scholarly article | Q13442814 |
P50 | author | Michael Ploug | Q39427971 |
Haydyn D Mertens | Q58205910 | ||
Gabriel Birrane | Q59611108 | ||
Thomas J.D. Jørgensen | Q63412829 | ||
P2093 | author name string | Stephen G Young | |
Gunilla Olivecrona | |||
Katrine Zinck Leth-Espensen | |||
Kristian K Kristensen | |||
Muthuraman Meiyappan | |||
P2860 | cites work | GPIHBP1 is responsible for the entry of lipoprotein lipase into capillaries | Q24338437 |
GPIHBP1 stabilizes lipoprotein lipase and prevents its inhibition by angiopoietin-like 3 and angiopoietin-like 4 | Q24338849 | ||
The angiopoietin-like proteins ANGPTL3 and ANGPTL4 inhibit lipoprotein lipase activity through distinct mechanisms | Q28118447 | ||
Angiopoietin-like protein 4 converts lipoprotein lipase to inactive monomers and modulates lipase activity in adipose tissue | Q28272732 | ||
Angiopoietin-like protein 4 inhibition of lipoprotein lipase: evidence for reversible complex formation | Q28296885 | ||
Human lipoprotein lipase: relationship of activity, heparin affinity, and conformation as studied with monoclonal antibodies | Q28624276 | ||
Multimerization of glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) and familial chylomicronemia from a serine-to-cysteine substitution in GPIHBP1 Ly6 domain | Q33888534 | ||
Lipoprotein lipase domain function. | Q34338487 | ||
EX1 hydrogen exchange and protein folding | Q35632716 | ||
Lipase maturation factor 1: a lipase chaperone involved in lipid metabolism | Q35784094 | ||
A molecular biology-based approach to resolve the subunit orientation of lipoprotein lipase | Q36151990 | ||
The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain. | Q36585939 | ||
Biochemistry and pathophysiology of intravascular and intracellular lipolysis | Q36708030 | ||
Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease | Q36851336 | ||
Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease | Q36988623 | ||
Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans. | Q37036119 | ||
Analysis of overlapped and noisy hydrogen/deuterium exchange mass spectra | Q37373776 | ||
GPIHBP1 and Lipoprotein Lipase, Partners in Plasma Triglyceride Metabolism | Q91586192 | ||
Structure of lipoprotein lipase in complex with GPIHBP1 | Q91897805 | ||
New insights into angiopoietin-like proteins in lipid metabolism and cardiovascular disease risk | Q92503344 | ||
Did evolution create a flexible ligand-binding cavity in the urokinase receptor through deletion of a plesiotypic disulfide bond? | Q92510521 | ||
Endoplasmic reticulum quality control in lipoprotein metabolism | Q92818571 | ||
Inhibition of Angiopoietin-Like Protein 3 With a Monoclonal Antibody Reduces Triglycerides in Hypertriglyceridemia | Q93049588 | ||
Calcium triggers folding of lipoprotein lipase into active dimers | Q38320722 | ||
Chylomicronaemia--current diagnosis and future therapies | Q38366873 | ||
Monoclonal antibodies that bind to the Ly6 domain of GPIHBP1 abolish the binding of LPL. | Q38729657 | ||
An Asymmetric Runaway Domain Swap Antithrombin Dimer as a Key Intermediate for Polymerization Revealed by Hydrogen/Deuterium-Exchange Mass Spectrometry. | Q38805219 | ||
GPIHBP1 and Plasma Triglyceride Metabolism | Q38835828 | ||
Emerging strategies of targeting lipoprotein lipase for metabolic and cardiovascular diseases | Q38988355 | ||
The GPIHBP1-LPL complex is responsible for the margination of triglyceride-rich lipoproteins in capillaries | Q39004975 | ||
Variants with large effects on blood lipids and the role of cholesterol and triglycerides in coronary disease | Q39804212 | ||
ANGPTL3 Deficiency and Protection Against Coronary Artery Disease | Q40254292 | ||
Apolipoprotein cii enhances hydrolysis of monoglycerides by lipoprotein lipase, but the effect is abolished by fatty acids | Q40266894 | ||
GPIHBP1 missense mutations often cause multimerization of GPIHBP1 and thereby prevent lipoprotein lipase binding. | Q41877871 | ||
A highly conserved motif within the NH2-terminal coiled-coil domain of angiopoietin-like protein 4 confers its inhibitory effects on lipoprotein lipase by disrupting the enzyme dimerization. | Q42178295 | ||
Fatty acids bind tightly to the N-terminal domain of angiopoietin-like protein 4 and modulate its interaction with lipoprotein lipase | Q42184230 | ||
The angiopoietin-like protein ANGPTL4 catalyzes unfolding of the hydrolase domain in lipoprotein lipase and the endothelial membrane protein GPIHBP1 counteracts this unfolding. | Q42355233 | ||
Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia | Q42535148 | ||
Lipoprotein lipase. Molecular model based on the pancreatic lipase x-ray structure: consequences for heparin binding and catalysis | Q42612557 | ||
Rapid subunit exchange in dimeric lipoprotein lipase and properties of the inactive monomer | Q45072791 | ||
Phospholipase activity of milk lipoprotein lipase | Q45236292 | ||
GPIHBP1 autoantibodies in a patient with unexplained chylomicronemia. | Q46503166 | ||
We FRET so You Don't Have To: New Models of the Lipoprotein Lipase Dimer | Q47206557 | ||
An enzyme-linked immunosorbent assay for measuring GPIHBP1 levels in human plasma or serum. | Q47288042 | ||
Angiopoietin-like 3 in lipoprotein metabolism | Q47688043 | ||
Transgenic angiopoietin-like (angptl)4 overexpression and targeted disruption of angptl4 and angptl3: regulation of triglyceride metabolism. | Q51512763 | ||
Studies on inactivation of lipoprotein lipase: role of the dimer to monomer dissociation. | Q52661682 | ||
Purification and characterization of human lipoprotein lipase and hepatic triglyceride lipase. Reactivity with monoclonal antibodies to hepatic triglyceride lipase. | Q54005021 | ||
Mapping of the epitope on lipoprotein lipase recognized by a monoclonal antibody (5D2) which inhibits lipase activity | Q57840170 | ||
Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis | Q61990260 | ||
Lipoprotein lipase is active as a monomer | Q64118093 | ||
Detection and characterization of the heterozygote state for lipoprotein lipase deficiency | Q69608002 | ||
Mutation of tryptophan residues in lipoprotein lipase. Effects on stability, immunoreactivity, and catalytic properties | Q71973560 | ||
Molecular modeling of the dimeric structure of human lipoprotein lipase and functional studies of the carboxyl-terminal domain | Q74786238 | ||
Detailed characterization of the binding site of the lipoprotein lipase-specific monoclonal antibody 5D2 | Q77609917 | ||
Novel mutations in the GPIHBP1 gene identified in 2 patients with recurrent acute pancreatitis | Q87320688 | ||
A disordered acidic domain in GPIHBP1 harboring a sulfated tyrosine regulates lipoprotein lipase | Q89093967 | ||
Syndecan-1 Mediates Sorting of Soluble Lipoprotein Lipase with Sphingomyelin-Rich Membrane in the Golgi Apparatus | Q90205234 | ||
Mapping the sites of the lipoprotein lipase (LPL)-angiopoietin-like protein 4 (ANGPTL4) interaction provides mechanistic insight into LPL inhibition | Q90784980 | ||
A lipoprotein lipase-GPI-anchored high-density lipoprotein-binding protein 1 fusion lowers triglycerides in mice: Implications for managing familial chylomicronemia syndrome | Q90910334 | ||
On the mechanism of angiopoietin-like protein 8 for control of lipoprotein lipase activity | Q91241822 | ||
P433 | issue | 8 | |
P304 | page(s) | 4337-4346 | |
P577 | publication date | 2020-02-07 | |
P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
P1476 | title | Unfolding of monomeric lipoprotein lipase by ANGPTL4: Insight into the regulation of plasma triglyceride metabolism | |
P478 | volume | 117 |