| scholarly article | Q13442814 |
| P50 | author | Etienne Coyaud | Q56455448 |
| Amira Klip | Q64974771 | ||
| Javier R Jaldin-Fincati | Q80127566 | ||
| Logan K Townsend | Q89057928 | ||
| David C. Wright | Q89459465 | ||
| Scott Frendo-Cumbo | Q90083209 | ||
| Brian Raught | Q90083211 | ||
| P2093 | author name string | Ramnik J Xavier | |
| Nicolas J Pillon | |||
| Estelle M N Laurent | |||
| John Hunter Brumell | |||
| Joel M J Tan | |||
| P2860 | cites work | Update on the Kelch-like (KLHL) gene family | Q21245447 |
| The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1 | Q24300456 | ||
| A Cul3-based E3 ligase removes Aurora B from mitotic chromosomes, regulating mitotic progression and completion of cytokinesis in human cells | Q24307672 | ||
| The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradation | Q24315972 | ||
| LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing | Q24597817 | ||
| Endoplasmic reticulum stress and the inflammatory basis of metabolic disease | Q24633352 | ||
| BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates | Q27311670 | ||
| Function and regulation of cullin-RING ubiquitin ligases | Q28131707 | ||
| The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307) | Q28139056 | ||
| SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2 | Q28201656 | ||
| Insulin receptor substrate-1 associates with small nucleolar RNA which contributes to ribosome biogenesis | Q37615800 | ||
| Rac1 signalling towards GLUT4/glucose uptake in skeletal muscle. | Q37891215 | ||
| The Nrf2 cell defence pathway: Keap1-dependent and -independent mechanisms of regulation | Q38065567 | ||
| A current perspective of autophagosome biogenesis | Q38168065 | ||
| Autophagy in adipose tissue and the beta cell: implications for obesity and diabetes | Q38209287 | ||
| Transcriptional Dysregulation of Adipose Tissue Autophagy in Obesity | Q38851018 | ||
| Adiponectin stimulates autophagy and reduces oxidative stress to enhance insulin sensitivity during high-fat diet feeding in mice. | Q38970746 | ||
| Update on GLUT4 Vesicle Traffic: A Cornerstone of Insulin Action | Q39364864 | ||
| Molecular mechanism of insulin-induced degradation of insulin receptor substrate 1 | Q39677505 | ||
| Physical and functional interaction of sequestosome 1 with Keap1 regulates the Keap1-Nrf2 cell defense pathway | Q39717064 | ||
| Oxygen tension regulates the stability of insulin receptor substrate-1 (IRS-1) through caspase-mediated cleavage | Q40192622 | ||
| A Novel Domain Mediates Insulin-Induced Proteasomal Degradation of Insulin Receptor Substrate 1 (IRS-1) | Q41832780 | ||
| Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infection | Q41882233 | ||
| SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34 | Q42149699 | ||
| Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation | Q42529125 | ||
| Irs1 serine 307 promotes insulin sensitivity in mice | Q42563623 | ||
| Autophagy-mediated insulin receptor down-regulation contributes to endoplasmic reticulum stress-induced insulin resistance | Q42797937 | ||
| Control of cellular phosphatidylinositol 4,5-bisphosphate levels by adhesion signals and rho GTPases in NIH 3T3 fibroblasts involvement of both phosphatidylinositol-4-phosphate 5-kinase and phospholipase C. | Q42798810 | ||
| IRS1 degradation and increased serine phosphorylation cannot predict the degree of metabolic insulin resistance induced by oxidative stress | Q42801707 | ||
| Interplay of autophagy, receptor tyrosine kinase signalling and endocytic trafficking | Q47301172 | ||
| The NRF2-related interactome and regulome contain multifunctional proteins and fine-tuned autoregulatory loops. | Q47576030 | ||
| Autophagy is required to maintain muscle mass. | Q51411361 | ||
| Insulin uptake and action in microvascular endothelial cells of lymphatic and blood origin. | Q52672019 | ||
| Insulin-induced insulin receptor substrate-1 degradation is mediated by the proteasome degradation pathway. | Q52828725 | ||
| Low cellular IRS 1 gene and protein expression predict insulin resistance and NIDDM. | Q54069188 | ||
| Targeting autophagy in obesity: from pathophysiology to management | Q88447728 | ||
| Autophagy Differentially Regulates Insulin Production and Insulin Sensitivity | Q89091525 | ||
| Autophagy-Independent Functions of the Autophagy Machinery | Q92752249 | ||
| Autophagy Ablation in Adipocytes Induces Insulin Resistance and Reveals Roles for Lipid Peroxide and Nrf2 Signaling in Adipose-Liver Crosstalk | Q93074276 | ||
| Positive and negative regulation of insulin signaling through IRS-1 phosphorylation | Q28236905 | ||
| Autophagy and signaling: their role in cell survival and cell death | Q28278893 | ||
| Akt and Rac1 signaling are jointly required for insulin-stimulated glucose uptake in skeletal muscle and downregulated in insulin resistance | Q28301701 | ||
| AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1 | Q28506431 | ||
| FoxO3 controls autophagy in skeletal muscle in vivo | Q29614483 | ||
| TANDEM: matching proteins with tandem mass spectra | Q29615238 | ||
| Hepatic autophagy is suppressed in the presence of insulin resistance and hyperinsulinemia: inhibition of FoxO1-dependent expression of key autophagy genes by insulin | Q30434199 | ||
| A guided tour of the Trans-Proteomic Pipeline | Q30497827 | ||
| Serine/threonine phosphorylation of IRS-1 triggers its degradation: possible regulation by tyrosine phosphorylation | Q31809728 | ||
| ProteoWizard: open source software for rapid proteomics tools development | Q33349681 | ||
| Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant | Q33375721 | ||
| Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance. | Q33896647 | ||
| Insulin-like growth factor I-induced degradation of insulin receptor substrate 1 is mediated by the 26S proteasome and blocked by phosphatidylinositol 3'-kinase inhibition | Q33962150 | ||
| Trans-proteomic pipeline: a pipeline for proteomic analysis | Q34088315 | ||
| Listeria monocytogenes exploits efferocytosis to promote cell-to-cell spread. | Q34119441 | ||
| ProHits: integrated software for mass spectrometry-based interaction proteomics | Q34211917 | ||
| A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells | Q34260840 | ||
| Comet: an open-source MS/MS sequence database search tool | Q34311405 | ||
| Insulin signaling pathways in time and space. | Q34534983 | ||
| Defective hypothalamic autophagy directs the central pathogenesis of obesity via the IkappaB kinase beta (IKKbeta)/NF-kappaB pathway | Q35213340 | ||
| Autophagy mediates tolerance to Staphylococcus aureus alpha-toxin. | Q35356667 | ||
| Skeletal muscle myotubes in severe obesity exhibit altered ubiquitin-proteasome and autophagic/lysosomal proteolytic flux | Q35652814 | ||
| Insulin receptor substrate (IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidylinositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus | Q36111074 | ||
| Type 2 diabetes mellitus: a review of current trends | Q36299039 | ||
| Role of endoplasmic reticulum stress and c-Jun NH2-terminal kinase pathways in inflammation and origin of obesity and diabetes | Q36321560 | ||
| Tissue-specific roles of IRS proteins in insulin signaling and glucose transport | Q36386892 | ||
| Enhanced Nrf2 activity worsens insulin resistance, impairs lipid accumulation in adipose tissue, and increases hepatic steatosis in leptin-deficient mice. | Q36410781 | ||
| Identification of the degradation determinants of insulin receptor substrate 1 for signaling cullin-RING E3 ubiquitin ligase 7-mediated ubiquitination | Q36418948 | ||
| Non-autophagic roles of autophagy-related proteins | Q36594175 | ||
| Role of hypoxia in obesity-induced disorders of glucose and lipid metabolism in adipose tissue | Q37102864 | ||
| Beneficial effects of combined resveratrol and metformin therapy in treating diet-induced insulin resistance | Q37176719 | ||
| Ubiquitin ligase Cbl-b is a negative regulator for insulin-like growth factor 1 signaling during muscle atrophy caused by unloading. | Q37302235 | ||
| Insulin resistance and diabetes caused by genetic or diet-induced KBTBD2 deficiency in mice | Q37369378 | ||
| Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse | Q37376749 | ||
| P433 | issue | 44 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | autophagy | Q288322 |
| insulin resistance | Q1053470 | ||
| P304 | page(s) | 16172-16185 | |
| P577 | publication date | 2019-09-12 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Deficiency of the autophagy gene ATG16L1 induces insulin resistance through KLHL9/KLHL13/CUL3-mediated IRS1 degradation | |
| P478 | volume | 294 |
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