Dlx1/2 mice have abnormal enteric nervous system function

scientific article published on 27 February 2020

Dlx1/2 mice have abnormal enteric nervous system function is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI.INSIGHT.131494
P932PMC publication ID7101142
P698PubMed publication ID32017713

P50authorSabine SchneiderQ37929210
Robert HeuckerothQ55098159
P2093author name stringChristina M Wright
James P Garifallou
Beth A Maguire
Deepika R Kothakapa
Heather L Mentch
P2860cites workNull mutation of Dlx-2 results in abnormal morphogenesis of proximal first and second branchial arch derivatives and abnormal differentiation in the forebrainQ24314632
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GFRalpha1 is an essential receptor component for GDNF in the developing nervous system and kidneyQ24649094
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Enteric nervous system development: migration, differentiation, and diseaseQ26849660
A collagen VI-dependent pathogenic mechanism for Hirschsprung's diseaseQ27330447
SOX10 mutations in chronic intestinal pseudo-obstruction suggest a complex physiopathological mechanismQ28218691
Neurturin shares receptors and signal transduction pathways with glial cell line-derived neurotrophic factor in sympathetic neuronsQ28241378
Interneuron migration from basal forebrain to neocortex: dependence on Dlx genesQ28251621
Mice lacking Dlx1 show subtype-specific loss of interneurons, reduced inhibition and epilepsyQ28260777
Dlx transcription factors promote migration through repression of axon and dendrite growthQ28307110
Neonatal lethality in knockout mice expressing the kinase-dead form of the gefitinib target GAK is caused by pulmonary dysfunctionQ28477465
Mice lacking ZFHX1B, the gene that codes for Smad-interacting protein-1, reveal a role for multiple neural crest cell defects in the etiology of Hirschsprung disease-mental retardation syndromeQ28508181
Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second archesQ28588808
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limma powers differential expression analyses for RNA-sequencing and microarray studiesQ29617988
Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor RetQ29620364
Vitamin A facilitates enteric nervous system precursor migration by reducing Pten accumulationQ30493327
voom: Precision weights unlock linear model analysis tools for RNA-seq read countsQ33741687
Differential regional and subtype-specific vulnerability of enteric neurons to mitochondrial dysfunctionQ34081771
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Optimization of Laser-Capture Microdissection for the Isolation of Enteric Ganglia from Fresh-Frozen Human TissueQ89472389
Down syndrome mouse models have an abnormal enteric nervous systemQ93176238
Genetic background impacts developmental potential of enteric neural crest-derived progenitors in the Sox10Dom model of Hirschsprung disease.Q34211976
Expression level of Hand2 affects specification of enteric neurons and gastrointestinal function in miceQ35154143
Enteric neuron imbalance and proximal dysmotility in ganglionated intestine of the Sox10Dom/+ Hirschsprung mouse model.Q35234669
Essential roles of enteric neuronal serotonin in gastrointestinal motility and the development/survival of enteric dopaminergic neuronsQ35639931
Differential gene expression and functional analysis implicate novel mechanisms in enteric nervous system precursor migration and neuritogenesis.Q35950365
Gastrointestinal dysfunction in mice with a targeted mutation in the gene encoding vasoactive intestinal polypeptide: a model for the study of intestinal ileus and Hirschsprung's diseaseQ36093506
Dlx1&2-dependent expression of Zfhx1b (Sip1, Zeb2) regulates the fate switch between cortical and striatal interneuronsQ36540991
Emerging neuropeptide targets in inflammation: NPY and VIPQ36923640
Bone morphogenetic protein regulation of enteric neuronal phenotypic diversity: relationship to timing of cell cycle exitQ36992083
Hirschsprung-like disease is exacerbated by reduced de novo GMP synthesis.Q37259273
Chronic intestinal pseudo-obstruction related to viral infectionsQ37695810
Cleft palate defect of Dlx1/2-/- mutant mice is caused by lack of vertical outgrowth in the posterior palateQ37705822
Balancing on the crest - Evidence for disruption of the enteric ganglia via inappropriate lineage segregation and consequences for gastrointestinal functionQ38078731
A comparison of Illumina and Ion Torrent sequencing platforms in the context of differential gene expressionQ38630198
Mouse models of Hirschsprung disease and other developmental disorders of the enteric nervous system: Old and new playersQ38883845
Enteric neuropathies: Yesterday, Today and Tomorrow.Q38886424
A Novel Partial Duplication of ZEB2 and Review of ZEB2 Involvement in Mowat-Wilson SyndromeQ39424387
The timing and location of glial cell line-derived neurotrophic factor expression determine enteric nervous system structure and function.Q39562120
Retinaldehyde dehydrogenase enzymes regulate colon enteric nervous system structure and functionQ42077729
GABAergic Interneuron Differentiation in the Basal Forebrain Is Mediated through Direct Regulation of Glutamic Acid Decarboxylase Isoforms by Dlx Homeobox Transcription Factors.Q42513830
Short-chain fatty acids regulate the enteric neurons and control gastrointestinal motility in ratsQ43163542
The first intestinal motility patterns in fetal mice are not mediated by neurons or interstitial cells of Cajal.Q43168375
Mutations of the homeobox genes Dlx-1 and Dlx-2 disrupt the striatal subventricular zone and differentiation of late born striatal neurons.Q45932668
Neurochemical classification of enteric neurons in the guinea-pig distal colonQ46142578
VPAC1 receptors regulate intestinal secretion and muscle contractility by activating cholinergic neurons in guinea pig jejunum.Q46228789
Dlx1 and Dlx2 Promote Interneuron GABA Synthesis, Synaptogenesis, and Dendritogenesis.Q46708946
Dual origin of enteric neurons in vagal Schwann cell precursors and the sympathetic neural crest.Q48112709
Hirschsprung disease - integrating basic science and clinical medicine to improve outcomesQ50196075
Testing the Ret and Sema3d genetic interaction in mouse enteric nervous system development.Q51089610
Role of Dlx-1 and Dlx-2 genes in patterning of the murine dentition.Q51099851
Genetic interaction between Sox10 and Zfhx1b during enteric nervous system development.Q51854582
Muscularis macrophage development in the absence of an enteric nervous system.Q52718716
Current status of intestinal transplantationQ56987355
Loss of Tbx3 in murine neural crest reduces enteric glia and causes cleft palate, but does not influence heart development or bowel transitQ57186379
Unexpected Roles for the Second Brain: Enteric Nervous System as Master Regulator of Bowel FunctionQ58086437
RET signaling is essential for migration, axonal growth and axon guidance of developing sympathetic neuronsQ74756232
Chronic Intestinal Pseudo-obstructionQ87901875
P4510describes a project that usesImageJQ1659584
P433issue4
P577publication date2020-02-27
P1433published inJCI insightQ27727187
P1476titleDlx1/2 mice have abnormal enteric nervous system function
P478volume5

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