43, occurs after exit from the ERQ34306752
Connexin 43 connexon to gap junction transition is regulated by zonula occludens-1.Q34888171
Protein kinase A activation enhances β-catenin transcriptional activity through nuclear localization to PML bodiesQ35316688
Phosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activityQ35748395
Molecular mechanisms regulating formation, trafficking and processing of annular gap junctionsQ36031604
Connexin43 Forms Supramolecular Complexes through Non-Overlapping Binding Sites for Drebrin, Tubulin, and ZO-1.Q36046660
Characterization of the structure and intermolecular interactions between the connexin 32 carboxyl-terminal domain and the protein partners synapse-associated protein 97 and calmodulinQ36201794
Phosphorylation at S365 is a gatekeeper event that changes the structure of Cx43 and prevents down-regulation by PKC.Q36274509
v-Src phosphorylation of connexin 43 on Tyr247 and Tyr265 disrupts gap junctional communicationQ36377645
Structural Studies of the Nedd4 WW Domains and Their Selectivity for the Connexin43 (Cx43) Carboxyl TerminusQ36755078
Gap junctional complexes: from partners to functions.Q36824314
Remodelling of gap junctions and connexin expression in diseased myocardium.Q36870641
The "tail" of Connexin43: An unexpected journey from alternative translation to trafficking.Q36902136
Connexin 43 in LA-25 cells with active v-src is phosphorylated on Y247, Y265, S262, S279/282, and S368 via multiple signaling pathwaysQ37003397
Effects of phosphorylation on the structure and backbone dynamics of the intrinsically disordered connexin43 C-terminal domainQ37112753
Proteins and mechanisms regulating gap-junction assembly, internalization, and degradationQ37158482
Wnt-1 regulation of connexin43 in cardiac myocytesQ37174801
Carboxy terminus and pore-forming domain properties specific to Cx37 are necessary for Cx37-mediated suppression of insulinoma cell proliferationQ37439721
The gap junction proteome and its relationship to diseaseQ37640469
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue6
P577publication date2018-05-24
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleConnexin43 Carboxyl-Terminal Domain Directly Interacts with β-Catenin
P478volume19

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cites work (P2860)
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Q61448933Emerging roles of gap junction proteins connexins in cancer metastasis, chemoresistance and clinical application
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Q89682152The Role of Connexin Channels in the Response of Mechanical Loading and Unloading of Bone