Not just a marker: CD34 on human hematopoietic stem/progenitor cells dominates vascular selectin binding along with CD44

scientific article published on 26 December 2017

Not just a marker: CD34 on human hematopoietic stem/progenitor cells dominates vascular selectin binding along with CD44 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1182/BLOODADVANCES.2017004317
P932PMC publication ID5745127
P698PubMed publication ID29296932

P50authorRachid SougratQ37376107
Jasmeen MerzabanQ57243246
Fajr AleisaQ85301292
Ayman AbuelelaQ88075896
Dina B AbuSamraQ89777778
Asma S Al-AmoodiQ89777781
Heba M Jalal AhmedQ89777784
P2093author name stringPtissam Bergam
Chee Jia Chin
P2860cites workThe CD34-related molecule podocalyxin is a potent inducer of microvillus formationQ21562330
Higher-affinity oligosaccharide ligands for E-selectinQ24292848
CD24, a mucin-type glycoprotein, is a ligand for P-selectin on human tumor cellsQ24317839
CD44 is a major E-selectin ligand on human hematopoietic progenitor cellsQ24679247
Quantitative Characterization of E-selectin Interaction with Native CD44 and P-selectin Glycoprotein Ligand-1 (PSGL-1) Using a Real Time Immunoprecipitation-based Binding Assay.Q27313560
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cellQ27861001
A cell initiating human acute myeloid leukaemia after transplantation into SCID miceQ28131777
Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to boneQ28264546
Regulation of PSGL-1 interactions with L-selectin, P-selectin, and E-selectin: role of human fucosyltransferase-IV and -VIIQ28296574
An Analysis of Trafficking Receptors Shows that CD44 and P-Selectin Glycoprotein Ligand-1 Collectively Control the Migration of Activated Human T-CellsQ29994863
Comparison of PSGL-1 microbead and neutrophil rolling: microvillus elongation stabilizes P-selectin bond clusters.Q30309150
'Slings' enable neutrophil rolling at high shearQ30422398
Direct observation of membrane tethers formed during neutrophil attachment to platelets or P-selectin under physiological flowQ30442037
Functional selectin ligands mediating human CD34(+) cell interactions with bone marrow endothelium are enhanced postnatally.Q30477605
In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftmentQ30484167
Neutrophil rolling at high shear: flattening, catch bond behavior, tethers and slingsQ30537790
Anti-CD44 antibodies inhibit both mTORC1 and mTORC2: a new rationale supporting CD44-induced AML differentiation therapy.Q30831849
Specific inhibition of P-selectin-mediated cell adhesion by phage display-derived peptide antagonistsQ30865755
The stem cell antigen CD34 functions as a regulator of hemopoietic cell adhesionQ33659589
TIM-1 glycoprotein binds the adhesion receptor P-selectin and mediates T cell trafficking during inflammation and autoimmunityQ33788812
Structural and functional features of the CD34 antigen: an update.Q34271080
Tyrosine sulfation of P-selectin glycoprotein ligand-1 is required for high affinity binding to P-selectinQ34295441
A sulfated peptide segment at the amino terminus of PSGL-1 is critical for P-selectin bindingQ34297510
CD34 and CD43 inhibit mast cell adhesion and are required for optimal mast cell reconstitutionQ34386926
A novel P-selectin glycoprotein ligand-1 monoclonal antibody recognizes an epitope within the tyrosine sulfate motif of human PSGL-1 and blocks recognition of both P- and L-selectin.Q34450761
Beyond mere markers: functions for CD34 family of sialomucins in hematopoiesisQ34529846
P-Selectin coated microtube for enrichment of CD34+ hematopoietic stem and progenitor cells from human bone marrowQ34714954
Novel functions of the CD34 familyQ34873662
Analysis of glycoprotein E-selectin ligands on human and mouse marrow cells enriched for hematopoietic stem/progenitor cellsQ35172452
Antigen CD34+ marrow cells engraft lethally irradiated baboonsQ35587124
Sialomucin CD34 is the major L-selectin ligand in human tonsil high endothelial venulesQ36236050
P-selectin glycoprotein ligand 1 is a ligand for L-selectin on neutrophils, monocytes, and CD34+ hematopoietic progenitor cellsQ36237566
Cell surface glycan engineering of neural stem cells augments neurotropism and improves recovery in a murine model of multiple sclerosisQ36251782
Lymphocyte homing into lymph nodes: in vitro demonstration of the selective affinity of recirculating lymphocytes for high-endothelial venulesQ36359810
Hematopoietic progenitor cell rolling in bone marrow microvessels: parallel contributions by endothelial selectins and vascular cell adhesion molecule 1.Q36401478
Identification of a specific glycoprotein ligand for P-selectin (CD62) on myeloid cellsQ36533177
miR-203 inhibits proliferation and self-renewal of leukemia stem cells by targeting survivin and Bmi-1.Q36548645
Endothelial selectins and vascular cell adhesion molecule-1 promote hematopoietic progenitor homing to bone marrowQ36735787
Modulation of Hematopoietic Chemokine Effects In Vitro and In Vivo by DPP-4/CD26.Q36806357
Fulfilling Koch's postulates in glycoscience: HCELL, GPS and translational glycobiologyQ36843250
Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species.Q36894740
Overlapping roles for endothelial selectins in murine hematopoietic stem/progenitor cell homing to bone marrowQ36980012
CD43 interferes with T-lymphocyte adhesionQ37039323
Immunophenotype and functional characteristics of human primitive CD34-negative hematopoietic stem cells: the significance of the intra-bone marrow injectionQ37075146
Glycoforms of human endothelial CD34 that bind L-selectin carry sulfated sialyl Lewis x capped O- and N-glycansQ37268934
Analysis of physiologic E-selectin-mediated leukocyte rolling on microvascular endotheliumQ37315488
Regulation of cell shape and adhesion by CD34.Q37521335
Dynamic alterations of membrane tethers stabilize leukocyte rolling on P-selectinQ37534814
Chlorate-induced inhibition of tyrosine sulfation on bone sialoprotein synthesized by a rat osteoblast-like cell line (UMR 106-01 BSP).Q38311005
A simple one-tube assay for immunophenotypical quantification of leukemic stem cells in acute myeloid leukemiaQ38956597
Therapeutic targeting of acute myeloid leukemia stem cellsQ39118867
The significance of integrin ligand nanopatterning on lipid raft clustering in hematopoietic stem cells.Q39407669
Hematopoietic progenitor cells and cellular microenvironment: behavioral and molecular changes upon interactionQ40409977
Ex vivo generation of CD34(+) cells from CD34(-) hematopoietic cellsQ40913687
Murine hematopoietic stem cell dormancy controlled by induction of a novel short form of PSF1 by histone deacetylase inhibitorsQ40987300
The cytoplasmic domain of stem cell antigen CD34 is essential for cytoadhesion signaling but not sufficient for proliferation signaling.Q41061917
Preferential adhesion of prostate cancer cells to a human bone marrow endothelial cell lineQ41068253
Characterization of a newly established human bone marrow endothelial cell line: distinct adhesive properties for hematopoietic progenitors compared with human umbilical vein endothelial cells.Q41142309
Primitive human hematopoietic progenitors adhere to P-selectin (CD62P).Q41335370
Western blot analysis of adhesive interactions under fluid shear conditions: the blot rolling assayQ41519698
Capture and enrichment of CD34-positive haematopoietic stem and progenitor cells from blood circulation using P-selectin in an implantable deviceQ41816291
Quantitative dynamic footprinting microscopy reveals mechanisms of neutrophil rollingQ42391293
Binding of L-Selectin to the Vascular Sialomucin CD34Q42805662
Constitutive expression of E-selectin and vascular cell adhesion molecule-1 on endothelial cells of hematopoietic tissues.Q42827719
PSGL-1 participates in E-selectin-mediated progenitor homing to bone marrow: evidence for cooperation between E-selectin ligands and alpha4 integrin.Q44451874
Relationship between selectin-mediated rolling of hematopoietic stem and progenitor cells and progression in hematopoietic developmentQ45864464
Rolling neutrophils form tethers and slings under physiologic conditions in vivo.Q45970808
Segregation of lipid raft markers including CD133 in polarized human hematopoietic stem and progenitor cells.Q47255313
Differences between the CD34+ and CD34- blast compartments in apoptosis resistance in acute myeloid leukemiaQ47915859
Analysis of primitive CD34- and CD34+ hematopoietic cells from adults: gain and loss of CD34 antigen by undifferentiated cells are closely linked to proliferative status in cultureQ48962505
CD34-negative hematopoietic stem cells show distinct expression profiles of homing molecules that limit engraftment in mice and sheep.Q50902000
The kinetic status of hematopoietic stem cell subpopulations underlies a differential expression of genes involved in self-renewal, commitment, and engraftment.Q50974629
Direct real-time observation of E- and P-selectin-mediated rolling on cutaneous lymphocyte-associated antigen immobilized on Western blots.Q52012675
Clinical significance of CD95, Bcl-2 and Bax expression and CD95 function in adult de novo acute myeloid leukemia in context of P-glycoprotein function, maturation stage, and cytogenetics.Q52975331
P-glycoprotein plays a drug-efflux-independent role in augmenting cell survival in acute myeloblastic leukemia and is associated with modulation of a sphingomyelin-ceramide apoptotic pathway.Q53410661
CD133-enriched CD34(-) (CD33/CD38/CD71)(-) cord blood cells acquire CD34 prior to cell division and hematopoietic activity is exclusively associated with CD34 expression.Q53538128
Signaling and induction of enhanced cytoadhesiveness via the hematopoietic progenitor cell surface molecule CD34.Q54213942
Kinetics of engraftment of CD34− and CD34+ cells from mobilized blood differs from that of CD34− and CD34+ cells from bone marrowQ56778045
Functional and kinetic characterization of granulocyte colony-stimulating factor-primed CD34- human stem cellsQ57002864
Human CD34+ cell preparations contain over 100-fold greater NOD/SCID mouse engrafting capacity than do CD34− cell preparationsQ57908338
The human B cell-associated antigen CD24 is a single chain sialoglycoproteinQ69993129
Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cellQ71142561
A functional comparison of CD34 + CD38- cells in cord blood and bone marrowQ71789381
PSGL-1-mediated adhesion of human hematopoietic progenitors to P-selectin results in suppression of hematopoiesisQ73065694
Reversible expression of CD34 by murine hematopoietic stem cellsQ73070185
Affinity and kinetic analysis of P-selectin binding to P-selectin glycoprotein ligand-1Q77604437
Reversibility of CD34 expression on human hematopoietic stem cells that retain the capacity for secondary reconstitutionQ78410368
SCID-repopulating cell activity of human cord blood-derived CD34- cells assured by intra-bone marrow injectionQ78654730
Modulation of hematopoietic stem cell homing and engraftment by CD26Q80450248
Influence of host irradiation on long-term engraftment by CD34-deficient hematopoietic stem cellsQ80651783
Forgotten gems: human CD34(-) hematopoietic stem cellsQ87088270
P433issue27
P304page(s)2799-2816
P577publication date2017-12-26
P1476titleNot just a marker: CD34 on human hematopoietic stem/progenitor cells dominates vascular selectin binding along with CD44
P478volume1

Reverse relations

cites work (P2860)
Q92959927Acute Myeloid and Lymphoblastic Leukemia Cell Interactions with Endothelial Selectins: Critical Role of PSGL-1, CD44 and CD43
Q92508814CD34 Identifies a Subset of Proliferating Microglial Cells Associated with Degenerating Motor Neurons in ALS
Q90543304Characterizing Glioblastoma Heterogeneity via Single-Cell Receptor Quantification
Q99403536GFc7 as a Smart Growth Nanofactor for ex vivo Expansion and Cryoprotection of Humans' Hematopoietic Stem Cells
Q58742303Influence of Modified Fucoidan and Related Sulfated Oligosaccharides on Hematopoiesis in Cyclophosphamide-Induced Mice
Q90114180The Impact of Cell-Expansion and Inflammation on The Immune-Biology of Human Adipose Tissue-Derived Mesenchymal Stromal Cells

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