Ranolazine: Multifaceted Role beyond Coronary Artery Disease, a Recent Perspective

scientific article published on 01 July 2018

Ranolazine: Multifaceted Role beyond Coronary Artery Disease, a Recent Perspective is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4103/HEARTVIEWS.HEARTVIEWS_18_18
P932PMC publication ID6448470
P698PubMed publication ID31007857

P2093author name stringDhrubajyoti Bandyopadhyay
Raktim Kumar Ghosh
Ashish Aneja
Gopal Chandra Ghosh
Krishnarpan Chatterjee
P2860cites workRegulation of intracellular Na(+) in health and disease: pathophysiological mechanisms and implications for treatmentQ26863221
Pharmacology at work for cardio-oncology: ranolazine to treat early cardiotoxicity induced by antitumor drugsQ27006960
Effect of ranolazine on A1C and glucose levels in hyperglycemic patients with non-ST elevation acute coronary syndromeQ33872995
Inhibition of the late sodium current slows t-tubule disruption during the progression of hypertensive heart disease in the rat.Q33891370
Ranolazine effectively suppresses atrial fibrillation in the setting of heart failure.Q33916951
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Electrophysiological effects of ranolazine, a novel antianginal agent with antiarrhythmic propertiesQ34339876
Ranolazine: a new approach to treating an old problemQ34457675
Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina: a randomized controlled trialQ34544699
Anti-ischemic effects and long-term survival during ranolazine monotherapy in patients with chronic severe anginaQ34547211
Antianginal efficacy of ranolazine when added to treatment with amlodipine: the ERICA (Efficacy of Ranolazine in Chronic Angina) trialQ34569443
Sodium channel slow inactivation as a therapeutic target for myotonia congenitaQ35044306
Effect of Ranolazine Monotherapy on Glycemic Control in Subjects With Type 2 DiabetesQ35769527
Ranolazine in patients with incomplete revascularisation after percutaneous coronary intervention (RIVER-PCI): a multicentre, randomised, double-blind, placebo-controlled trialQ35810820
Ranolazine stabilizes cardiac ryanodine receptors: a novel mechanism for the suppression of early afterdepolarization and torsades de pointes in long QT type 2.Q35911288
Effects of ranolazine on exercise capacity, right ventricular indices, and hemodynamic characteristics in pulmonary arterial hypertension: a pilot studyQ36016535
Effect of ranolazine on left ventricular dyssynchrony in patients with coronary artery disease.Q36354376
Clinical pharmacokinetics of ranolazineQ36460838
Ranolazine versus amiodarone for prevention of postoperative atrial fibrillation.Q36534150
Reduced immunoreactivities of B-type natriuretic peptide in pulmonary arterial hypertension rats after ranolazine treatmentQ36760329
Ranolazine shortens repolarization in patients with sustained inward sodium current due to type-3 long-QT syndromeQ37038494
The Effects of Ranolazine on Paroxysmal Atrial Fibrillation in Patients with Coronary Artery Disease: A Preliminary Observational Study.Q37115123
Late sodium current inhibition as a new cardioprotective approachQ37156945
Pathophysiology of the cardiac late Na current and its potential as a drug targetQ37276416
Fibroblast growth factor 23 dysregulates late sodium current and calcium homeostasis with enhanced arrhythmogenesis in pulmonary vein cardiomyocytesQ37688345
Targeting fatty acid and carbohydrate oxidation--a novel therapeutic intervention in the ischemic and failing heart.Q37831555
Ranolazine in the prevention of anthracycline cardiotoxicity.Q38165595
Ranolazine treatment for myocardial infarction? Effects on the development of necrosis, left ventricular function and arrhythmias in experimental modelsQ38238926
Phase I safety study of ranolazine in pulmonary arterial hypertensionQ38398135
Effects of Ranolazine on Angina and Quality of Life After Percutaneous Coronary Intervention With Incomplete Revascularization: Results From the Ranolazine for Incomplete Vessel Revascularization (RIVER-PCI) TrialQ38400391
The HARMONY Trial: Combined Ranolazine and Dronedarone in the Management of Paroxysmal Atrial Fibrillation: Mechanistic and Therapeutic SynergismQ38407016
Combined actions of ivabradine and ranolazine reduce ventricular rate during atrial fibrillationQ38547436
Ranolazine preserves and improves left ventricular ejection fraction and autonomic measures when added to guideline-driven therapy in chronic heart failureQ38725641
Ranolazine Added to Amiodarone Facilitates Earlier Conversion of Atrial Fibrillation Compared to Amiodarone-Only Therapy.Q38969897
Role of Ranolazine in cardiovascular disease and diabetes: Exploring beyond anginaQ39006483
Ranolazine for rhythm control in atrial fibrillation: A systematic review and meta-analysisQ39006983
Ranolazine improves insulin resistance in non-diabetic patients with coronary heart disease. A pilot study.Q39669941
Blockade of Na+ channels in pancreatic α-cells has antidiabetic effectsQ42458638
Late sodium current inhibition reverses electromechanical dysfunction in human hypertrophic cardiomyopathyQ43741617
RAnoLazIne for the treatment of diastolic heart failure in patients with preserved ejection fraction: the RALI-DHF proof-of-concept studyQ44596273
Ranolazine enhances the antiarrhythmic activity of amiodarone by accelerating conversion of new-onset atrial fibrillation after cardiac surgeryQ44627954
Antiarrhythmic effects of ranolazine in a guinea pig in vitro model of long-QT syndromeQ44805574
Evaluation of ranolazine in patients with type 2 diabetes mellitus and chronic stable angina: results from the TERISA randomized clinical trial (Type 2 Diabetes Evaluation of Ranolazine in Subjects With Chronic Stable Angina).Q45038648
Atrial-ventricular differences in rabbit cardiac voltage-gated Na+ currents: Basis for atrial-selective block by ranolazineQ45070399
Use of ranolazine in patients with incomplete revascularization after percutaneous coronary intervention: design and rationale of the Ranolazine for Incomplete Vessel Revascularization Post-Percutaneous Coronary Intervention (RIVER-PCI) trialQ45195984
Ranolazine for the treatment of heart failure with preserved ejection fraction: background, aims, and design of the RALI-DHF studyQ45413079
Effect of ranolazine on glycaemic control in patients with type 2 diabetes treated with either glimepiride or metformin.Q45936839
Evaluation of the glycometabolic effects of ranolazine in patients with and without diabetes mellitus in the MERLIN-TIMI 36 randomized controlled trialQ46059602
Ranolazine increases β-cell survival and improves glucose homeostasis in low-dose streptozotocin-induced diabetes in miceQ46163409
Selective late INa inhibition by GS-458967 exerts parallel suppression of catecholamine-induced hemodynamically significant ventricular tachycardia and T-wave alternans in an intact porcine modelQ46432078
Ranolazine improves oxidative stress and mitochondrial function in the atrium of acetylcholine-CaCl2 induced atrial fibrillation ratsQ46544656
First direct comparison of the late sodium current blocker ranolazine to established antiarrhythmic agents in an ischemia/reperfusion modelQ48299852
The combined effects of ranolazine and dronedarone on human atrial and ventricular electrophysiologyQ48746789
Antiarrhythmic Effects of Combining Dofetilide and Ranolazine in a Model of Acutely Induced Atrial Fibrillation in Horses.Q49183821
Cardioprotective Effect of Ranolazine in the Process of Ischemia-reperfusion in Adult Rat CardiomyocytesQ50440240
Antiarrhythmic effects of ranolazine used both alone for prevention of atrial fibrillation and as an add-on to intravenous amiodarone for its pharmacological cardioversion: a meta-analysis.Q50652981
Ranolazine Prevents Phenotype Development in a Mouse Model of Hypertrophic Cardiomyopathy.Q50864373
Effects of ranolazine in a model of doxorubicin-induced left ventricle diastolic dysfunction.Q51093490
Effect of ranolazine in preventing postoperative atrial fibrillation in patients undergoing coronary revascularization surgery.Q51540903
Comparison of vernakalant and ranolazine in atrial fibrillation.Q51843072
Ranolazine in the treatment of atrial fibrillation: Results of the dose-ranging RAFFAELLO (Ranolazine in Atrial Fibrillation Following An ELectricaL CardiOversion) study.Q52870456
Long-term administration of ranolazine attenuates diastolic dysfunction and adverse myocardial remodeling in a model of heart failure with preserved ejection fraction.Q53608890
2013 ESC guidelines on the management of stable coronary artery diseaseQ57243329
Effects of ranolazine on left ventricular regional diastolic function in patients with ischemic heart diseaseQ72585308
A pilot study of ranolazine in patients with intermittent claudicationQ79429031
Effect of ranolazine, an antianginal agent with novel electrophysiological properties, on the incidence of arrhythmias in patients with non ST-segment elevation acute coronary syndrome: results from the Metabolic Efficiency With Ranolazine for LessQ81097337
[Management of refractory symptoms in hypertrophic cardiomyopathy with restrictive pathophysiology: novel perspectives for ranolazine]Q83864875
Comparison of effectiveness and safety of ranolazine versus amiodarone for preventing atrial fibrillation after coronary artery bypass graftingQ84501480
Ranolazine injection into coronary or femoral arteries exerts marked, transient regional vasodilation without systemic hypotension in an intact porcine modelQ85002021
Short-course of ranolazine prevents postoperative atrial fibrillation following coronary artery bypass grafting and valve surgeriesQ86038219
Ranolazine enhances the efficacy of amiodarone for conversion of recent-onset atrial fibrillationQ87183306
Ranolazine prevents INaL enhancement and blunts myocardial remodelling in a model of pulmonary hypertensionQ87623425
Open-label trial of ranolazine for the treatment of myotonia congenitaQ88525062
P433issue3
P921main subjectcoronary artery diseaseQ844935
P304page(s)88-98
P577publication date2018-07-01
P1433published inHeart ViewsQ15816937
P1476titleRanolazine: Multifaceted Role beyond Coronary Artery Disease, a Recent Perspective
P478volume19

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