Inflammation induces stress erythropoiesis through heme-dependent activation of SPI-C

scientific article published on 10 September 2019

Inflammation induces stress erythropoiesis through heme-dependent activation of SPI-C is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1126/SCISIGNAL.AAP7336
P932PMC publication ID6904953
P698PubMed publication ID31506384

P50authorPamela A Hankey-GiblinQ89301641
Laura F BennettQ90044356
Chang LiaoQ90044361
Beng San YeohQ90044364
Robert F PaulsonQ90044368
P2093author name stringMichael D Quickel
Matam Vijay-Kumar
K Sandeep Prabhu
P2860cites workThe tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysisQ22009936
Identification of a human heme exporter that is essential for erythropoiesisQ24304121
Characterization of growth-differentiation factor 15, a transforming growth factor beta superfamily member induced following liver injuryQ24554213
Heme regulates gene expression by triggering Crm1-dependent nuclear export of Bach1Q24563424
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidinQ24568204
Heme induces ubiquitination and degradation of the transcription factor Bach1Q24684849
Anemia: progress in molecular mechanisms and therapiesQ27023172
BMP4 and Madh5 regulate the erythroid response to acute anemiaQ28509763
Distinct roles for hepcidin and interleukin-6 in the recovery from anemia in mice injected with heat-killed Brucella abortusQ28510247
A mouse model of anemia of inflammation: complex pathogenesis with partial dependence on hepcidinQ28590264
Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated functionQ29617462
Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophagesQ33570011
Hypoxia regulates BMP4 expression in the murine spleen during the recovery from acute anemiaQ33619166
Murine erythroid short-term radioprotection requires a BMP4-dependent, self-renewing population of stress erythroid progenitorsQ34360122
Erythropoietin contrastingly affects bacterial infection and experimental colitis by inhibiting nuclear factor-κB-inducible immune pathwaysQ34544348
Innate immune activation during Salmonella infection initiates extramedullary erythropoiesis and splenomegalyQ35109868
Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishmentQ35113561
Clinical relevance and treatment of nonautoimmune anemia in chronic lymphocytic leukemiaQ35114910
Macrophages eat cancer cells using their own calreticulin as a guide: roles of TLR and Btk.Q35129097
In vitro culture of stress erythroid progenitors identifies distinct progenitor populations and analogous human progenitorsQ35171277
BMP4, SCF, and hypoxia cooperatively regulate the expansion of murine stress erythroid progenitorsQ35828707
Zymosan-induced generalized inflammation: experimental studies into mechanisms leading to multiple organ dysfunction syndromeQ36085578
Increased susceptibility to Salmonella infection in signal regulatory protein α-deficient miceQ36179550
LPS-induced down-regulation of signal regulatory protein {alpha} contributes to innate immune activation in macrophagesQ36229103
Toll-like receptor function and signalingQ36468530
Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewalQ36944727
Regulation of erythropoiesis by hypoxia-inducible factorsQ37063716
Maintenance of the BMP4-dependent stress erythropoiesis pathway in the murine spleen requires hedgehog signalingQ37071129
Cd47-Sirpα interaction and IL-10 constrain inflammation-induced macrophage phagocytosis of healthy self-cellsQ37264281
Role for Spi-C in the development of red pulp macrophages and splenic iron homeostasisQ37372755
Anemia in the ICU: anemia of chronic disease versus anemia of acute illnessQ38020058
Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1Q39645258
Iron, infections, and anemia of inflammationQ41632665
Erythropoietin stimulates spleen BMP4-dependent stress erythropoiesis and partially corrects anemia in a mouse model of generalized inflammation.Q42906357
Plasmodium chabaudi chabaudi infection in mice induces strong B cell responses and striking but temporary changes in splenic cell distributionQ43751346
Anemia of chronic disease in rheumatoid arthritis is associated with increased apoptosis of bone marrow erythroid cells: improvement following anti-tumor necrosis factor-alpha antibody therapyQ44045914
Tumor necrosis factor-alpha inhibits generation of glycophorin A+ cells by CD34+ cellsQ44210710
Disease-related anemia in chronic lymphocytic leukemia is not due to intrinsic defects of erythroid precursors: a possible pathogenetic role for tumor necrosis factor-alpha.Q45997397
An intronic sequence mutated in flexed-tail mice regulates splicing of Smad5.Q46865386
NF-κB regulates GDF-15 to suppress macrophage surveillance during early tumor development.Q47155954
Wave expansion of CD34+ progenitor cells in the spleen in rodent malariaQ47890009
Induction of an IL7-R(+)c-Kit(hi) myelolymphoid progenitor critically dependent on IFN-gamma signaling during acute malariaQ47940448
Chronic IFN-γ production in mice induces anemia by reducing erythrocyte life span and inhibiting erythropoiesis through an IRF-1/PU.1 axis.Q50530448
Reduced expression of CD47 during murine red blood cell (RBC) senescence and its role in RBC clearance from the circulation.Q50680745
A physiological model to study iron recycling in macrophages.Q50758548
Monocyte derived macrophages expand the murine stress erythropoietic niche during the recovery from anemiaQ57461481
Anemia of inflammationQ58605178
Tumor necrosis factor (TNF)-alpha directly inhibits human erythropoiesis in vitro: role of p55 and p75 TNF receptorsQ64008463
Fas antigen expression on CD34+ human marrow cells is induced by interferon gamma and tumor necrosis factor alpha and potentiates cytokine-mediated hematopoietic suppression in vitroQ71694018
TNF-related apoptosis-inducing ligand (TRAIL) as a negative regulator of normal human erythropoiesisQ73876962
Antihepcidin antibody treatment modulates iron metabolism and is effective in a mouse model of inflammation-induced anemiaQ82417395
Gdf15 regulates murine stress erythroid progenitor proliferation and the development of the stress erythropoiesis nicheQ92033378
P4510describes a project that usesImageJQ1659584
P433issue598
P577publication date2019-09-10
P1433published inScience SignalingQ7433604
P1476titleInflammation induces stress erythropoiesis through heme-dependent activation of SPI-C
P478volume12

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cites work (P2860)
Q92923667Interplay of Heme with Macrophages in Homeostasis and Inflammation
Q102048564Splenic erythroid progenitors decrease TNFα production by macrophages and reduce systemic inflammation in a mouse model of T cell-induced colitis
Q90189287Stress Erythropoiesis is a Key Inflammatory Response
Q101051148Stress erythropoiesis in atherogenic mice

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