SLFN11 expression in advanced prostate cancer and response to platinum-based chemotherapy

scientific article published on 03 March 2020

SLFN11 expression in advanced prostate cancer and response to platinum-based chemotherapy is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1158/1535-7163.MCT-19-0926
P932PMC publication ID7440143
P698PubMed publication ID32127465

P50authorAndrea SbonerQ42869291
Scott T TagawaQ57622116
Vincenza ConteducaQ64495656
Panagiotis J VlachostergiosQ89611273
Megan SladeQ90008206
Michael SigourosQ90008225
Ryan DittamoreQ90008239
P2093author name stringDavid M Nanus
Himisha Beltran
Olivier Elemento
Juan Miguel Mosquera
Rohan Bareja
Sheng-Yu Ku
Luisa Fernandez
Judy Hess
Loredana Puca
P2860cites workCancer statistics, 2019Q90941571
Androgen receptor nuclear localization correlates with AR-V7 mRNA expression in circulating tumor cells (CTCs) from metastatic castration resistance prostate cancer patientsQ91583263
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Putative DNA/RNA helicase Schlafen-11 (SLFN11) sensitizes cancer cells to DNA-damaging agentsQ24297639
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Trial Design and Objectives for Castration-Resistant Prostate Cancer: Updated Recommendations From the Prostate Cancer Clinical Trials Working Group 3Q30277291
Multinational, double-blind, phase III study of prednisone and either satraplatin or placebo in patients with castrate-refractory prostate cancer progressing after prior chemotherapy: the SPARC trialQ33386511
RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance.Q34494714
Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response.Q35861427
SLFN11 inhibits checkpoint maintenance and homologous recombination repairQ35866775
Epigenetic inactivation of the putative DNA/RNA helicase SLFN11 in human cancer confers resistance to platinum drugsQ36772043
Platinum-based chemotherapy for variant castrate-resistant prostate cancerQ36977870
Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate CancerQ37179254
Association of AR-V7 on Circulating Tumor Cells as a Treatment-Specific Biomarker With Outcomes and Survival in Castration-Resistant Prostate CancerQ37550588
Resistance to PARP inhibitors by SLFN11 inactivation can be overcome by ATR inhibitionQ37684589
Commentary on "Integrative clinical genomics of advanced prostate cancer". Robinson D, Van Allen EM, Wu YM, Schultz N, Lonigro RJ, Mosquera JM, Montgomery B, Taplin ME, Pritchard CC, Attard G, Beltran H, Abida W, Bradley RK, Vinson J, Cao X, Vats P,Q38370247
Development and validation of a whole-exome sequencing test for simultaneous detection of point mutations, indels and copy-number alterations for precision cancer careQ38637891
Divergent clonal evolution of castration-resistant neuroendocrine prostate cancerQ38768101
Anti-tumour activity of platinum compounds in advanced prostate cancer-a systematic literature review.Q38800044
Combined Tumor Suppressor Defects Characterize Clinically Defined Aggressive Variant Prostate CancersQ39051337
Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis.Q40336402
PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer.Q40640808
The Initial Detection and Partial Characterization of Circulating Tumor Cells in Neuroendocrine Prostate CancerQ41566518
Proposed morphologic classification of prostate cancer with neuroendocrine differentiationQ41994427
Biallelic Inactivation of BRCA2 in Platinum-sensitive Metastatic Castration-resistant Prostate CancerQ42704874
Platinum sensitivity in metastatic prostate cancer: does histology matter?Q47195375
The association between germline BRCA2 variants and sensitivity to platinum-based chemotherapy among men with metastatic prostate cancer.Q47347786
EZH2 contributes to the response to PARP inhibitors through its PARP-mediated poly-ADP ribosylation in breast cancerQ48325256
Chemotherapy for Small Cell Carcinoma of Prostatic OriginQ48525082
Patient derived organoids to model rare prostate cancer phenotypes.Q55367999
Genomic Analysis of Three Metastatic Prostate Cancer Patients with Exceptional Responses to Carboplatin Indicating Different Types of DNA Repair DeficiencyQ57814257
Delta-like protein 3 expression and therapeutic targeting in neuroendocrine prostate cancerQ64073046
Randomized, Double-Blind, Phase II Study of Temozolomide in Combination With Either Veliparib or Placebo in Patients With Relapsed-Sensitive or Refractory Small-Cell Lung Cancer.Q64980716
Clinical features of neuroendocrine prostate cancerQ90124919
Integrative Molecular Analysis of Patients With Advanced and Metastatic CancerQ90583994
Single-Cell Analyses of Prostate Cancer Liquid Biopsies Acquired by ApheresisQ90858658
P577publication date2020-03-03
P1433published inMolecular Cancer TherapeuticsQ2363144
P1476titleSLFN11 expression in advanced prostate cancer and response to platinum-based chemotherapy

Reverse relations

Q99611471Impact of DNA damage repair defects and aggressive variant features on response to carboplatin-based chemotherapy in metastatic castration-resistant prostate cancercites workP2860

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