Effect of Botulinum Toxin A on Bladder Pain-Molecular Evidence and Animal Studies

scientific article published on 03 February 2020

Effect of Botulinum Toxin A on Bladder Pain-Molecular Evidence and Animal Studies is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.3390/TOXINS12020098
P932PMC publication ID7076962
P698PubMed publication ID32028597

P50authorTing-Chun YehQ89578183
P2093author name stringHann-Chorng Kuo
Po-Cheng Chen
Yann-Rong Su
P2860cites workBotulinum Toxin as a Biological Weapon: Medical and Public Health ManagementQ23832736
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Botulinum neurotoxins A and E undergo retrograde axonal transport in primary motor neuronsQ27339199
Childhood symptoms and events in women with interstitial cystitis/painful bladder syndromeQ43366391
Neonatal urinary bladder inflammation produces adult bladder hypersensitivityQ43518401
Activation and sensitisation of low and high threshold afferent fibres mediated by P2X receptors in the mouse urinary bladderQ44013297
Urodynamic results and clinical outcomes with intradetrusor injections of onabotulinumtoxinA in a randomized, placebo-controlled dose-finding study in idiopathic overactive bladder.Q44045350
Up-regulation of P2X3 receptor during stretch of bladder urothelial cells from patients with interstitial cystitisQ44686684
Subcutaneous administration of botulinum toxin A reduces formalin-induced painQ44722571
Intravesical botulinum toxin a administration produces analgesia against acetic acid induced bladder pain responses in ratsQ45062115
OnabotulinumtoxinA significantly attenuates bladder afferent nerve firing and inhibits ATP release from the urothelium.Q45907261
Different antinociceptive effects of botulinum toxin type A in inflammatory and peripheral polyneuropathic rat models.Q45940311
Intravesical botulinum toxin A administration inhibits COX-2 and EP4 expression and suppresses bladder hyperactivity in cyclophosphamide-induced cystitis in ratsQ46566035
Botulinum toxin type a inhibits calcitonin gene-related peptide release from isolated rat bladderQ46741008
Botulinum toxin type A inhibits sensory neuropeptide release in rat bladder models of acute injury and chronic inflammationQ46816115
Immunohistochemical evidence suggests repeated intravesical application of botulinum toxin A injections may improve treatment efficacy of interstitial cystitis/bladder pain syndromeQ47194025
Efficacy and safety of onabotulinumtoxinA in patients with urinary incontinence due to neurogenic detrusor overactivity: a randomised, double-blind, placebo-controlled trialQ48621733
Pathomechanism of Interstitial Cystitis/Bladder Pain Syndrome and Mapping the Heterogeneity of DiseaseQ28079052
Botulinum Toxin as a Pain Killer: Players and Actions in AntinociceptionQ28084583
Regulation of calcitonin gene-related peptide secretion from trigeminal nerve cells by botulinum toxin type A: implications for migraine therapyQ28246355
Changes in urinary bladder neurotrophic factor mRNA and NGF protein following urinary bladder dysfunctionQ28370786
Effect of botulinum toxin A on urothelial-release of ATP and expression of SNARE targets within the urotheliumQ33671401
Neonatal bladder inflammation alters activity of adult rat spinal visceral nociceptive neuronsQ33743682
TRPA1 mediates bladder hyperalgesia in a mouse model of cystitisQ33758307
Pentosanpolysulfate inhibits mast cell histamine secretion and intracellular calcium ion levels: an alternative explanation of its beneficial effect in interstitial cystitisQ33924099
Contemporary management of lower urinary tract disease with botulinum toxin A: a systematic review of botox (onabotulinumtoxinA) and dysport (abobotulinumtoxinA).Q34202884
Lamina propria: the functional center of the bladder?Q34357069
The Role of the Mucosa in Normal and Abnormal Bladder FunctionQ34528370
Drug Insight: biological effects of botulinum toxin A in the lower urinary tractQ35057523
Visceral pain: the neurophysiological mechanismQ35164413
Botulinum toxin: mechanisms of actionQ36009295
Proposed mechanism for the efficacy of injected botulinum toxin in the treatment of human detrusor overactivity.Q36373708
Activation of extracellular signal-regulated protein kinase 5 is essential for cystitis- and nerve growth factor-induced calcitonin gene-related peptide expression in sensory neuronsQ36411493
Increased bladder permeability in interstitial cystitis/painful bladder syndromeQ36445359
MicroRNA-mediated GABA Aα-1 receptor subunit down-regulation in adult spinal cord following neonatal cystitis-induced chronic visceral pain in ratsQ36503179
Chronic prostatitis/chronic pelvic pain syndrome and interstitial cystitis: are they related?Q36576053
Botulinum toxin type A normalizes alterations in urothelial ATP and NO release induced by chronic spinal cord injuryQ36737852
Early in life bladder inflammation alters opioid peptide content in the spinal cord and bladder of adult female ratsQ36921219
Botulinum toxin treatment of cranial-cervical dystonia, spasmodic dysphonia, other focal dystonias and hemifacial spasmQ36939434
The nature of immune responses to urinary tract infectionsQ37050386
Animal models and their use in understanding lower urinary tract dysfunction.Q37739960
The afferent system and its role in lower urinary tract dysfunctionQ37871311
Contemporary management of the painful bladder: a systematic reviewQ37932774
Botulinum neurotoxin for pain management: insights from animal modelsQ37954278
Transient receptor potential channels in bladder functionQ38056773
Botulinum toxins: mechanisms of action, antinociception and clinical applicationsQ38084073
The use of botulinum toxin for the treatment of urologic pain.Q38139145
The long journey of botulinum neurotoxins into the synapseQ38561450
Current and potential urological applications of botulinum toxin A.Q38564108
Botulinum Neurotoxins: Biology, Pharmacology, and ToxicologyQ39207459
Temporal relationship of muscle weakness and pain reduction in subjects treated with botulinum toxin AQ39387872
125I-Labelled botulinum a neurotoxin: Pharmacokinetics in cats after intramuscular injectionQ39392708
Increased nerve growth factor in neurogenic overactive bladder and interstitial cystitis patientsQ39900595
Interaction of 125I-labeled botulinum neurotoxins with nerve terminals. I. Ultrastructural autoradiographic localization and quantitation of distinct membrane acceptors for types A and B on motor nervesQ41486002
Botulinum toxin type A reduces pain supersensitivity in experimental diabetic neuropathy: bilateral effect after unilateral injectionQ43177955
Bladder overactivity and hyperexcitability of bladder afferent neurons after intrathecal delivery of nerve growth factor in rats.Q50474899
TRPV1 is involved in stretch-evoked contractile changes in the rat autonomous bladder model: a study with piperine, a new TRPV1 agonist.Q50706971
Contractile mechanisms coupled to TRPA1 receptor activation in rat urinary bladder.Q50733695
Retrograde transport of radiolabelled botulinum neurotoxin type A to the CNS after intradetrusor injection in rats.Q51030193
Intrathecal administration of botulinum toxin type A improves urinary bladder function and reduces pain in rats with cystitis.Q54357961
Down regulation of vascular endothelial growth factor is associated with decreased inflammation after intravesical OnabotulinumtoxinA injections combined with hydrodistention for patients with interstitial cystitis--clinical results and immunohistocQ54505136
The Expanding Therapeutic Utility of Botulinum Neurotoxins.Q55105284
Botulinum Toxin for Central Neuropathic Pain.Q55498097
Sensor Mechanism and Afferent Signal Transduction of the Urinary Bladder: Special Focus on transient receptor potential Ion ChannelsQ57653248
Visceral PainQ58086445
Higher Neural Correlates in Patients with Multiple Sclerosis and Neurogenic Overactive Bladder Following Treatment with Intradetrusor Injection of OnabotulinumtoxinAQ60923153
Mechanisms Underlying Overactive Bladder and Interstitial Cystitis/Painful Bladder SyndromeQ60958347
TRP Channels as Lower Urinary Tract Sensory Targets.Q64915134
Intravesical botulinum toxin A injections plus hydrodistension can reduce nerve growth factor production and control bladder pain in interstitial cystitisQ66829551
Effects of Botulinum a Toxin on Detrusor-Sphincter Dyssynergia in Spinal Cord Injury PatientsQ68331136
Histamine content and mast cell count of detrusor muscle in patients with interstitial cystitis and other types of chronic cystitisQ71062449
Distribution of nitric oxide synthase-immunoreactive nerves and identification of the cellular targets of nitric oxide in guinea-pig and human urinary bladder by cGMP immunohistochemistryQ73118138
Sensitivity of embryonic rat dorsal root ganglia neurons to Clostridium botulinum neurotoxinsQ73426186
Botulinum-A toxin for treating detrusor hyperreflexia in spinal cord injured patients: a new alternative to anticholinergic drugs? Preliminary resultsQ74206910
Immunoneutralization of nerve growth factor in lumbosacral spinal cord reduces bladder hyperreflexia in spinal cord injured ratsQ78413122
Long-distance retrograde effects of botulinum neurotoxin AQ81006671
Lack of ultrastructural detrusor changes following endoscopic injection of botulinum toxin type a in overactive neurogenic bladderQ81018432
Differences in mast cell infiltration, E-cadherin, and zonula occludens-1 expression between patients with overactive bladder and interstitial cystitis/bladder pain syndromeQ83947318
Central origin of the antinociceptive action of botulinum toxin type AQ84518244
Self-maintenance of neurogenic inflammation contributes to a vicious cycle in skinQ85604678
Words of wisdom. Re: Intrathecal administration of botulinum toxin type a improves urinary bladder function and reduces pain in rats with cystitisQ86914779
Increased severity of inflammation correlates with elevated expression of TRPV1 nerve fibers and nerve growth factor on interstitial cystitis/bladder pain syndromeQ87155523
GAG replenishment therapy for bladder pain syndrome/interstitial cystitisQ90790254
The Botulinum Treatment of Neurogenic Detrusor Overactivity: The Double-Face of the NeurotoxinQ90946609
Using Botulinum Toxin A for Treatment of Interstitial Cystitis/Bladder Pain Syndrome-Possible Pathomechanisms and Practical IssuesQ91125877
Botulinum Neurotoxin A Intravesical Injections in Interstitial Cystitis/Bladder Painful Syndrome: A Systematic Review with Meta-AnalysisQ93078697
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue2
P921main subjectanti-inflammatory agentQ581996
neuromuscular agentsQ50430099
P577publication date2020-02-03
P1433published inToxinsQ15724569
P1476titleEffect of Botulinum Toxin A on Bladder Pain-Molecular Evidence and Animal Studies
P478volume12

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