Current understandings in treating children with steroid-resistant nephrotic syndrome

scientific article published on 21 February 2020

Current understandings in treating children with steroid-resistant nephrotic syndrome is …
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scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1007/S00467-020-04476-9
P698PubMed publication ID32086590

P50authorJun OhQ87932568
P2093author name stringJae Il Shin
Jiwon M Lee
Andreas Kronbichler
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Rituximab therapy in idiopathic membranous nephropathy: a 2-year studyQ34362660
Immunosuppression and renal outcome in congenital and pediatric steroid-resistant nephrotic syndromeQ34405386
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Effect of cyclosporin A on proteinuria in the course of glomerulopathy associated with WT1 mutationsQ34746123
Nephrotic syndrome in childhood.Q35207868
Treatment of steroid and cyclosporine-resistant idiopathic nephrotic syndrome in children.Q35226744
A phase 1, single-dose study of fresolimumab, an anti-TGF-β antibody, in treatment-resistant primary focal segmental glomerulosclerosisQ35669295
Efficacy of galactose and adalimumab in patients with resistant focal segmental glomerulosclerosis: report of the font clinical trial groupQ35704498
KANK deficiency leads to podocyte dysfunction and nephrotic syndromeQ35836132
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Rapid Response to Cyclosporin A and Favorable Renal Outcome in Nongenetic Versus Genetic Steroid-Resistant Nephrotic SyndromeQ36543103
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Cyclosporin A is superior to cyclophosphamide in children with steroid-resistant nephrotic syndrome-a randomized controlled multicentre trial by the Arbeitsgemeinschaft für Pädiatrische NephrologieQ37315097
Treatment of idiopathic FSGS with adrenocorticotropic hormone gel.Q37359035
ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruptionQ37384113
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The incidence of the nephrotic syndrome in childhood in GermanyQ38712759
Interventions for idiopathic steroid-resistant nephrotic syndrome in children.Q38801673
Nephrotoxicity in children with frequently relapsing nephrotic syndrome receiving long-term cyclosporine treatmentQ38854254
Targeting mTOR Signaling Can Prevent the Progression of FSGS.Q38922365
Steroid-resistant nephrotic syndrome: a persistent challenge for pediatric nephrologyQ38991259
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Effect of galactose on glomerular permeability and proteinuria in steroid-resistant nephrotic syndromeQ39398182
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Calcineurin Inhibitor Nephrotoxicity Through the Lens of Longitudinal Histology: Comparison of Cyclosporine and Tacrolimus ErasQ39680835
Calcineurin inhibitor induced nephrotoxicity in steroid resistant nephrotic syndromeQ39712811
Nephrotic syndrome in infants and children: pathophysiology and managementQ40039238
Direct effects of dexamethasone on human podocytesQ40256235
Epidemiology of idiopathic nephrotic syndrome in children: endemic or epidemic?Q40486811
Long-term outcome of idiopathic steroid-resistant nephrotic syndrome in childrenQ40579169
High incidence of idiopathic nephrotic syndrome in East Asian children: a nationwide survey in Japan (JP-SHINE study).Q40596186
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Response to cyclosporine in steroid-resistant nephrotic syndrome: discontinuation is possibleQ41027140
Mesenchymal Stem Cells May Ameliorate Nephrotic Syndrome Post-Allogeneic Hematopoietic Stem Cell Transplantation-Case ReportQ41417888
Low-dose synthetic adrenocorticotropic hormone-analog therapy for nephrotic patients: results from a single-center pilot study.Q41467613
Intravenous methylprednisolone and oral alkylating agent therapy of prednisone-resistant pediatric focal segmental glomerulosclerosis: a long-term follow-upQ42278929
Unsuccessful Treatment with Abatacept in Recurrent Focal Segmental Glomerulosclerosis after Kidney TransplantationQ42322601
B7-1 Blockade Does Not Improve Post-Transplant Nephrotic Syndrome Caused by Recurrent FSGS.Q42371173
Clinical and genetic heterogeneity in familial steroid-sensitive nephrotic syndromeQ42698311
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Mycophenolate mofetil therapy for children with steroid-resistant nephrotic syndromeQ43232395
Risk factors for cyclosporine-induced tubulointerstitial lesions in children with minimal change nephrotic syndromeQ43461510
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Intravenous cyclophosphamide in steroid-resistant nephrotic syndromeQ44407315
Allogeneic mesenchymal stem cell infusion for the stabilization of focal segmental glomerulosclerosis.Q44680239
Conversion from cyclosporine to tacrolimus improves quality-of-life indices, renal graft function and cardiovascular risk profileQ44899008
Efficacy of methylprednisolone pulse therapy in steroid-resistant nephrotic syndromeQ45025843
Sequential maintenance therapy with cyclosporin A and mycophenolate mofetil for sustained remission of childhood steroid-resistant nephrotic syndromeQ45230134
Switch from cyclosporine A to mycophenolate mofetil in nephrotic childrenQ45272404
FSGS permeability factor-associated nephrotic syndrome: remission after oral galactose therapyQ45757311
Partial remission with cyclosporine A in a patient with nephrotic syndrome due to NPHS2 mutation.Q45983340
Rapamycin for focal segmental glomerulosclerosis: a report of 3 casesQ46079811
Long-term outcome of idiopathic steroid-resistant nephrotic syndrome: a multicenter studyQ46091412
Efficacy and safety of tacrolimus versus cyclosporine in children with steroid-resistant nephrotic syndrome: a randomized controlled trialQ46096920
Complete remission of nephrotic syndrome in an infant with focal segmental glomerulosclerosis: is it renin-angiotensin blockade?Q46291457
A novel multidrug therapy for difficult cyclosporine-resistant focal segmental glomerulosclerosis.Q46299037
Ofatumumab in post-transplantation recurrence of a pediatric steroid-resistant idiopathic nephrotic syndrome.Q52640874
Long-Term Outcome of Steroid-Resistant Nephrotic Syndrome in Children.Q52838570
Ofatumumab in two pediatric nephrotic syndrome patients allergic to rituximab.Q52846398
Mycophenolate Mofetil Following Rituximab in Children With Steroid-Resistant Nephrotic Syndrome.Q52935578
Cyclophosphamide does not benefit patients with focal segmental glomerulosclerosis. A report of the International Study of Kidney Disease in Children.Q53365410
Mycophenolate mofetil is inferior to tacrolimus in sustaining remission in children with idiopathic steroid-resistant nephrotic syndrome.Q53421441
Levamisole treatment in steroid-sensitive and steroid-resistant nephrotic syndrome.Q54124424
Treatment of idiopathic nephrotic syndrome with cyclosporin A in children.Q54306616
Treatment of childhood prednisone-resistant nephrotic syndrome and focal segmental glomerulosclerosis with intravenous methylprednisolone and oral alkylating agents.Q54414448
Idiopathic nephrotic syndrome in childrenQ57176874
Rituximab Exhibits Altered Pharmacokinetics in Patients With Membranous NephropathyQ57180380
Sirolimus Therapy of Focal Segmental Glomerulosclerosis Is Associated With NephrotoxicityQ57691291
The role of B7-1 in proteinuria of glomerular originQ57701121
Management of steroid-resistant nephrotic syndrome in children and adolescentsQ57813728
DUET: A Phase 2 Study Evaluating the Efficacy and Safety of Sparsentan in Patients with FSGSQ58557086
The protective effects of rapamycin on cell autophagy in the renal tissues of rats with diabetic nephropathy via mTOR-S6K1-LC3II signaling pathwayQ58751244
Clinical course & management of childhood nephrotic syndrome in Germany: a large epidemiological ESPED studyQ61797780
Nephrotic Syndrome in South African Children: Changing Perspectives in the New MillenniumQ64226526
Efficacy of Mycophenolate Mofetil as a Remission Maintaining Agent in Idiopathic Childhood Nephrotic SyndromeQ64242663
Cyclophosphamide in steroid-sensitive nephrotic syndrome: outcome and outlookQ73402037
Long-term clinical and pathological effects of cyclosporin in children with nephrosisQ73639741
A prospective study on the use of mycophenolate mofetil in children with cyclosporine-dependent nephrotic syndromeQ79331373
Mycophenolate mofetil therapy for children with intractable nephrotic syndromeQ80110616
Treatment of idiopathic membranous nephropathy with the combination of steroids, tacrolimus and mycophenolate mofetil: results of a pilot studyQ80535367
Rituximab in patients with the steroid-resistant nephrotic syndromeQ80538441
A prospective, open-label trial of sirolimus in the treatment of focal segmental glomerulosclerosisQ80796893
Early coenzyme Q10 supplementation in primary coenzyme Q10 deficiencyQ81523690
Mycophenolate mofetil in treatment of childhood steroid-resistant nephrotic syndromeQ83406637
Use of sirolimus in patients with primary steroid-resistant nephrotic syndromeQ83904705
Effect of fosinopril in children with steroid-resistant idiopathic nephrotic syndromeQ83989262
Partial remission of resistant nephrotic syndrome after oral galactose therapyQ84220872
Mycophenolate mofetil for treatment of idiopathic nephrotic syndrome in childrenQ84971281
Three year outcome of childhood idiopathic nephrotic syndrome under a unified immunosuppressive protocolQ85317930
Rituximab treatment combined with methylprednisolone pulse therapy and immunosuppressants for childhood steroid-resistant nephrotic syndromeQ87240772
Survey of rituximab treatment for childhood-onset refractory nephrotic syndromeQ87423069
Ofatumumab for rituximab-resistant nephrotic syndromeQ87522692
Efficacy and safety of rituximab in children with difficult-to-treat nephrotic syndromeQ87572233
Late-onset adverse events after a single dose of rituximab in children with complicated steroid-dependent nephrotic syndromeQ89321513
Infrequent tacrolimus-induced nephrotoxicity in French patients with steroid-dependent nephrotic syndromeQ90084496
Rituximab therapy for refractory steroid-resistant nephrotic syndrome in childrenQ90626029
Exploring the Clinical and Genetic Spectrum of Steroid Resistant Nephrotic Syndrome: The PodoNet RegistryQ90677029
Levamisole for children with nephrotic syndrome: new evidence for the use of an "old" drugQ90868585
Molecular stratification of idiopathic nephrotic syndromeQ90951107
Industry Payments to Physician Specialists Who Prescribe Repository CorticotropinQ91057275
Cyclophosphamide versus cyclosporine A therapy in steroid-resistant nephrotic syndrome: a retrospective study with a mean 5-year follow-upQ91301517
Repository Corticotropin Versus Glucocorticoid for Nephrotic Syndrome: When Will We See the Evidence?Q91591677
High-Dose Rituximab and Early Remission in PLA2R1-Related Membranous NephropathyQ92152561
Rituximab for Children With Difficult-to-Treat Nephrotic Syndrome: Its Effects on Disease Progression and GrowthQ92652725
Efficacy and Safety of Sparsentan Compared With Irbesartan in Patients With Primary Focal Segmental Glomerulosclerosis: Randomized, Controlled Trial Design (DUET).Q46399341
Treatment of steroid-resistant focal segmental glomerulosclerosis with pulse methylprednisolone and alkylating agentsQ46519718
Galactose binds to focal segmental glomerulosclerosis permeability factor and inhibits its activityQ46566229
Combination of immunosuppressive agents in treatment of steroid-resistant minimal change disease and primary focal segmental glomerulosclerosisQ46694715
A Phase 2, Double-Blind, Placebo-Controlled, Randomized Study of Fresolimumab in Patients With Steroid-Resistant Primary Focal Segmental GlomerulosclerosisQ47155702
Treatment with tacrolimus and prednisolone is preferable to intravenous cyclophosphamide as the initial therapy for children with steroid-resistant nephrotic syndromeQ47417726
Whole Exome Sequencing of Patients with Steroid-Resistant Nephrotic SyndromeQ47615276
Genomic and clinical profiling of a national nephrotic syndrome cohort advocates a precision medicine approach to disease management.Q47997703
Further phenotypic heterogeneity of CoQ10 deficiency associated with steroid resistant nephrotic syndrome and novel COQ2 and COQ6 variantsQ48101924
Single infusion of low-dose ofatumumab in a child with complicated nephrotic syndrome with anti-rituximab antibodies.Q48106783
Ofatumumab for the treatment of childhood nephrotic syndrome.Q48221532
A randomized clinical trial indicates that levamisole increases the time to relapse in children with steroid-sensitive idiopathic nephrotic syndromeQ48570174
Steroid-resistant nephrotic syndrome: past and current perspectivesQ49500608
Adverse events linked with the use of chimeric and humanized anti-CD20 antibodies in children with idiopathic nephrotic syndrome.Q50047399
Trends and Characteristics of US Medicare Spending on Repository CorticotropinQ50155309
Efficacy and Safety of Cyclosporine versus Tacrolimus in Steroid and Cyclophosphamide Resistant Nephrotic Syndrome: A Prospective Study.Q50417540
Predictive factors for ciclosporin-associated nephrotoxicity in children with minimal change nephrotic syndrome.Q51486296
TRPC6 mutational analysis in a large cohort of patients with focal segmental glomerulosclerosis.Q51637426
Application of next-generation sequencing technology to diagnosis and treatment of focal segmental glomerulosclerosis.Q52561530
P921main subjectnephrotic syndromeQ504790
P577publication date2020-02-21
P1433published inPediatric NephrologyQ15749796
P1476titleCurrent understandings in treating children with steroid-resistant nephrotic syndrome

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