Incidence of biomarkers in high-grade gliomas and their impact on survival in a diverse SouthEast Asian cohort - a population-based study

scientific article published on 31 January 2020

Incidence of biomarkers in high-grade gliomas and their impact on survival in a diverse SouthEast Asian cohort - a population-based study is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1186/S12885-020-6536-X
P932PMC publication ID6993394
P698PubMed publication ID32005184

P50authorNicolas Kon Kam KingQ89471302
P2093author name stringLester Lee
Beng Ti Ang
Angela An Qi See
Samantha Ya Lyn Ang
Ting Yao Ang
P2860cites workMutations in a putative global transcriptional regulator cause X-linked mental retardation with alpha-thalassemia (ATR-X syndrome)Q24311995
An integrated genomic analysis of human glioblastoma multiformeQ24648860
IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomasQ24656269
The 2007 WHO classification of tumours of the central nervous systemQ24685772
MGMT gene silencing and benefit from temozolomide in glioblastomaQ27824832
MGMT promoter methylation is prognostic but not predictive for outcome to adjuvant PCV chemotherapy in anaplastic oligodendroglial tumors: a report from EORTC Brain Tumor Group Study 26951.Q27851529
ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosisQ27852494
International retrospective study of over 1000 adults with anaplastic oligodendroglial tumorsQ30426724
Phase III trial of chemoradiotherapy for anaplastic oligodendroglioma: long-term results of RTOG 9402.Q30542081
Adjuvant procarbazine, lomustine, and vincristine chemotherapy in newly diagnosed anaplastic oligodendroglioma: long-term follow-up of EORTC brain tumor group study 26951.Q34446549
Somatic mutations in glioblastoma are associated with methylguanine-DNA methyltransferase methylation.Q35741879
Molecular genetic analysis of oligodendroglial tumors shows preferential allelic deletions on 19q and 1pQ35834029
IDH mutation and MGMT promoter methylation in glioblastoma: results of a prospective registryQ36562205
Detection of ATRX and IDH1-R132H immunohistochemistry in the progression of 211 paired gliomasQ37086042
Immunohistochemical Analysis of ATRX, IDH1 and p53 in Glioblastoma and Their Correlations with Patient Survival.Q37110440
Personalized treatment strategies in glioblastoma: MGMT promoter methylation statusQ37221207
The definition of primary and secondary glioblastomaQ38064831
A practical review of prognostic correlations of molecular biomarkers in glioblastomaQ38366346
The Effect of Molecular Diagnostics on the Treatment of GliomaQ38743781
The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summaryQ38829244
Adult infiltrating gliomas with WHO 2016 integrated diagnosis: additional prognostic roles of ATRX and TERT.Q38931930
IDH1/2 Mutation and MGMT Promoter Methylation - the Relevant Survival Predictors in Czech Patients with Brain GliomasQ39098158
The combined EGFR protein expression analysis refines the prognostic value of the MGMT promoter methylation status in glioblastomaQ39567171
Environmental risk factors for primary malignant brain tumors: a reviewQ40720873
Prognostic significance of histomolecular subgroups of adult anaplastic (WHO Grade III) gliomas: applying the 'integrated' diagnosis approachQ40993120
Immunohistochemical profiles of IDH1, MGMT and P53: practical significance for prognostication of patients with diffuse gliomasQ41756350
IDH1/IDH2 mutations define the prognosis and molecular profiles of patients with gliomas: a meta-analysisQ42096951
Is the prognostic significance of O6-methylguanine- DNA methyltransferase promoter methylation equally important in glioblastomas of patients from different continents? A systematic review with meta-analysisQ42364418
The Role of ATRX in Glioma BiologyQ42369808
ATRX immunostaining predicts IDH and H3F3A status in gliomasQ42701263
NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomideQ43245397
Significance of complete 1p/19q co-deletion, IDH1 mutation and MGMT promoter methylation in gliomas: use with caution.Q43411833
Status of O⁶ -methylguanine-DNA methyltransferase [MGMT] gene promoter methylation among patients with glioblastomas from IndiaQ44389429
Glioblastoma survival in the United States improved after Food and Drug Administration approval of bevacizumab: a population-based analysisQ44661518
O(6) -methylguanine-DNA methyltransferase (MGMT) promoter methylation and low MGMT-encoded protein expression as prognostic markers in glioblastoma patients treated with biodegradable carmustine wafer implants after initial surgery followed by radioQ44838622
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastomaQ46796397
Ethnicity delineates different genetic pathways in malignant gliomaQ46839039
Promoter Hypermethylation of the DNA Repair Gene O6‐Methylguanine‐DNA Methyltransferase is an Independent Predictor of Shortened Progression Free Survival in Patients with Low‐grade Diffuse AstrocytomasQ48311590
Glioblastoma multiforme in an Asian population: evidence for a distinct genetic pathwayQ48365352
IDH mutation and MGMT promoter methylation are associated with the pseudoprogression and improved prognosis of glioblastoma multiforme patients who have undergone concurrent and adjuvant temozolomide-based chemoradiotherapyQ48469496
MGMT promoter hypermethylation and its associations with genetic alterations in a series of 350 brain tumorsQ48686096
Co-deletion of 1p/19q as Prognostic and Predictive Biomarker for Patients in West Bohemia with Anaplastic OligodendrogliomaQ49064634
Mutant IDH1 cooperates with ATRX loss to drive the alternative lengthening of telomere (ALT) phenotype in glioma.Q52353898
Current Challenges and Opportunities in Treating Glioblastoma.Q52579808
Malignant glioma: the involvement of loss of allelic heterozygosity and PTEN mutations in a group of Malay patients.Q54646758
Mutant ATRX: uncovering a new therapeutic target for glioma.Q55456861
Clinical correlation of MGMT protein expression and promoter methylation in Chinese glioblastoma patients.Q55463316
Molecular Markers of Therapy-Resistant Glioblastoma and Potential Strategy to Combat Resistance.Q55663256
A note on quantifying follow-up in studies of failure timeQ71721709
CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2011-2015Q93177223
P433issue1
P921main subjectbiomarkerQ864574
P304page(s)79
P577publication date2020-01-31
P1433published inBMC CancerQ326300
P1476titleIncidence of biomarkers in high-grade gliomas and their impact on survival in a diverse SouthEast Asian cohort - a population-based study
P478volume20

Reverse relations

Q98291666Prognostic Nomograms for Primary High-Grade Glioma Patients in Adult: A Retrospective Study Based on the SEER Databasecites workP2860

Search more.