Diet Modifies Colonic Microbiota and CD4+ T-Cell Repertoire to Induce Flares of Colitis in Mice With Myeloid-Cell Expression of Interleukin 23

scientific article published on 15 June 2018

Diet Modifies Colonic Microbiota and CD4+ T-Cell Repertoire to Induce Flares of Colitis in Mice With Myeloid-Cell Expression of Interleukin 23 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1053/J.GASTRO.2018.06.034
P932PMC publication ID6174107
P698PubMed publication ID29909020

P50authorZhengxiang HeQ56389260
Lili ChenQ56796365
Anitha JayaprakashQ57320103
Jose C ClementeQ87191879
Sebastiao N Martins-FilhoQ88301922
Glaucia C FurtadoQ90495838
P2093author name stringJeremiah J Faith
Sergio A Lira
Juan J Lafaille
Jean-Frederic Colombel
Ravi Sachidanandam
Alina Cornelia Iuga
Madhura Deshpande
P2860cites workNovel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12Q24290619
A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23RQ24297906
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QIIME allows analysis of high-throughput community sequencing dataQ24616873
Interleukin-23 drives innate and T cell-mediated intestinal inflammationQ24677051
Differential diagnosis in inflammatory bowel disease colitis: state of the art and future perspectivesQ28085134
Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature deathQ28199430
A genome-wide association study identifies IL23R as an inflammatory bowel disease geneQ28270603
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Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor.Q33662701
Ulcerative colitis and irritable bowel patients exhibit distinct abnormalities of the gut microbiota.Q33745764
Role of the gut microbiota in immunity and inflammatory diseaseQ34036490
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Diet as a Trigger or Therapy for Inflammatory Bowel Diseases.Q34543673
IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis.Q34572769
Interplay of host microbiota, genetic perturbations, and inflammation promotes local development of intestinal neoplasms in miceQ35109824
The gut microbiota in mouse models of inflammatory bowel diseaseQ35117031
Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/- miceQ36087089
A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen SusceptibilityQ36198073
Acute gastrointestinal infection induces long-lived microbiota-specific T cell responsesQ37200518
Host and microbiota interactions are critical for development of murine Crohn's-like ileitis.Q37265536
IL-23R+ innate lymphoid cells induce colitis via interleukin-22-dependent mechanismQ37325464
IL-23 is critical for induction of arthritis, osteoclast formation, and maintenance of bone mass.Q37497970
An Examination of Diet for the Maintenance of Remission in Inflammatory Bowel DiseaseQ37729775
Diet and microbiota in inflammatory bowel disease: The gut in disharmonyQ37730870
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Interleukin-23 is sufficient to induce rapid de novo gut tumorigenesis, independent of carcinogens, through activation of innate lymphoid cells.Q38444161
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Profoundly Expanded T-cell Clones in the Inflamed and Uninflamed Intestine of Patients With Crohn's DiseaseQ40351437
Epithelial-derived IL-33 promotes intestinal tumorigenesis in Apc Min/+ miceQ41019883
Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology.Q41904687
IL-23 activates innate lymphoid cells to promote neonatal intestinal pathology.Q41964089
Interleukin-23 drives intestinal inflammation through direct activity on T cellsQ42083897
Ustekinumab induction and maintenance therapy in refractory Crohn's diseaseQ42514321
Circulating and Tissue-Resident CD4+ T Cells With Reactivity to Intestinal Microbiota Are Abundant in Healthy Individuals and Function Is Altered During InflammationQ44458138
Clinical course during the first 10 years of ulcerative colitis: results from a population-based inception cohort (IBSEN Study).Q44791207
IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4-CD8- entheseal resident T cellsQ46043893
Diversity of mucosa-associated microbiota in active and inactive ulcerative colitisQ46339795
Opposing consequences of IL-23 signaling mediated by innate and adaptive cells in chemically induced colitis in mice.Q46413941
Induction therapy with the selective interleukin-23 inhibitor risankizumab in patients with moderate-to-severe Crohn's disease: a randomised, double-blind, placebo-controlled phase 2 studyQ46482643
Efficacy and Safety of MEDI2070, an Antibody Against Interleukin 23, in Patients With Moderate to Severe Crohn's Disease: A Phase 2a StudyQ46587088
Interactions between diet and the intestinal microbiota alter intestinal permeability and colitis severity in mice.Q47365730
Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies.Q47758448
Research Gaps in Diet and Nutrition in Inflammatory Bowel Disease. A Topical Review by D-ECCO Working Group [Dietitians of ECCO].Q47923338
Systemic activation and antigen-driven oligoclonal expansion of T cells in a mouse model of colitis.Q52170642
Characterization of T-cell Receptor Repertoire in Inflamed Tissues of Patients with Crohn's Disease Through Deep Sequencing.Q53109633
P433issue4
P304page(s)1177-1191.e16
P577publication date2018-06-15
P1433published inGastroenterologyQ4039279
P1476titleDiet Modifies Colonic Microbiota and CD4+ T-Cell Repertoire to Induce Flares of Colitis in Mice With Myeloid-Cell Expression of Interleukin 23
P478volume155

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cites work (P2860)
Q64994358Differential Pathogenic Th17 Profile in Mesenteric Lymph Nodes of Crohn's Disease and Ulcerative Colitis Patients.
Q90495846Interleukin 22 disrupts pancreatic function in newborn mice expressing IL-23
Q91615855Macrophage interactions with fungi and bacteria in inflammatory bowel disease
Q95300919Skin expression of IL-23 drives the development of psoriasis and psoriatic arthritis in mice

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