The enzymatic biosynthesis of acylated steroidal glycosides and their cytotoxic activity

scientific article published on 01 May 2018

The enzymatic biosynthesis of acylated steroidal glycosides and their cytotoxic activity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.APSB.2018.04.006
P932PMC publication ID6251810
P698PubMed publication ID30505666

P50authorJian-Qiang KongQ51706047
P2093author name stringMing Liu
P2860cites workCloning and functional expression of UGT genes encoding sterol glucosyltransferases from Saccharomyces cerevisiae, Candida albicans, Pichia pastoris, and Dictyostelium discoideumQ27936426
The lac operon galactoside acetyltransferaseQ28255835
Glycosyltransferases in plant natural product synthesis: characterization of a supergene family.Q30321076
Improved enzyme-mediated synthesis and supramolecular self-assembly of naturally occurring conjugates of β-sitosterol.Q31131916
Molecular cloning and biochemical characterization of a recombinant sterol 3-O-glucosyltransferase from Gymnema sylvestre R.Br. catalyzing biosynthesis of steryl glucosides.Q34177342
lac operon induction in Escherichia coli: Systematic comparison of IPTG and TMG induction and influence of the transacetylase LacA.Q34232148
Functional diversification of two UGT80 enzymes required for steryl glucoside synthesis in ArabidopsisQ34692577
Interactions among SARS-CoV accessory proteins revealed by bimolecular fluorescence complementation assay.Q36238605
The functions of steryl glycosides come to those who wait: Recent advances in plants, fungi, bacteria and animalsQ37688647
Sterol glycosyltransferases--the enzymes that modify sterolsQ37862116
Regioselective enzymatic acylation of complex natural products: expanding molecular diversityQ37892390
Therapeutic potential of cholesteryl O-acyl α-glucoside found in Helicobacter pyloriQ38039194
Immunological functions of steryl glycosidesQ38039373
Structure, bioactivity, and chemical synthesis of OSW-1 and other steroidal glycosides in the genus OrnithogalumQ38093270
Transcriptome-enabled discovery and functional characterization of enzymes related to (2S)-pinocembrin biosynthesis from Ornithogalum caudatum and their application for metabolic engineeringQ38267550
Steroids hydroxylation catalyzed by the monooxygenase mutant 139-3 from Bacillus megaterium BM3.Q38656209
Functional analyses of OcRhS1 and OcUER1 involved in UDP-L-rhamnose biosynthesis in Ornithogalum caudatum.Q39195412
cDNA Isolation and Functional Characterization of UDP-d-glucuronic Acid 4-Epimerase Family from Ornithogalum caudatumQ39195932
cDNA isolation and functional characterization of squalene synthase gene from Ornithogalum caudatumQ39304504
Transcriptome-guided gene isolation and functional characterization of UDP-xylose synthase and UDP-D-apiose/UDP-D-xylose synthase families from Ornithogalum caudatum Ait.Q39425498
Chaperone coexpression plasmids: differential and synergistic roles of DnaK-DnaJ-GrpE and GroEL-GroES in assisting folding of an allergen of Japanese cedar pollen, Cryj2, in Escherichia coliQ39560568
Structural analysis of novel bioactive acylated steryl glucosides in pre-germinated brown rice branQ46512960
A potent anti-complementary acylated sterol glucoside from Orostachys japonicusQ46715952
Metabolic engineering of Escherichia coli for 1-butanol production.Q46785830
Sterol 3β-glucosyltransferase biocatalysts with a range of selectivities, including selectivity for testosterone.Q50472414
Probing Steroidal Substrate Specificity of Cytochrome P450 BM3 Variants.Q51705948
Rice bran extract containing acylated steryl glucoside fraction decreases elevated blood LDL cholesterol level in obese Japanese men.Q53566973
Cytotoxic cholestane glycosides from the bulbs of Ornithogalum saundersiaeQ73423511
Synthesis of a cholestane glycoside OSW-1 with potent cytostatic activityQ74549108
First Total Synthesis of an Exceptionally Potent Antitumor Saponin, OSW-1Q74847068
Regioselective diversification of a cardiac glycoside, lanatoside C, by organocatalysisQ84747016
P433issue6
P304page(s)981-994
P577publication date2018-05-01
P1433published inActa Pharmaceutica Sinica BQ26854022
P1476titleThe enzymatic biosynthesis of acylated steroidal glycosides and their cytotoxic activity
P478volume8

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cites work (P2860)
Q64055635Characterization of two flavonol synthases with iron-independent flavanone 3-hydroxylase activity from Ornithogalum caudatum Jacq
Q64916842Combinatorial mutation on the β-glycosidase specific to 7-β-xylosyltaxanes and increasing the mutated enzyme production by engineering the recombinant yeast.
Q92922334OcUGT1-Catalyzing Glycodiversification of Steroids through Glucosylation and Transglucosylation Actions

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