High-density lipoprotein inhibits serum amyloid A-mediated reactive oxygen species generation and NLRP3 inflammasome activation

scientific article published on 05 July 2018

High-density lipoprotein inhibits serum amyloid A-mediated reactive oxygen species generation and NLRP3 inflammasome activation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.RA118.002428
P932PMC publication ID6109913
P698PubMed publication ID29976759

P50authorPreetha ShridasQ88817323
P2093author name stringNancy R Webb
Maria C De Beer
P2860cites workProtein measurement with the Folin phenol reagentQ20900776
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Serum amyloid A, the major vertebrate acute-phase reactantQ28145306
Serum amyloid A induces IL-8 secretion through a G protein-coupled receptor, FPRL1/LXA4RQ28209447
Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathwayQ28236043
Is serum amyloid A an endogenous TLR4 agonist?Q28267453
SAA does not induce cytokine production in physiological conditionsQ28279562
Cutting edge: TLR2 is a functional receptor for acute-phase serum amyloid AQ28284501
Serum amyloid A is a ligand for scavenger receptor class B type I and inhibits high density lipoprotein binding and selective lipid uptakeQ28294881
Nonexpression of the Human Serum Amyloid A Three (SAA3) GeneQ28305684
CD36 is a novel serum amyloid A (SAA) receptor mediating SAA binding and SAA-induced signaling in human and rodent cellsQ28580132
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expressionQ29615589
The NALP3 inflammasome is involved in the innate immune response to amyloid-betaQ29615595
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentrationQ29615596
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystalsQ29615704
Interleukin-1-receptor antagonist in type 2 diabetes mellitusQ29619001
NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production?Q29619524
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Genetic and pharmacologic disruption of interleukin-1β signaling inhibits experimental aortic aneurysm formationQ30414961
Binding, trafficking and accumulation of serum amyloid A in peritoneal macrophagesQ30985170
Serum amyloid A induces NLRP-3-mediated IL-1β secretion in neutrophilsQ33638132
Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammationQ33644572
Differential expression of C-reactive protein and serum amyloid A in different cell types in the lung tissue of chronic obstructive pulmonary disease patientsQ33732176
A pertussis toxin sensitive G-protein-independent pathway is involved in serum amyloid A-induced formyl peptide receptor 2-mediated CCL2 productionQ33809151
High-density lipoprotein loses its anti-inflammatory capacity by accumulation of pro-inflammatory-serum amyloid A.Q34157008
Impact of serum amyloid A on high density lipoprotein composition and levelsQ34187954
Differential requirement of P2X7 receptor and intracellular K+ for caspase-1 activation induced by intracellular and extracellular bacteriaQ50072056
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Serum amyloid A impairs the antiinflammatory properties of HDL.Q55077919
Interaction of the inflammasome genes CARD8 and NLRP3 in abdominal aortic aneurysmsQ57154848
The acute-phase protein serum amyloid A induces endothelial dysfunction that is inhibited by high-density lipoproteinQ58645726
Serum amyloid A induction of cytokines in monocytes/macrophages and lymphocytesQ58645765
Inhibition of cell adhesion to glycoproteins of the extracellular matrix by peptides corresponding to serum amyloid A. Toward understanding the physiological role of an enigmatic proteinQ72066987
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Acute inflammation, acute phase serum amyloid A and cholesterol metabolism in the mouseQ73370318
Chronic angiotensin II infusion promotes atherogenesis in low density lipoprotein receptor -/- miceQ73865404
The proinflammatory activity of recombinant serum amyloid A is not shared by the endogenous protein in the circulationQ83123575
Is the serum amyloid A we use really serum amyloid A? Comment on the article by Connolly et alQ87417828
Serum amyloid A1 isoforms display different efficacy at Toll-like receptor 2 and formyl peptide receptor 2.Q34615520
Characterization of the oligomerization and aggregation of human Serum Amyloid AQ34764150
Serum amyloid A activates the NLRP3 inflammasome and promotes Th17 allergic asthma in miceQ35058983
Serum amyloid A and inflammation in diabetic kidney disease and podocytesQ35138098
NLRP3 inflammasome plays a critical role in the pathogenesis of hydroxyapatite-associated arthropathyQ35202688
Regulation of inflammasome activationQ35456425
Proteolysis of serum amyloid A and AA amyloid proteins by cysteine proteases: cathepsin B generates AA amyloid proteins and cathepsin L may prevent their formation.Q35555630
Thermal transitions in serum amyloid A in solution and on the lipid: implications for structure and stability of acute-phase HDL.Q35886290
Antiinflammatory properties of HDL.Q35919164
ATP release and purinergic signaling in NLRP3 inflammasome activationQ36515084
Pathogenic serum amyloid A 1.1 shows a long oligomer-rich fibrillation lag phase contrary to the highly amyloidogenic non-pathogenic SAA2.2.Q36562118
Deficiency of Endogenous Acute-Phase Serum Amyloid A Protects apoE-/- Mice From Angiotensin II-Induced Abdominal Aortic Aneurysm FormationQ36771716
Treating inflammation by blocking interleukin-1 in a broad spectrum of diseasesQ36816872
C-reactive protein and serum amyloid a overexpression in lung tissues of chronic obstructive pulmonary disease patients: a case-control studyQ36953097
High-density lipoprotein: antioxidant and anti-inflammatory propertiesQ37074314
Pathogenetic mechanisms of amyloid A amyloidosis.Q37218553
Adoptive transfer of M2 macrophages reduces neuropathic pain via opioid peptidesQ37322206
Serum amyloid A and pairing formyl peptide receptor 2 are expressed in corneas and involved in inflammation-mediated neovascularizationQ37729400
Immune functions of serum amyloid A.Q38067156
Antiinflammatory Therapy with Canakinumab for Atherosclerotic DiseaseQ38606033
Cellular mechanism of fibril formation from serum amyloid A1 protein.Q38715103
High-density lipoprotein reduces inflammation from cholesterol crystals by inhibiting inflammasome activation.Q38762941
Inflammasome Priming in Sterile Inflammatory Disease.Q39097515
Serum amyloid A induces CCL2 production via formyl peptide receptor-like 1-mediated signaling in human monocytesQ39943851
Serum amyloid A mediates human neutrophil production of reactive oxygen species through a receptor independent of formyl peptide receptor like-1.Q40156771
Human serum amyloid A protein. Behaviour in aqueous and urea-containing solutions and antibody productionQ42017597
Mitochondria-targeted drugs enhance Nlrp3 inflammasome-dependent IL-1β secretion in association with alterations in cellular redox and energy statusQ42056008
Circular-dichroism studies on two murine serum amyloid A proteinsQ42163690
Inhibition of human caspases by peptide-based and macromolecular inhibitorsQ42538024
A cell culture system for the study of amyloid pathogenesis. Amyloid formation by peritoneal macrophages cultured with recombinant serum amyloid AQ42795983
Serum amyloid A induces reactive oxygen species (ROS) production and proliferation of fibroblastQ42816825
Acute serum amyloid A induces migration, angiogenesis, and inflammation in synovial cells in vitro and in a human rheumatoid arthritis/SCID mouse chimera model.Q43076984
Detection of caspase activation in situ by fluorochrome-labeled caspase inhibitorsQ43746526
Promoting export of macrophage cholesterol: the physiological role of a major acute-phase protein, serum amyloid A 2.1.Q44138778
Macrophage inflammasome mediates hyperhomocysteinemia-aggravated abdominal aortic aneurysm.Q46772928
Inflammasome activation by mitochondrial oxidative stress in macrophages leads to the development of angiotensin II-induced aortic aneurysmQ46816927
Serum amyloid A-containing human high density lipoprotein 3. Density, size, and apolipoprotein compositionQ47206788
Serum Amyloid A3 is a High-Density Lipoprotein-associated Acute Phase ProteinQ47287451
P433issue34
P407language of work or nameEnglishQ1860
P921main subjectreactive oxygen speciesQ424361
P304page(s)13257-13269
P577publication date2018-07-05
P1433published inJournal of Biological ChemistryQ867727
P1476titleHigh-density lipoprotein inhibits serum amyloid A-mediated reactive oxygen species generation and NLRP3 inflammasome activation
P478volume293

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cites work (P2860)
Q91826756Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation
Q92970082Apoproteins E, A-I, and SAA in Macrophage Pathobiology Related to Atherogenesis
Q91790389Effects of D-Chiro-Inositol on Glucose Metabolism in db/db Mice and the Associated Underlying Mechanisms
Q89783235High-Density Lipoprotein (HDL) Inhibits Serum Amyloid A (SAA)-Induced Vascular and Renal Dysfunctions in Apolipoprotein E-Deficient Mice
Q64250648High-Density Lipoprotein from Chronic Kidney Disease Patients Modulates Polymorphonuclear Leukocytes
Q91972897Pharmacological Inhibition of HDAC6 Attenuates NLRP3 Inflammatory Response and Protects Dopaminergic Neurons in Experimental Models of Parkinson's Disease
Q90701560Serum Amyloid A-Mediated Inflammasome Activation of Microglial Cells in Cerebral Ischemia

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