review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Kristina H Schmidt | |
Julius Muellner | |||
P2860 | cites work | The characterization of a mammalian DNA structure-specific endonuclease | Q24336672 |
Components of the secondary pathway stimulate the primary pathway of eukaryotic Okazaki fragment processing | Q24611034 | ||
An alternative pathway for Okazaki fragment processing: resolution of fold-back flaps by Pif1 helicase | Q24621929 | ||
DNA damage signalling prevents deleterious telomere addition at DNA breaks | Q24646336 | ||
Integrative analysis of the mitochondrial proteome in yeast | Q24793149 | ||
A yeast gene product, Fob1 protein, required for both replication fork blocking and recombinational hotspot activities | Q27929498 | ||
Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing | Q27929897 | ||
Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination. | Q27929966 | ||
The yeast Pif1p helicase removes telomerase from telomeric DNA. | Q27930167 | ||
Ubc9- and mms21-mediated sumoylation counteracts recombinogenic events at damaged replication forks | Q27930441 | ||
Telomerase-null survivor screening identifies novel telomere recombination regulators. | Q27930545 | ||
Rad53-Mediated Regulation of Rrm3 and Pif1 DNA Helicases Contributes to Prevention of Aberrant Fork Transitions under Replication Stress | Q27930928 | ||
Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork. | Q27931822 | ||
The Saccharomyces Pif1p DNA helicase and the highly related Rrm3p have opposite effects on replication fork progression in ribosomal DNA. | Q27932217 | ||
Pif1 family helicases suppress genome instability at G-quadruplex motifs | Q27932667 | ||
Migrating bubble during break-induced replication drives conservative DNA synthesis | Q27932674 | ||
The saccharomyces PIF1 DNA helicase inhibits telomere elongation and de novo telomere formation | Q27933419 | ||
A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery | Q27933727 | ||
The S. cerevisiae Rrm3p DNA helicase moves with the replication fork and affects replication of all yeast chromosomes | Q27934054 | ||
Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance | Q27935789 | ||
Sua5p a single-stranded telomeric DNA-binding protein facilitates telomere replication | Q27936111 | ||
The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria | Q27936543 | ||
Yeast two-hybrid analysis of the origin recognition complex of Saccharomyces cerevisiae: interaction between subunits and identification of binding proteins | Q27936544 | ||
Def1p is involved in telomere maintenance in budding yeast | Q27937231 | ||
Differential involvement of the related DNA helicases Pif1p and Rrm3p in mtDNA point mutagenesis and stability | Q27937429 | ||
Association of the yeast DNA helicase Pif1p with mitochondrial membranes and mitochondrial DNA. | Q27937683 | ||
A dynamic interface between vacuoles and mitochondria in yeast | Q27938276 | ||
A SUMO-like domain protein, Esc2, is required for genome integrity and sister chromatid cohesion in Saccharomyces cerevisiae. | Q27938418 | ||
Reconstituted Okazaki fragment processing indicates two pathways of primer removal | Q27938925 | ||
Saccharomyces Rrm3p, a 5' to 3' DNA helicase that promotes replication fork progression through telomeric and subtelomeric DNA. | Q27938991 | ||
RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex | Q27939442 | ||
Dna2p helicase/nuclease is a tracking protein, like FEN1, for flap cleavage during Okazaki fragment maturation | Q27939444 | ||
Pif1p helicase, a catalytic inhibitor of telomerase in yeast | Q27940134 | ||
The Tof1p-Csm3p protein complex counteracts the Rrm3p helicase to control replication termination of Saccharomyces cerevisiae | Q27940201 | ||
Identification of Saccharomyces cerevisiae Genes Whose Deletion Causes Synthetic Effects in Cells with Reduced Levels of the Nuclear Pif1 DNA Helicase | Q36383222 | ||
Translesion Polymerases Drive Microhomology-Mediated Break-Induced Replication Leading to Complex Chromosomal Rearrangements | Q36395769 | ||
Protein-RNA networks revealed through covalent RNA marks | Q36450070 | ||
Yeast Est2p affects telomere length by influencing association of Rap1p with telomeric chromatin | Q36498028 | ||
Mitochondrial retrograde signaling | Q36505532 | ||
Physical and functional interaction between yeast Pif1 helicase and Rim1 single-stranded DNA binding protein | Q36559279 | ||
Roles of Pif1-like helicases in the maintenance of genomic stability. | Q36578934 | ||
Yeast Helicase Pif1 Unwinds RNA:DNA Hybrids with Higher Processivity than DNA:DNA Duplexes. | Q36674709 | ||
Mrc1 is required for sister chromatid cohesion to aid in recombination repair of spontaneous damage | Q36701199 | ||
Global analysis of SUMO chain function reveals multiple roles in chromatin regulation | Q36732737 | ||
Proteomic and Genomic Analyses of the Rvb1 and Rvb2 Interaction Network upon Deletion of R2TP Complex Components | Q36745171 | ||
Translocation of Saccharomyces cerevisiae Pif1 helicase monomers on single-stranded DNA. | Q36783587 | ||
Pif1 is a force-regulated helicase | Q36914672 | ||
Flexibility of eukaryotic Okazaki fragment maturation through regulated strand displacement synthesis | Q36990200 | ||
Quantitative Analysis of Dynamic Protein Interactions during Transcription Reveals a Role for Casein Kinase II in Polymerase-associated Factor (PAF) Complex Phosphorylation and Regulation of Histone H2B Monoubiquitylation | Q37034347 | ||
Local chromatin structure at the ribosomal DNA causes replication fork pausing and genome instability in the absence of the S. cerevisiae DNA helicase Rrm3p | Q37092166 | ||
On helicases and other motor proteins | Q37105913 | ||
Break-induced replication: what is it and what is it for? | Q37138963 | ||
The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivo | Q37168915 | ||
Rrm3 protects the Saccharomyces cerevisiae genome from instability at nascent sites of retrotransposition | Q37260580 | ||
Requirement of Rrm3 helicase for repair of spontaneous DNA lesions in cells lacking Srs2 or Sgs1 helicase | Q37275472 | ||
G-quadruplex and G-rich sequence stimulate Pif1p-catalyzed downstream duplex DNA unwinding through reducing waiting time at ss/dsDNA junction. | Q37294862 | ||
pif mutation blocks recombination between mitochondrial rho+ and rho- genomes having tandemly arrayed repeat units in Saccharomyces cerevisiae | Q37347751 | ||
Telomerase is essential to alleviate pif1-induced replication stress at telomeres | Q37425005 | ||
Genetic and biochemical analyses of Pfh1 DNA helicase function in fission yeast | Q37483099 | ||
Pif1 helicase and Polδ promote recombination-coupled DNA synthesis via bubble migration. | Q37558760 | ||
Hrq1, a homolog of the human RecQ4 helicase, acts catalytically and structurally to promote genome integrity | Q37600384 | ||
Mitotic checkpoint function in the formation of gross chromosomal rearrangements in Saccharomyces cerevisiae | Q37619395 | ||
Diminished S-phase cyclin-dependent kinase function elicits vital Rad53-dependent checkpoint responses in Saccharomyces cerevisiae | Q37622853 | ||
A 3'-5' exonuclease activity embedded in the helicase core domain of Candida albicans Pif1 helicase | Q37652203 | ||
Periodic DNA patrolling underlies diverse functions of Pif1 on R-loops and G-rich DNA. | Q37723592 | ||
To peep into Pif1 helicase: multifaceted all the way from genome stability to repair-associated DNA synthesis | Q38185572 | ||
Genome-wide function of THO/TREX in active genes prevents R-loop-dependent replication obstacles | Q38254699 | ||
Control of translocations between highly diverged genes by Sgs1, the Saccharomyces cerevisiae homolog of the Bloom's syndrome protein | Q38406137 | ||
The intra-S phase checkpoint protein Tof1 collaborates with the helicase Rrm3 and the F-box protein Dia2 to maintain genome stability in Saccharomyces cerevisiae | Q34509237 | ||
Evidence suggesting that Pif1 helicase functions in DNA replication with the Dna2 helicase/nuclease and DNA polymerase delta | Q34520066 | ||
The amino terminus of the Saccharomyces cerevisiae DNA helicase Rrm3p modulates protein function altering replication and checkpoint activity | Q34569656 | ||
The Rad1-Rad10 complex promotes the production of gross chromosomal rearrangements from spontaneous DNA damage in Saccharomyces cerevisiae | Q34572779 | ||
RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase | Q34606774 | ||
The Pif1 family helicase Pfh1 facilitates telomere replication and has an RPA-dependent role during telomere lengthening | Q34614708 | ||
Sgs1 truncations induce genome rearrangements but suppress detrimental effects of BLM overexpression in Saccharomyces cerevisiae | Q34726553 | ||
Non-hexameric DNA helicases and translocases: mechanisms and regulation | Q34770065 | ||
A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation | Q34803778 | ||
The Pif1 family in prokaryotes: what are our helicases doing in your bacteria? | Q35041581 | ||
The absence of Top3 reveals an interaction between the Sgs1 and Pif1 DNA helicases in Saccharomyces cerevisiae | Q35083010 | ||
A parallel quadruplex DNA is bound tightly but unfolded slowly by pif1 helicase | Q35173001 | ||
Ultrafine anaphase bridges, broken DNA and illegitimate recombination induced by a replication fork barrier | Q35174775 | ||
G-quadruplexes significantly stimulate Pif1 helicase-catalyzed duplex DNA unwinding | Q35199422 | ||
Replisome function during replicative stress is modulated by histone h3 lysine 56 acetylation through Ctf4. | Q35342649 | ||
Break-induced replication requires DNA damage-induced phosphorylation of Pif1 and leads to telomere lengthening. | Q35347521 | ||
The essential Schizosaccharomyces pombe Pfh1 DNA helicase promotes fork movement past G-quadruplex motifs to prevent DNA damage | Q35486616 | ||
Suppression of spontaneous genome rearrangements in yeast DNA helicase mutants | Q35722229 | ||
Tight coevolution of proliferating cell nuclear antigen (PCNA)-partner interaction networks in fungi leads to interspecies network incompatibility | Q35787288 | ||
DNA replication through hard-to-replicate sites, including both highly transcribed RNA Pol II and Pol III genes, requires the S. pombe Pfh1 helicase. | Q35860068 | ||
Characterization of a highly conserved histone related protein, Ydl156w, and its functional associations using quantitative proteomic analyses | Q35878757 | ||
The Replisome-Coupled E3 Ubiquitin Ligase Rtt101Mms22 Counteracts Mrc1 Function to Tolerate Genotoxic Stress | Q35916165 | ||
Mrc1 is a replication fork component whose phosphorylation in response to DNA replication stress activates Rad53. | Q35966662 | ||
Integrated multi-omics analyses reveal the pleiotropic nature of the control of gene expression by Puf3p | Q36192515 | ||
A Novel Rrm3 Function in Restricting DNA Replication via an Orc5-Binding Domain Is Genetically Separable from Rrm3 Function as an ATPase/Helicase in Facilitating Fork Progression | Q36214221 | ||
A new role for Rrm3 in repair of replication-born DNA breakage by sister chromatid recombination | Q36364209 | ||
Systematic genetic analysis with ordered arrays of yeast deletion mutants | Q28131618 | ||
Okazaki fragment maturation in yeast. II. Cooperation between the polymerase and 3'-5'-exonuclease activities of Pol delta in the creation of a ligatable nick | Q28214427 | ||
Break-induced replication and recombinational telomere elongation in yeast | Q28244552 | ||
Alternative translation initiation augments the human mitochondrial proteome | Q28513778 | ||
Pfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome Integrity | Q28553990 | ||
Wss1 metalloprotease partners with Cdc48/Doa1 in processing genotoxic SUMO conjugates | Q28563890 | ||
Enzymes and reactions at the eukaryotic DNA replication fork | Q28610363 | ||
Saccharomyces cerevisiae Rrm3p DNA helicase promotes genome integrity by preventing replication fork stalling: viability of rrm3 cells requires the intra-S-phase checkpoint and fork restart activities | Q28776095 | ||
RPA prevents G-rich structure formation at lagging-strand telomeres to allow maintenance of chromosome ends | Q29147430 | ||
Global analysis of protein phosphorylation in yeast | Q29615057 | ||
DNA helicase Srs2 disrupts the Rad51 presynaptic filament | Q29618305 | ||
A DNA integrity network in the yeast Saccharomyces cerevisiae | Q29618912 | ||
Structure and mechanism of helicases and nucleic acid translocases | Q29620151 | ||
Tension directly stabilizes reconstituted kinetochore-microtubule attachments. | Q30500849 | ||
RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes | Q30704734 | ||
On the roles of Saccharomyces cerevisiae Dna2p and Flap endonuclease 1 in Okazaki fragment processing | Q31038690 | ||
DNA repair pathway selection caused by defects in TEL1, SAE2, and de novo telomere addition generates specific chromosomal rearrangement signatures. | Q31155502 | ||
Control of Rad52 recombination activity by double-strand break-induced SUMO modification | Q33259026 | ||
The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis | Q33285637 | ||
Sensitivity of yeast strains with long G-tails to levels of telomere-bound telomerase | Q33288733 | ||
Mph1p promotes gross chromosomal rearrangement through partial inhibition of homologous recombination | Q33347993 | ||
Post-replication repair suppresses duplication-mediated genome instability | Q33576739 | ||
PIF1 family DNA helicases suppress R-loop mediated genome instability at tRNA genes. | Q33628938 | ||
G-Quadruplex DNA Sequences Are Evolutionarily Conserved and Associated with Distinct Genomic Features in Saccharomyces cerevisiae | Q33646754 | ||
Yeast Sub1 and human PC4 are G-quadruplex binding proteins that suppress genome instability at co-transcriptionally formed G4 DNA | Q33741063 | ||
Selective ploidy ablation, a high-throughput plasmid transfer protocol, identifies new genes affecting topoisomerase I-induced DNA damage. | Q33776558 | ||
Quantitative fitness analysis shows that NMD proteins and many other protein complexes suppress or enhance distinct telomere cap defects. | Q33872233 | ||
Repair of chromosome ends after telomere loss in Saccharomyces | Q33948830 | ||
A gene with specific and global effects on recombination of sequences from tandemly repeated genes in Saccharomyces cerevisiae | Q33961850 | ||
The Pif1p subfamily of helicases: region-specific DNA helicases? | Q34134473 | ||
A genomewide screen for suppressors of Alu-mediated rearrangements reveals a role for PIF1 | Q34162595 | ||
Mitochondrial dysfunction due to oxidative mitochondrial DNA damage is reduced through cooperative actions of diverse proteins | Q34282032 | ||
Cell cycle-regulated oscillator coordinates core histone gene transcription through histone acetylation | Q34314464 | ||
Regulation of fragile sites expression in budding yeast by MEC1, RRM3 and hydroxyurea | Q34440200 | ||
Suppression of gross chromosomal rearrangements by yKu70-yKu80 heterodimer through DNA damage checkpoints | Q34478480 | ||
Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping. | Q34488378 | ||
Mms1 binds to G-rich regions in Saccharomyces cerevisiae and influences replication and genome stability | Q38768936 | ||
G-quadruplex-induced instability during leading-strand replication | Q38967736 | ||
De novo telomere formation is suppressed by the Mec1-dependent inhibition of Cdc13 accumulation at DNA breaks | Q39247578 | ||
The yeast and human FACT chromatin-reorganizing complexes solve R-loop-mediated transcription-replication conflicts | Q39422413 | ||
Gene function prediction from congruent synthetic lethal interactions in yeast | Q40510088 | ||
The interaction network of the chaperonin CCT | Q40987014 | ||
Intermediates of recombination during mating type switching in Saccharomyces cerevisiae | Q41203841 | ||
Impairment of replication fork progression mediates RNA polII transcription-associated recombination | Q41512551 | ||
A hybrid G-quadruplex structure formed between RNA and DNA explains the extraordinary stability of the mitochondrial R-loop | Q41517167 | ||
Yeast Hrq1 shares structural and functional homology with the disease-linked human RecQ4 helicase. | Q41693967 | ||
DNA replication through G-quadruplex motifs is promoted by the Saccharomyces cerevisiae Pif1 DNA helicase | Q41769196 | ||
The DNA helicase Pfh1 promotes fork merging at replication termination sites to ensure genome stability | Q41779826 | ||
Purification of nuclear poly(A)-binding protein Nab2 reveals association with the yeast transcriptome and a messenger ribonucleoprotein core structure | Q41810780 | ||
The conserved Mec1/Rad53 nuclear checkpoint pathway regulates mitochondrial DNA copy number in Saccharomyces cerevisiae | Q41835998 | ||
Highly transcribed RNA polymerase II genes are impediments to replication fork progression in Saccharomyces cerevisiae | Q41843323 | ||
Comprehensive and quantitative mapping of RNA-protein interactions across a transcribed eukaryotic genome | Q41900685 | ||
Essential Roles of the Smc5/6 Complex in Replication through Natural Pausing Sites and Endogenous DNA Damage Tolerance | Q42016964 | ||
Human Pif1 helicase unwinds synthetic DNA structures resembling stalled DNA replication forks | Q42129978 | ||
Pif1-family helicases cooperatively suppress widespread replication-fork arrest at tRNA genes | Q42323366 | ||
G-rich telomeric and ribosomal DNA sequences from the fission yeast genome form stable G-quadruplex DNA structures in vitro and are unwound by the Pfh1 DNA helicase | Q42324173 | ||
Oxidative DNA damage causes mitochondrial genomic instability in Saccharomyces cerevisiae | Q42839708 | ||
DNA Binding Induces Dimerization of Saccharomyces cerevisiae Pif1 | Q42925190 | ||
Escape of Sgs1 from Rad9 inhibition reduces the requirement for Sae2 and functional MRX in DNA end resection. | Q43192636 | ||
Histone H3 lysine 56 acetylation by Rtt109 is crucial for chromosome positioning | Q43243209 | ||
The Schizosaccharomyces pombe Pfh1p DNA helicase is essential for the maintenance of nuclear and mitochondrial DNA. | Q43251036 | ||
DNA helicase gene interaction network defined using synthetic lethality analyzed by microarray | Q43446083 | ||
ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones. | Q44079733 | ||
Saccharomyces cerevisiae RRM3, a 5' to 3' DNA helicase, physically interacts with proliferating cell nuclear antigen | Q44142880 | ||
Genetic separation of Sae2 nuclease activity from Mre11 nuclease functions in budding yeast | Q44205166 | ||
Mrc1 is required for normal progression of replication forks throughout chromatin in S. cerevisiae. | Q46025989 | ||
Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae | Q46062549 | ||
Loss of mitochondrial DNA under genotoxic stress conditions in the absence of the yeast DNA helicase Pif1p occurs independently of the DNA helicase Rrm3p. | Q46092453 | ||
Dna2 helicase/nuclease causes replicative fork stalling and double-strand breaks in the ribosomal DNA of Saccharomyces cerevisiae | Q46123466 | ||
The Saccharomyces cerevisiae helicase Rrm3p facilitates replication past nonhistone protein-DNA complexes | Q47303220 | ||
Replication Fork Reversal: Players and Guardians. | Q47315185 | ||
Genome-Wide Mapping of Decay Factor-mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4. | Q47381434 | ||
Cell cycle-dependent spatial segregation of telomerase from sites of DNA damage. | Q48241810 | ||
Cdc73 suppresses genome instability by mediating telomere homeostasis | Q48270215 | ||
Role of the Pif1-PCNA Complex in Pol δ-Dependent Strand Displacement DNA Synthesis and Break-Induced Replication | Q49994646 | ||
Missed cleavage opportunities by FEN1 lead to Okazaki fragment maturation via the long-flap pathway. | Q50113616 | ||
Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae | Q50351110 | ||
The Chromatin Remodeler ISW1 Is a Quality Control Factor that Surveys Nuclear mRNP Biogenesis. | Q50860853 | ||
Molecular mechanism of G-quadruplex unwinding helicase: sequential and repetitive unfolding of G-quadruplex by Pif1 helicase. | Q52655666 | ||
The role of Pif1p, a DNA helicase in Saccharomyces cerevisiae, in maintaining mitochondrial DNA. | Q54559833 | ||
SUMO E3 ligase Mms21 prevents spontaneous DNA damage induced genome rearrangements. | Q55068820 | ||
DNA-unwinding activity of Saccharomyces cerevisiae Pif1 is modulated by thermal stability, folding conformation, and loop lengths of G-quadruplex DNA | Q57284419 | ||
Proteomic profiling and functional characterization of post-translational modifications of the fission yeast RNA exosome | Q57469420 | ||
Pif1 helicase unfolding of G-quadruplex DNA is highly dependent on sequence and reaction conditions | Q57752886 | ||
The helicase Pif1 functions in the template switching pathway of DNA damage bypass | Q57752921 | ||
The Hrq1 and Pif1 DNA helicases synergistically modulate telomerase activity | Q57752983 | ||
Multiple Pif1 helicases are required to sequentially disrupt G-quadruplex structure and unwind duplex DNA | Q57754429 | ||
Pif1 is essential for efficient replisome progression through lagging strand G-quadruplex DNA secondary structures | Q58611626 | ||
A role for Mog1 in H2Bub1 and H3K4me3 regulation affecting RNAPII transcription and mRNA export | Q62019752 | ||
A Postincision-Deficient TFIIH Causes Replication Fork Breakage and Uncovers Alternative Rad51- or Pol32-Mediated Restart Mechanisms | Q63383451 | ||
The Helicase PIF1 Facilitates Resection over Sequences Prone to Forming G4 Structures | Q63383598 | ||
Pif1-Family Helicases Support Fork Convergence during DNA Replication Termination in Eukaryotes | Q64103307 | ||
The RecQ helicase Sgs1 drives ATP-dependent disruption of Rad51 filaments | Q64114343 | ||
Structural and functional analysis of the nucleotide and DNA binding activities of the human PIF1 helicase | Q64226601 | ||
Dynamic Processing of Displacement Loops during Recombinational DNA Repair | Q64387930 | ||
The finger subdomain of yeast telomerase cooperates with Pif1p to limit telomere elongation | Q80027637 | ||
Suppression of gross chromosomal rearrangements by the multiple functions of the Mre11-Rad50-Xrs2 complex in Saccharomyces cerevisiae | Q81615827 | ||
The amino-terminal TPR domain of Dia2 tethers SCF(Dia2) to the replisome progression complex | Q84901617 | ||
ATP Binding to Rad5 Initiates Replication Fork Reversal by Inducing the Unwinding of the Leading Arm and the Formation of the Holliday Junction | Q88615753 | ||
A Genome-Wide Screen Reveals a Role for the HIR Histone Chaperone Complex in Preventing Mislocalization of Budding Yeast CENP-A | Q90252034 | ||
Two Pif1 Family DNA Helicases Cooperate in Centromere Replication and Segregation in Saccharomyces cerevisiae | Q93159980 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 2 | |
P577 | publication date | 2020-02-20 | |
P1433 | published in | Genes | Q5532699 |
P1476 | title | Yeast Genome Maintenance by the Multifunctional PIF1 DNA Helicase Family | |
P478 | volume | 11 |