Axon micro-dissection and transcriptome profiling reveals the in vivo RNA content of fully differentiated myelinated motor axons

scientific article published on 12 February 2020

Axon micro-dissection and transcriptome profiling reveals the in vivo RNA content of fully differentiated myelinated motor axons is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1261/RNA.073700.119
P932PMC publication ID7161357
P698PubMed publication ID32051223

P50authorChristine HoltQ5111053
Joaquina FariasQ89685388
José Roberto Sotelo-SilveiraQ56440734
P2093author name stringJose Roberto Sotelo
P2860cites workCytoscape: a software environment for integrated models of biomolecular interaction networksQ24515682
Characterization of a novel peripheral nervous system myelin protein (PMP-22/SR13)Q24643599
Axonal microRNAs: localization, function and regulatory mechanism during axon developmentQ28076295
Compartmentalized Platforms for Neuro-Pharmacological ResearchQ28078426
Interplay between oxidant species and energy metabolismQ28383905
Myosin Va and kinesin II motor proteins are concentrated in ribosomal domains (periaxoplasmic ribosomal plaques) of myelinated axonsQ28572851
Myosin Va associates with mRNA in ribonucleoprotein particles present in myelinated peripheral axons and in the central nervous systemQ28583212
Ribosome assembly in eukaryotesQ29615231
STRING v10: protein-protein interaction networks, integrated over the tree of lifeQ29615545
Seeing the unseen: the hidden world of slow axonal transportQ30408406
Asymmetrical beta-actin mRNA translation in growth cones mediates attractive turning to netrin-1.Q30480161
Extracellular stimuli specifically regulate localized levels of individual neuronal mRNAs.Q30480550
Axoplasm isolation from peripheral nerveQ30494181
Data quality aware analysis of differential expression in RNA-seq with NOISeq R/Bioc packageQ30981058
Regulation of mitochondrial respiration by nitric oxide inhibition of cytochrome c oxidaseQ32139068
Subcellular profiling reveals distinct and developmentally regulated repertoire of growth cone mRNAs.Q33749248
mRNA coding for oxytocin is present in axons of the hypothalamo-neurohypophysial tractQ33811196
Exact and approximate area-proportional circular Venn and Euler diagramsQ33839132
Axonal transport proteomics reveals mobilization of translation machinery to the lesion site in injured sciatic nerveQ33855022
Ensembl BioMarts: a hub for data retrieval across taxonomic spaceQ33969847
HISAT: a fast spliced aligner with low memory requirementsQ34043398
The local transcriptome in the synaptic neuropil revealed by deep sequencing and high-resolution imagingQ34266527
Subcellular transcriptome alterations in a cell culture model of spinal muscular atrophy point to widespread defects in axonal growth and presynaptic differentiationQ34363918
StringTie enables improved reconstruction of a transcriptome from RNA-seq readsQ34463372
Novel zinc-based fixative for high quality DNA, RNA and protein analysisQ35891631
Whole transcriptome profiling reveals the RNA content of motor axonsQ36627858
Axonal mRNA in uninjured and regenerating cortical mammalian axonsQ36784476
Axon-Seq Decodes the Motor Axon Transcriptome and Its Modulation in Response to ALSQ60303934
Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in AxonsQ60912530
Cytoscape StringApp: Network Analysis and Visualization of Proteomics DataQ62004288
Ribosomal RNA in Mauthner axon: Implications for a protein synthesizing machinery in the myelinated axonQ66939879
Axoplasm architecture and physical properties as seen in the Myxicola giant axonQ67354542
Neurofilament mRNAs are present and translated in the normal and severed sciatic nerveQ72992851
Cryptic peripheral ribosomal domains distributed intermittently along mammalian myelinated axonsQ73168289
Diversity of mRNAs in the Axonal Compartment of Peptidergic Neurons in the RatQ74429598
Ribosomal distributions in axons of mammalian myelinated fibersQ80372786
Molecular control of local translation in axon development and maintenanceQ88086620
RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular TetherQ90191112
Rapid Cue-Specific Remodeling of the Nascent Axonal ProteomeQ90216864
On-Site Ribosome Remodeling by Locally Synthesized Ribosomal Proteins in AxonsQ91877804
Local protein synthesis is a ubiquitous feature of neuronal pre- and postsynaptic compartmentsQ92090130
Toward Axonal System Biology: Genome Wide Views of Local mRNA TranslationQ92310730
Atlas of Subcellular RNA Localization Revealed by APEX-SeqQ92967184
Dynamic Axonal Translation in Developing and Mature Visual CircuitsQ37059370
Transcript-level expression analysis of RNA-seq experiments with HISAT, StringTie and BallgownQ37275276
Organized ribosome-containing structural domains in axonsQ37366525
How common are extraribosomal functions of ribosomal proteins?Q37442012
The role of local protein synthesis and degradation in axon regenerationQ37516623
Disruption of axonal transport in motor neuron diseasesQ37982055
Glia to axon RNA transferQ38133483
Activation of oligodendroglial Fyn kinase enhances translation of mRNAs transported in hnRNP A2-dependent RNA granulesQ38517679
Axonal transport: The orderly motion of axonal structuresQ38705741
Axonal Localization of transgene mRNA in mature PNS and CNS neurons.Q38901693
ALS Along the Axons - Expression of Coding and Noncoding RNA Differs in Axons of ALS models.Q38903945
Origin of axonal proteins: Is the axon-schwann cell unit a functional syncytium?Q38918086
Compartmentalized Microfluidic Platforms: The Unrivaled Breakthrough of In Vitro Tools for Neurobiological Research.Q39010441
Global and local mechanisms sustain axonal proteostasis of transmembrane proteins.Q39145106
mRNA transport & local translation in neuronsQ39386342
Limited availability of ZBP1 restricts axonal mRNA localization and nerve regeneration capacity.Q39938284
Identification of locally synthesized proteins in proximal stump axons of the neurotomized hypoglossal nerveQ41038118
Axonal transport of neuropeptide encoding mRNAs within the hypothalamo-hypophyseal tract of ratsQ41082009
Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localizationQ41221866
RNA Docking and Local Translation Regulate Site-Specific Axon Remodeling In VivoQ41461256
The transcriptome of mouse central nervous system myelinQ41513628
RNA localization is a key determinant of neurite-enriched proteomeQ41701199
Gelatin in situ zymography on fixed, paraffin-embedded tissue: zinc and ethanol fixation preserve enzyme activityQ42054117
Zinc fixation preserves flow cytometry scatter and fluorescence parameters and allows simultaneous analysis of DNA content and synthesis, and intracellular and surface epitopes.Q42961216
Subcellular transcriptomics-dissection of the mRNA composition in the axonal compartment of sensory neuronsQ43618531
Expression of myelin protein genes in Schwann cellsQ45074898
Occurrence and sequence complexity of polyadenylated RNA in squid axoplasmQ45853388
Myelinated axons contain beta-actin mRNA and ZBP-1 in periaxoplasmic ribosomal plaques and depend on cyclic AMP and F-actin integrity for in vitro translation.Q46931498
To the end of the line: Axonal mRNA transport and local translation in health and neurodegenerative disease.Q47427810
Single-cell nanobiopsy reveals compartmentalization of mRNA in neuronal cells.Q47551003
Transcriptomic Analysis of Ribosome-Bound mRNA in Cortical Neurites In Vivo.Q47570626
Evaluation of local synthesis of axonal proteins in the goldfish Mauthner cell axon and axons of dorsal and ventral roots of the rat in vitroQ47818937
Demonstration of ion channel synthesis by isolated squid giant axon provides functional evidence for localized axonal membrane protein translationQ48112697
Localization of tyrosine hydroxylase mRNA in the axons of the hypothalamo-neurohypophysial systemQ48153016
Isolation of native Mauthner cell axoplasm and an analysis of organelle movement in non-aqueous and aqueous mediaQ48275230
Purification of Synaptosome Populations Using Fluorescence-Activated Synaptosome SortingQ48398593
An essential role for beta-actin mRNA localization and translation in Ca2+-dependent growth cone guidanceQ48419140
Cortical plaque-like structures identify ribosome-containing domains in the Mauthner cell axon.Q49116217
Eukaryotic ribosome assembly, transport and quality controlQ50206807
Heterogeneous Ribosomes Preferentially Translate Distinct Subpools of mRNAs Genome-wideQ50434557
Local and global influences on protein turnover in neurons and glia.Q55382071
Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractionsQ57471951
MitoMiner v4.0: an updated database of mitochondrial localization evidence, phenotypes and diseasesQ58608303
P4510describes a project that usesCytoscapeQ3699942
P921main subjectmyelinationQ14876135
P577publication date2020-02-12
P1433published inRNAQ7277164
P1476titleAxon micro-dissection and transcriptome profiling reveals the in vivo RNA content of fully differentiated myelinated motor axons

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