scholarly article | Q13442814 |
P356 | DOI | 10.1038/S41388-020-1190-Y |
P698 | PubMed publication ID | 32034309 |
P2093 | author name string | Hui Wang | |
Xiaoguang Li | |||
Jingquan Li | |||
Qian Ba | |||
Peizhan Chen | |||
Xiaohua Duan | |||
P2860 | cites work | Overexpression of HIPK2 circumvents the blockade of apoptosis in chemoresistant ovarian cancer cells | Q39994304 |
Daxx cooperates with the Axin/HIPK2/p53 complex to induce cell death. | Q40185421 | ||
Inactivating mutations of the Siah-1 gene in gastric cancer | Q40507412 | ||
Prognostic and predictive role of JWA and XRCC1 expressions in gastric cancer | Q42719698 | ||
p300-mediated acetylation increased the protein stability of HIPK2 and enhanced its tumor suppressor function | Q47154768 | ||
MicroRNA-222-3p associated with Helicobacter pylori targets HIPK2 to promote cell proliferation, invasion and inhibits apoptosis in gastric cancer. | Q47308506 | ||
HIPK2 inhibits cell metastasis and improves chemosensitivity in esophageal squamous cell carcinoma | Q50054226 | ||
BCCIPβ modulates the ribosomal and extraribosomal function of S7 through a direct interaction. | Q50998094 | ||
Downregulation of homeodomain-interacting protein kinase-2 contributes to bladder cancer metastasis by regulating Wnt signaling. | Q54353028 | ||
HIPK2 phosphorylates ΔNp63α and promotes its degradation in response to DNA damage. | Q54588191 | ||
MDM2-regulated degradation of HIPK2 prevents p53Ser46 phosphorylation and DNA damage-induced apoptosis. | Q55043548 | ||
The Role of Angiogenesis in Hepatocellular Carcinoma | Q57053754 | ||
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries | Q60142201 | ||
HIF-1alpha-mediated up-regulation of vascular endothelial growth factor, independent of basic fibroblast growth factor, is important in the switch to the angiogenic phenotype during early tumorigenesis | Q74292706 | ||
MicroRNA-197 induces epithelial-mesenchymal transition and invasion through the downregulation of HIPK2 in lung adenocarcinoma | Q88391236 | ||
Homeodomain-interacting protein kinase 2 suppresses proliferation and aerobic glycolysis via ERK/cMyc axis in pancreatic cancer | Q92740315 | ||
Exosomal miR-1229 derived from colorectal cancer cells promotes angiogenesis by targeting HIPK2 | Q92764374 | ||
Transcriptional regulation of hypoxia-inducible factor 1alpha by HIPK2 suggests a novel mechanism to restrain tumor growth | Q24319862 | ||
HIPK2 neutralizes MDM2 inhibition rescuing p53 transcriptional activity and apoptotic function | Q24338503 | ||
HIPK2 overexpression leads to stabilization of p53 protein and increased p53 transcriptional activity by decreasing Mdm2 protein levels | Q24563515 | ||
Sorafenib in advanced hepatocellular carcinoma | Q27861075 | ||
Hypoxia-inducible factor (HIF-1)alpha: its protein stability and biological functions | Q28251400 | ||
The global epidemiology of hepatocellular carcinoma: present and future | Q28654353 | ||
Homeodomain interacting protein kinase 2 promotes apoptosis by downregulating the transcriptional corepressor CtBP. | Q31014772 | ||
Identification and characterization of HIPK2 interacting with p73 and modulating functions of the p53 family in vivo | Q31046841 | ||
HIPK2 inhibits both MDM2 gene and protein by, respectively, p53-dependent and independent regulations. | Q33292477 | ||
Downregulation of HIPK2 increases resistance of bladder cancer cell to cisplatin by regulating Wip1 | Q33638575 | ||
Prognostic Biomarker Identification Through Integrating the Gene Signatures of Hepatocellular Carcinoma Properties | Q33715750 | ||
Homeodomain-interacting protein kinase-2 mediates CtBP phosphorylation and degradation in UV-triggered apoptosis | Q33864038 | ||
Human homeodomain-interacting protein kinase-2 (HIPK2) is a member of the DYRK family of protein kinases and maps to chromosome 7q32-q34. | Q33928378 | ||
Verbascoside promotes apoptosis by regulating HIPK2-p53 signaling in human colorectal cancer | Q34340501 | ||
HIF-1α antagonizes p53-mediated apoptosis by triggering HIPK2 degradation. | Q34616703 | ||
Transcatheter arterial chemoembolization: history for more than 30 years. | Q34642418 | ||
HCC and angiogenesis: possible targets and future directions | Q35698574 | ||
Targeting COX-2/PGE(2) pathway in HIPK2 knockdown cancer cells: impact on dendritic cell maturation. | Q36380799 | ||
Apoptosis and autophagy: Regulation of apoptosis by DNA damage signalling - roles of p53, p73 and HIPK2. | Q37605156 | ||
Homeodomain-interacting protein kinase 2 (HIPK2): a promising target for anti-cancer therapies | Q37746347 | ||
Hepatocellular Carcinoma: Review of Epidemiology, Screening, Imaging Diagnosis, Response Assessment, and Treatment. | Q38483188 | ||
Heat shock modulates the subcellular localization, stability, and activity of HIPK2. | Q38786741 | ||
Targeting of tumour-infiltrating macrophages via CCL2/CCR2 signalling as a therapeutic strategy against hepatocellular carcinoma | Q38829170 | ||
MicroRNA-135a contributes to the development of portal vein tumor thrombus by promoting metastasis in hepatocellular carcinoma | Q39480218 | ||
Hypoxia suppresses chemotherapeutic drug-induced p53 Serine 46 phosphorylation by triggering HIPK2 degradation | Q39761954 | ||
Inhibition of HIF-1alpha activity by homeodomain-interacting protein kinase-2 correlates with sensitization of chemoresistant cells to undergo apoptosis. | Q39898008 | ||
An inducible autoregulatory loop between HIPK2 and Siah2 at the apex of the hypoxic response. | Q39910695 | ||
P433 | issue | 14 | |
P304 | page(s) | 2863-2876 | |
P577 | publication date | 2020-02-07 | |
P1433 | published in | Oncogene | Q1568657 |
P1476 | title | HIPK2 suppresses tumor growth and progression of hepatocellular carcinoma through promoting the degradation of HIF-1α | |
P478 | volume | 39 |
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