| scholarly article | Q13442814 |
| P2093 | author name string | William E Balch | |
| Raymond A Frizzell | |||
| Daniela Martino Roth | |||
| Mads Breum Larsen | |||
| Darren M Hutt | |||
| Sanjay Kumar Mishra | |||
| Frédéric Angles | |||
| P2860 | cites work | Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions | Q22010047 |
| Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3 | Q24312870 | ||
| Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis | Q24316177 | ||
| BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins | Q24337812 | ||
| BAG-2 acts as an inhibitor of the chaperone-associated ubiquitin ligase CHIP. | Q24534836 | ||
| A gene pair from the human major histocompatibility complex encodes large proline-rich proteins with multiple repeated motifs and a single ubiquitin-like domain | Q24558733 | ||
| Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis | Q24615395 | ||
| One step at a time: endoplasmic reticulum-associated degradation | Q24658302 | ||
| Manipulating proteostasis to repair the F508del-CFTR defect in cystic fibrosis | Q26765794 | ||
| Modulation of the maladaptive stress response to manage diseases of protein folding | Q27313626 | ||
| Structure of a Bag/Hsc70 complex: convergent functional evolution of Hsp70 nucleotide exchange factors | Q27630011 | ||
| Structural analysis of BAG1 cochaperone and its interactions with Hsc70 heat shock protein | Q27630862 | ||
| The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange | Q27660188 | ||
| BAG3: a new player in the heart failure paradigm | Q28088321 | ||
| Chaperone-assisted selective autophagy is essential for muscle maintenance | Q28115687 | ||
| Adapting proteostasis for disease intervention | Q28131818 | ||
| Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling | Q28202126 | ||
| HspB8 and Bag3: a new chaperone complex targeting misfolded proteins to macroautophagy | Q28261719 | ||
| Aggresomes: a cellular response to misfolded proteins | Q28292275 | ||
| Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity | Q28306175 | ||
| The carboxyl-terminal lobe of Hsc70 ATPase domain is sufficient for binding to BAG1. | Q33292471 | ||
| The role of the UPS in cystic fibrosis | Q33307871 | ||
| BAG2 structure, function and involvement in disease | Q33634944 | ||
| In vivo aspects of protein folding and quality control | Q38882864 | ||
| New aspects of myofibrillar myopathies. | Q38889657 | ||
| Nano-based rescue of dysfunctional autophagy in chronic obstructive lung diseases | Q38937131 | ||
| Autophagy: machinery and regulation | Q39208155 | ||
| Shaping proteostasis at the cellular, tissue, and organismal level | Q39235911 | ||
| The Role of the Multifunctional BAG3 Protein in Cellular Protein Quality Control and in Disease | Q39416466 | ||
| Crosstalk and Interplay between the Ubiquitin-Proteasome System and Autophagy | Q39457805 | ||
| Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition | Q39667316 | ||
| The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS). | Q39689378 | ||
| ∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis | Q40006173 | ||
| Dendrimer-based selective autophagy-induction rescues ΔF508-CFTR and inhibits Pseudomonas aeruginosa infection in cystic fibrosis. | Q40048899 | ||
| HspB8 chaperone activity toward poly(Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy. | Q40050938 | ||
| Cell-based assay for high-throughput quantitative screening of CFTR chloride transport agonists | Q40774846 | ||
| Bcl-2 associated athanogene 5 (Bag5) is overexpressed in prostate cancer and inhibits ER-stress induced apoptosis. | Q41071424 | ||
| Chaperone BAG6 is dispensable for MHC class I antigen processing and presentation | Q41103396 | ||
| Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell. | Q41565850 | ||
| BAG3 facilitates the clearance of endogenous tau in primary neurons | Q41813298 | ||
| WW domain of BAG3 is required for the induction of autophagy in glioma cells. | Q41815675 | ||
| GRP78 Interacting Partner Bag5 Responds to ER Stress and Protects Cardiomyocytes From ER Stress-Induced Apoptosis | Q42259754 | ||
| A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR. | Q42335301 | ||
| Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive | Q42816994 | ||
| Characterization and dynamics of aggresome formation by a cytosolic GFP-chimera | Q42870983 | ||
| Ubiquitylation of BAG-1 suggests a novel regulatory mechanism during the sorting of chaperone substrates to the proteasome | Q44151437 | ||
| A role of BAG3 in regulating SNCA/α-synuclein clearance via selective macroautophagy | Q47754806 | ||
| Role of BAG3 in cancer progression: A therapeutic opportunity. | Q47868438 | ||
| BAG3-mediated proteostasis at a glance | Q47952887 | ||
| Bag1 Co-chaperone Promotes TRC8 E3 Ligase-dependent Degradation of Misfolded Human Ether a Go-Go-related Gene (hERG) Potassium Channels. | Q48132331 | ||
| High-Content Surface and Total Expression siRNA Kinase Library Screen with VX-809 Treatment Reveals Kinase Targets that Enhance F508del-CFTR Rescue | Q48508833 | ||
| Transformative therapies for rare CFTR missense alleles | Q50069400 | ||
| Towards a rational combination therapy of cystic fibrosis: How cystamine restores the stability of mutant CFTR. | Q50878459 | ||
| Linking chanelopathies with endoplasmic reticulum associated degradation. | Q50882244 | ||
| Cystic fibrosis: A disorder with defective autophagy | Q57663495 | ||
| BAG3 and friends: co-chaperones in selective autophagy during aging and disease | Q84381212 | ||
| Cystic fibrosis | Q89219005 | ||
| Apoptosis: Silencing the death receptors | Q33641965 | ||
| The heat shock response: systems biology of proteotoxic stress in aging and disease | Q34257283 | ||
| A chaperone trap contributes to the onset of cystic fibrosis | Q34305005 | ||
| The biology of proteostasis in aging and disease | Q34467650 | ||
| Derlin-1 promotes the efficient degradation of the cystic fibrosis transmembrane conductance regulator (CFTR) and CFTR folding mutants | Q34563643 | ||
| Emergent properties of proteostasis in managing cystic fibrosis | Q34576386 | ||
| BAG3 expression in glioblastoma cells promotes accumulation of ubiquitinated clients in an Hsp70-dependent manner | Q34685246 | ||
| Simple image-based no-wash method for quantitative detection of surface expressed CFTR. | Q35770985 | ||
| Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation | Q35852856 | ||
| Ammonia Induces Autophagy through Dopamine Receptor D3 and MTOR | Q35989571 | ||
| BAG2 promotes tumorigenesis through enhancing mutant p53 protein levels and function | Q36032139 | ||
| Pharmacological rescue of the mutant cystic fibrosis transmembrane conductance regulator (CFTR) detected by use of a novel fluorescence platform | Q36071699 | ||
| Chaperone-Mediated Autophagy Protein BAG3 Negatively Regulates Ebola and Marburg VP40-Mediated Egress | Q36246422 | ||
| Hallmarks of therapeutic management of the cystic fibrosis functional landscape. | Q36279553 | ||
| gp78 functions downstream of Hrd1 to promote degradation of misfolded proteins of the endoplasmic reticulum | Q36337039 | ||
| Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ΔF508 cystic fibrosis transmembrane conductance regulator | Q36388443 | ||
| Adeno-associated virus-targeted disruption of the CFTR gene in cloned ferrets. | Q36489533 | ||
| Therapy through chaperones: sense or antisense? Cystic fibrosis as a model disease | Q36501370 | ||
| The experimental survey of protein-folding energy landscapes | Q36509336 | ||
| Small heat shock proteins target mutant cystic fibrosis transmembrane conductance regulator for degradation via a small ubiquitin-like modifier-dependent pathway | Q36523614 | ||
| Targeting the Intracellular Environment in Cystic Fibrosis: Restoring Autophagy as a Novel Strategy to Circumvent the CFTR Defect | Q36547077 | ||
| From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations | Q36574664 | ||
| CFTR function and prospects for therapy | Q37096095 | ||
| A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR | Q37100647 | ||
| Defining the disease liability of variants in the cystic fibrosis transmembrane conductance regulator gene | Q37418902 | ||
| Cysteamine re-establishes the clearance of Pseudomonas aeruginosa by macrophages bearing the cystic fibrosis-relevant F508del-CFTR mutation | Q37744944 | ||
| Molecular Chaperones as Rational Drug Targets for Parkinsons Disease Therapeutics | Q37799850 | ||
| Emerging roles of molecular chaperones and co-chaperones in selective autophagy: focus on BAG proteins. | Q37912044 | ||
| Interpretation of genetic variants | Q38171755 | ||
| Cystic fibrosis genetics: from molecular understanding to clinical application | Q38268916 | ||
| The Role of the Protein Quality Control System in SBMA. | Q38634366 | ||
| Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis | Q38708247 | ||
| Autophagy-associated proteins BAG3 and p62 in testicular cancer. | Q38808865 | ||
| Breaking BAG: The Co-Chaperone BAG3 in Health and Disease | Q38830647 | ||
| P433 | issue | 35 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | autophagy | Q288322 |
| P304 | page(s) | 13682-13695 | |
| P577 | publication date | 2018-07-09 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Silencing of the Hsp70-specific nucleotide-exchange factor BAG3 corrects the F508del-CFTR variant by restoring autophagy | |
| P478 | volume | 293 |
| Q61803810 | Adapting Proteostasis and Autophagy for Controlling the Pathogenesis of Cystic Fibrosis Lung Disease |
| Q90058197 | Individualized management of genetic diversity in Niemann-Pick C1 through modulation of the Hsp70 chaperone system |
| Q57282398 | Oxidative stress, autophagy and airway ion transport |
| Q98159107 | Self-eating: friend or foe? The emerging role of autophagy in fibrotic diseases |
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