| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Marta Obara-Michlewska | Q82865027 |
| Monika Szeliga | Q89510876 | ||
| P2860 | cites work | IDH1 and IDH2 mutations in gliomas | Q24648948 |
| Response of regional brain glutamate transaminases of rat to aluminum in protein malnutrition | Q24803267 | ||
| SLC7A11 expression is associated with seizures and predicts poor survival in patients with malignant glioma | Q27325399 | ||
| Efficient Mitochondrial Glutamine Targeting Prevails Over Glioblastoma Metabolic Plasticity. | Q48190039 | ||
| Changes in lactate dehydrogenase isoenzyme pattern in patients with tumors of the central nervous system | Q48337828 | ||
| Evidence supporting the existence of an activity-dependent astrocyte-neuron lactate shuttle | Q48371514 | ||
| Expression of Gls and Gls2 glutaminase isoforms in astrocytes. | Q48492368 | ||
| A study of glutamine synthetase in normal human brain and intracranial tumours. | Q48964630 | ||
| Combination chemotherapy in vitro exploiting glutamine metabolism of human glioma and medulloblastoma. | Q49279467 | ||
| Metabolic heterogeneity and plasticity of glioma stem cells in a mouse glioblastoma model. | Q50089305 | ||
| The Effects of Severe Hypoxia on Glycolytic Flux and Enzyme Activity in a Model of Solid Tumors. | Q51557216 | ||
| Oncogenic IDH1 Mutations Promote Enhanced Proline Synthesis through PYCR1 to Support the Maintenance of Mitochondrial Redox Homeostasis. | Q51737118 | ||
| Pseudolaric acid B triggers ferroptosis in glioma cells via activation of Nox4 and inhibition of xCT. | Q52558744 | ||
| Proline oxidase controls proline, glutamate, and glutamine cellular concentrations in a U87 glioblastoma cell line. | Q52563712 | ||
| Silencing LDHA inhibits proliferation, induces apoptosis and increases chemosensitivity to temozolomide in glioma cells. | Q52649731 | ||
| Downregulation of GLS2 in glioblastoma cells is related to DNA hypermethylation but not to the p53 status. | Q55459904 | ||
| Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo. | Q55474168 | ||
| Glucose and glutamine metabolism in C6 glioma cells studied by carbon 13 NMR. | Q55480025 | ||
| Influence of glutamine on the growth of human glioma and medulloblastoma in culture. | Q55488075 | ||
| Mitochondrial enzyme GLUD2 plays a critical role in glioblastoma progression | Q57479924 | ||
| Updates in prognostic markers for gliomas | Q58568678 | ||
| Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours | Q60683111 | ||
| Mitochondrial Substrate-Level Phosphorylation as Energy Source for Glioblastoma: Review and Hypothesis | Q60930189 | ||
| Cyclin G2 Inhibits the Warburg Effect and Tumour Progression by Suppressing LDHA Phosphorylation in Glioma | Q61809294 | ||
| Transfection with GLS2 Glutaminase (GAB) Sensitizes Human Glioblastoma Cell Lines to Oxidative Stress by a Common Mechanism Involving Suppression of the PI3K/AKT Pathway | Q61812918 | ||
| Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer | Q64055841 | ||
| R406 elicits anti-Warburg effect via Syk-dependent and -independent mechanisms to trigger apoptosis in glioma stem cells | Q64073150 | ||
| Longitudinal Measurements of Intra- and Extracellular pH Gradient in a Rat Model of Glioma. | Q64960280 | ||
| Metabonomic signature analysis in plasma samples of glioma patients based on (1)H-nuclear magnetic resonance spectroscopy | Q87421200 | ||
| Friend or foe-IDH1 mutations in glioma 10 years on | Q90025515 | ||
| Glutaminase isoenzymes in the metabolic therapy of cancer | Q90573687 | ||
| CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2012-2016 | Q91054612 | ||
| Lactate in the Regulation of Tumor Microenvironment and Therapeutic Approaches | Q91319096 | ||
| Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma | Q91471169 | ||
| Unraveling the Potential Role of Glutathione in Multiple Forms of Cell Death in Cancer Therapy | Q91690576 | ||
| Lactate from astrocytes fuels learning-induced mRNA translation in excitatory and inhibitory neurons | Q91727320 | ||
| Imidazole Ketone Erastin Induces Ferroptosis and Slows Tumor Growth in a Mouse Lymphoma Model | Q91866520 | ||
| Exchange-mode glutamine transport across CNS cell membranes | Q92253644 | ||
| Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells | Q92482501 | ||
| ASCT2: a potential cancer drug target | Q92496229 | ||
| Glioblastoma stem cells: lessons from the tumor hierarchy in a lethal cancer | Q92500797 | ||
| The Tumor Metabolic Microenvironment: Lessons from Lactate | Q92570659 | ||
| Novel analogs of sulfasalazine as system xc - antiporter inhibitors: Insights from the molecular modeling studies | Q92744584 | ||
| Epithelial membrane protein 1 promotes glioblastoma progression through the PI3K/AKT/mTOR signaling pathway | Q92981891 | ||
| Altered function of the glutamate-aspartate transporter GLAST, a potential therapeutic target in glioblastoma | Q93003308 | ||
| Glioma cells release excitotoxic concentrations of glutamate. | Q40929224 | ||
| Temozolomide arrests glioma growth and normalizes intratumoral extracellular pH. | Q41367767 | ||
| Detection and quantification of vascular endothelial growth factor/vascular permeability factor in brain tumor tissue and cyst fluid: the key to angiogenesis? | Q41446853 | ||
| Immunotherapy against the radial glia marker GLAST effectively triggers specific antitumor effectors without autoimmunity | Q41475241 | ||
| Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo | Q42198162 | ||
| Acidic extracellular microenvironment and cancer | Q42850228 | ||
| Metabolomic patterns in glioblastoma and changes during radiotherapy: a clinical microdialysis study | Q43123788 | ||
| Untreated glioblastoma multiforme: increased myo-inositol and glutamine levels in the contralateral cerebral hemisphere at proton MR spectroscopy. | Q43269542 | ||
| Characterization of oligodendrogliomas using short echo time 1H MR spectroscopic imaging | Q44309177 | ||
| Baseline levels of glucose metabolites, glutamate and glycerol in malignant glioma assessed by stereotactic microdialysis | Q44352421 | ||
| Lack of expression of the liver-type glutaminase (LGA) mRNA in human malignant gliomas. | Q45233336 | ||
| The excitatory amino acid transporter-2 induces apoptosis and decreases glioma growth in vitro and in vivo | Q45309139 | ||
| Epilepsy in glioblastoma multiforme: correlation with glutamine synthetase levels. | Q46138442 | ||
| mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT. | Q46197917 | ||
| Cystine uptake through the cystine/glutamate antiporter xCT triggers glioblastoma cell death under glucose deprivation | Q46283642 | ||
| Proline Metabolism in Cell Regulation and Cancer Biology: Recent Advances and Hypotheses | Q46291291 | ||
| Hypoxia-Inducible Factors and Cancer | Q47681462 | ||
| Expression of vascular endothelial growth factor and its receptors in the anaplastic progression of astrocytoma, oligodendroglioma, and ependymoma. | Q47822182 | ||
| The Pro-tumorigenic Effects of Metabolic Alterations in Glioblastoma Including Brain Tumor Initiating Cells | Q47834398 | ||
| Mapping Extracellular pH of Gliomas in Presence of Superparamagnetic Nanoparticles: Towards Imaging the Distribution of Drug-Containing Nanoparticles and Their Curative Effect on the Tumor Microenvironment | Q47843849 | ||
| Control of brain energy supply by astrocytes | Q48009487 | ||
| Identification of human brain tumour initiating cells | Q27860921 | ||
| The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer. | Q27863346 | ||
| Identification of a cancer stem cell in human brain tumors | Q28131688 | ||
| Compromised glutamate transport in human glioma cells: reduction-mislocalization of sodium-dependent glutamate transporters and enhanced activity of cystine-glutamate exchange | Q28140048 | ||
| Glutaminase 2 negatively regulates the PI3K/AKT signaling and shows tumor suppression activity in human hepatocellular carcinoma | Q28239503 | ||
| Determination of phosphate-activated glutaminase activity and its kinetics in mouse tissues using metabolic mapping (quantitative enzyme histochemistry) | Q28246788 | ||
| Transfection of a human glioblastoma cell line with liver-type glutaminase (LGA) down-regulates the expression of DNA-repair gene MGMT and sensitizes the cells to alkylating agents | Q28273012 | ||
| Metabolism and action of amino acid analog anti-cancer agents | Q28298599 | ||
| Silencing of GLS and overexpression of GLS2 genes cooperate in decreasing the proliferation and viability of glioblastoma cells | Q28299851 | ||
| NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells | Q29247923 | ||
| Bidirectional transport of amino acids regulates mTOR and autophagy | Q29614476 | ||
| Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction | Q29616653 | ||
| Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis | Q29617613 | ||
| Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake. | Q30572367 | ||
| Intercellular metabolic compartmentation in the brain: past, present and future | Q30931844 | ||
| Mammalian glutaminase Gls2 gene encodes two functional alternative transcripts by a surrogate promoter usage mechanism | Q31063834 | ||
| Early termination of ISRCTN45828668, a phase 1/2 prospective, randomized study of sulfasalazine for the treatment of progressing malignant gliomas in adults | Q33511367 | ||
| Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer | Q33604129 | ||
| Glutamine and glutamate as vital metabolites | Q34174552 | ||
| Hominoid-specific enzyme GLUD2 promotes growth of IDH1R132H glioma | Q34314291 | ||
| Increased expression of a glutamine transporter SNAT3 is a marker of malignant gliomas | Q34314639 | ||
| Glutamine synthetase expression as a valuable marker of epilepsy and longer survival in newly diagnosed glioblastoma multiforme | Q34587527 | ||
| Selective decrease of SN1(SNAT3) mRNA expression in human and rat glioma cells adapted to grow in acidic medium. | Q34651838 | ||
| Acidic stress promotes a glioma stem cell phenotype. | Q34985109 | ||
| Pyruvate carboxylase is required for glutamine-independent growth of tumor cells | Q35008346 | ||
| Epigenetic silencing of glutaminase 2 in human liver and colon cancers | Q35065476 | ||
| Both GLS silencing and GLS2 overexpression synergize with oxidative stress against proliferation of glioma cells. | Q35083218 | ||
| Metabolic state of glioma stem cells and nontumorigenic cells | Q35229102 | ||
| Glutamate release by primary brain tumors induces epileptic activity | Q35331983 | ||
| Compensatory glutamine metabolism promotes glioblastoma resistance to mTOR inhibitor treatment | Q35408838 | ||
| Pilot Preclinical and Clinical Evaluation of (4S)-4-(3-[18F]Fluoropropyl)-L-Glutamate (18F-FSPG) for PET/CT Imaging of Intracranial Malignancies | Q35927273 | ||
| 1H NMR metabolomics analysis of glioblastoma subtypes: correlation between metabolomics and gene expression characteristics | Q36016852 | ||
| Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC. | Q36061545 | ||
| Autocrine glutamate signaling promotes glioma cell invasion. | Q36098125 | ||
| A review of VEGF/VEGFR-targeted therapeutics for recurrent glioblastoma | Q36103026 | ||
| Therapeutic Strategy for Targeting Aggressive Malignant Gliomas by Disrupting Their Energy Balance. | Q36103152 | ||
| Lactate dehydrogenase-A inhibition induces human glioblastoma multiforme stem cell differentiation and death | Q36192530 | ||
| Metabolomics of human cerebrospinal fluid identifies signatures of malignant glioma | Q36208989 | ||
| In search of druggable targets for GBM amino acid metabolism | Q36293108 | ||
| Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma. | Q36330223 | ||
| Glutaminase: a multifaceted protein not only involved in generating glutamate. | Q36413431 | ||
| Proteomic identification of glutamine synthetase as a differential marker for oligodendrogliomas and astrocytomas. | Q36602694 | ||
| Alterations in cellular metabolome after pharmacological inhibition of Notch in glioblastoma cells | Q36633528 | ||
| Lactate promotes glutamine uptake and metabolism in oxidative cancer cells | Q36781200 | ||
| Glutamate dehydrogenase contributes to leucine sensing in the regulation of autophagy. | Q36901790 | ||
| A role for glutamate in growth and invasion of primary brain tumors | Q36917114 | ||
| Inhibition of cystine uptake disrupts the growth of primary brain tumors | Q37189377 | ||
| Metabolomics profiling in plasma samples from glioma patients correlates with tumor phenotypes | Q37190344 | ||
| Myc-Driven Glycolysis Is a Therapeutic Target in Glioblastoma | Q37230411 | ||
| mTOR complex 2 controls glycolytic metabolism in glioblastoma through FoxO acetylation and upregulation of c-Myc | Q37341834 | ||
| Metabolic response of glioblastoma cells associated with glucose withdrawal and pyruvate substitution as revealed by GC-MS. | Q37349776 | ||
| The physical chemistry of brain and neural cell membranes: an overview | Q37679740 | ||
| HIF-1 and HIF-2 transcription factors--similar but not identical | Q37732020 | ||
| Roles of glutamine in neurotransmission. | Q37948212 | ||
| Acidic extracellular pH induces vascular endothelial growth factor (VEGF) in human glioblastoma cells via ERK1/2 MAPK signaling pathway: mechanism of low pH-induced VEGF. | Q38293986 | ||
| A tale of two glutaminases: homologous enzymes with distinct roles in tumorigenesis | Q38767151 | ||
| Sulforaphane reverses chemo-resistance to temozolomide in glioblastoma cells by NF-κB-dependent pathway downregulating MGMT expression | Q38813379 | ||
| Drug repurposing: sulfasalazine sensitizes gliomas to gamma knife radiosurgery by blocking cystine uptake through system Xc-, leading to glutathione depletion | Q38896398 | ||
| Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine-γ-lyase function | Q38920349 | ||
| Mitochondrial p32 is upregulated in Myc expressing brain cancers and mediates glutamine addiction | Q38926653 | ||
| Glutamine synthetase functions as a negative growth regulator in glioma | Q39137774 | ||
| Glutamine Synthetase: Glial Localization in Brain | Q39138188 | ||
| Molecular markers in glioma | Q39148751 | ||
| Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1. | Q39636555 | ||
| Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling | Q39787798 | ||
| Characterization of the serum metabolome following radiation treatment in patients with high-grade gliomas | Q39817583 | ||
| Transfection with liver-type glutaminase cDNA alters gene expression and reduces survival, migration and proliferation of T98G glioma cells. | Q39907955 | ||
| Small interfering RNA-mediated xCT silencing in gliomas inhibits neurodegeneration and alleviates brain edema. | Q39983715 | ||
| Fatty acid oxidation is required for the respiration and proliferation of malignant glioma cells | Q40067927 | ||
| Neurological complications of antineoplastic therapy | Q40188626 | ||
| Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells | Q40522353 | ||
| Glutamine transport in C6 glioma cells shows ASCT2 system characteristics. | Q40648573 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 2 | |
| P577 | publication date | 2020-01-29 | |
| P1433 | published in | Cancers | Q27722963 |
| P1476 | title | Targeting Glutamine Addiction in Gliomas | |
| P478 | volume | 12 |
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