Mycophenolic acid concentrations in peripheral blood mononuclear cells are associated with the incidence of rejection in renal transplant recipients

scientific article published on 07 August 2018

Mycophenolic acid concentrations in peripheral blood mononuclear cells are associated with the incidence of rejection in renal transplant recipients is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/BCP.13704
P932PMC publication ID6138476
P698PubMed publication ID29974488

P50authorBenedetta C SallustioQ88974744
P2093author name stringAndrew A Somogyi
Jonathan Tuke
Robert P Carroll
Brett C McWhinney
Janet K Coller
Zaipul I Md Dom
P2860cites workMycophenolic acid quantification in human peripheral blood mononuclear cells using liquid chromatography-tandem mass spectrometryQ85987982
A New Statistical Method for Haplotype Reconstruction from Population DataQ27860495
Characterization of human type I and type II IMP dehydrogenasesQ28623113
Multidrug resistance protein (MRP) activity in normal mature leukocytes and CD34-positive hematopoietic cells from peripheral bloodQ32101964
Current issues in therapeutic drug monitoring of mycophenolic acid: report of a roundtable discussionQ34321841
Mycophenolic acid pharmacokinetics and related outcomes early after renal transplantQ35826828
Therapeutic drug monitoring of mycophenolate mofetil in transplantationQ36455259
Inosine monophosphate dehydrogenase (IMPDH) activity as a pharmacodynamic biomarker of mycophenolic acid effects in pediatric kidney transplant recipients.Q37161962
Consensus report on therapeutic drug monitoring of mycophenolic acid in solid organ transplantationQ37670499
Impact of ABCC2 haplotypes on transcriptional and posttranscriptional gene regulation and function.Q39721177
Banff 07 classification of renal allograft pathology: updates and future directionsQ40121163
The pharmacokinetics and pharmacodynamics of mycophenolate mofetil in younger and elderly renal transplant recipientsQ40501892
P-glycoprotein expression and function in circulating blood cells from normal volunteers.Q41472406
Mycophenolic acid binding to human serum albumin: characterization and relation to pharmacodynamicsQ41674253
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: TransportersQ42660436
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: EnzymesQ42660454
The pharmacokinetic-pharmacodynamic relationship for total and free mycophenolic Acid in pediatric renal transplant recipients: a report of the german study group on mycophenolate mofetil therapy.Q42670520
Inosine monophosphate dehydrogenase messenger RNA expression is correlated to clinical outcomes in mycophenolate mofetil-treated kidney transplant patients, whereas inosine monophosphate dehydrogenase activity is not.Q43286711
Clinical efficacy and toxicity profile of tacrolimus and mycophenolic acid in relation to combined long-term pharmacokinetics in de novo renal allograft recipientsQ43463833
Pharmacokinetic basis for the efficient and safe use of low-dose mycophenolate mofetil in combination with tacrolimus in kidney transplantation.Q43654390
Monitoring of inosine monophosphate dehydrogenase activity and expression during the early period of mycophenolate mofetil therapy in de novo renal transplant patientsQ44065833
Cyclosporine lymphocyte versus whole blood pharmacokinetic monitoring: correlation with histological findingsQ44511304
Pre-transplant inosine monophosphate dehydrogenase activity is associated with clinical outcome after renal transplantationQ45171034
Validation of an LC-MS/MS method for the quantification of mycophenolic acid in human kidney transplant biopsies.Q45905123
Improved assay for the nonradioactive determination of inosine 5'-monophosphate dehydrogenase activity in peripheral blood mononuclear cells.Q46068408
Validation of a liquid chromatography-mass spectrometric assay for tacrolimus in peripheral blood mononuclear cellsQ46213509
Validation of a high-performance liquid chromatography method for the measurement of mycophenolic acid and its glucuronide metabolites in plasmaQ46313857
Renal glucuronidation and multidrug resistance protein 2-/ multidrug resistance protein 4-mediated efflux of mycophenolic acid: interaction with cyclosporine and tacrolimus.Q46498636
Maximum a posteriori bayesian estimation of mycophenolic acid pharmacokinetics in renal transplant recipients at different postgrafting periodsQ46500161
The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY.Q47139831
Inosine monophosphate dehydrogenase activity in paediatrics: age-related regulation and response to mycophenolic acid.Q50972464
Plasma and intracellular pharmacokinetic-pharmacodynamic analysis of mycophenolic acid in de novo kidney transplant patients.Q52981428
Effects of human T lymphocyte activation on inosine monophosphate dehydrogenase expressionQ72666691
Membrane transport of mycophenolate mofetil and its active metabolite, mycophenolic acid in MDCK and MDR1-MDCK cell monolayersQ73618682
Multidrug resistance protein 2 genetic polymorphisms influence mycophenolic acid exposure in renal allograft recipientsQ79294815
Determination of ciclosporin A and its six main metabolites in isolated T-lymphocytes and whole blood using liquid chromatography-tandem mass spectrometryQ79775530
Cyclosporine lymphocyte maximum level monitoring in de novo kidney transplant patients: a prospective studyQ79858287
Declining intracellular T-lymphocyte concentration of cyclosporine a precedes acute rejection in kidney transplant recipientsQ80532644
Correlation of tacrolimus levels in peripheral blood mononuclear cells with histological staging of rejection after liver transplantation: preliminary results of a prospective studyQ85061519
P433issue10
P304page(s)2433-2442
P577publication date2018-08-07
P1433published inBritish Journal of Clinical PharmacologyQ176044
P1476titleMycophenolic acid concentrations in peripheral blood mononuclear cells are associated with the incidence of rejection in renal transplant recipients
P478volume84

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cites work (P2860)
Q92727373Identification of anti-flaviviral drugs with mosquitocidal and anti-Zika virus activity in Aedes aegypti
Q90482752Optimizing Mycophenolic Acid Exposure in Kidney Transplant Recipients: Time for Target Concentration Intervention

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