Imaging Retinal Activity in the Living Eye

scientific article published on 01 September 2019

Imaging Retinal Activity in the Living Eye is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1146/ANNUREV-VISION-091517-034239
P932PMC publication ID7001891
P698PubMed publication ID31525142

P2093author name stringJennifer J Hunter
William H Merigan
Jesse B Schallek
P2860cites workFluorescent Proteins as Biomarkers and Biosensors: Throwing Color Lights on Molecular and Cellular ProcessesQ22241334
On the Regulation of the Blood-supply of the BrainQ24554227
Noninvasive two-photon imaging reveals retinyl ester storage structures in the eyeQ25255844
Functional optical coherence tomography enables in vivo physiological assessment of retinal rod and cone photoreceptors.Q27309050
Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogeneticsQ27676694
Optimized ratiometric calcium sensors for functional in vivo imaging of neurons and T lymphocytesQ27688085
Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus PhotographsQ27927580
Quantitative two-photon imaging of fluorescent biosensorsQ28083052
Spontaneous fluctuations in brain activity observed with functional magnetic resonance imagingQ28131817
Functional architecture of cortex revealed by optical imaging of intrinsic signalsQ28304727
Intracellular coenzymes as natural biomarkers for metabolic activities and mitochondrial anomaliesQ28397133
Brain magnetic resonance imaging with contrast dependent on blood oxygenationQ29618145
Imaging light responses of foveal ganglion cells in the living macaque eye.Q30426527
Oximetry of retinal vessels by dual-wavelength imaging: calibration and influence of pigmentationQ30473117
Pulsatility of parafoveal capillary leukocytesQ30488203
Scanning laser ophthalmoscope measurement of local fundus reflectance and autofluorescence changes arising from rhodopsin bleaching and regenerationQ30538620
Morphology and topography of retinal pericytes in the living mouse retina using in vivo adaptive optics imaging and ex vivo characterizationQ30560244
Independent optical excitation of distinct neural populationsQ30573493
Slow optical changes in human photoreceptors induced by light.Q30832723
Two-photon fluorescence spectroscopy and microscopy of NAD(P)H and flavoproteinQ30833030
Calcium signalling in Drosophila photoreceptors measured with GCaMP6f.Q41956896
THE INFLUENCE OF LIGHT ADAPTATION ON SUBSEQUENT DARK ADAPTATION OF THE EYE.Q42110939
Stable absolute flow estimation with Doppler OCT based on virtual circumpapillary scans.Q42158606
Retinal Oximetry and Vessel Diameter Measurements With a Commercially Available Scanning Laser Ophthalmoscope in Diabetic RetinopathyQ42631341
Use of the retinal vessel analyzer in ocular blood flow researchQ43291834
Retinal vessel oxygen saturation in healthy individuals.Q43955011
Functional organization of primate visual cortex revealed by high resolution optical imagingQ44538500
Cellular origin of intrinsic optical signals in the rabbit retinaQ46339098
Organization of the human trichromatic cone mosaic.Q46764062
Dynamic, in vivo, real-time detection of retinal oxidative status in a model of elevated intraocular pressure using a novel, reversibly responsive, profluorescent nitroxide probe.Q46807214
The elementary representation of spatial and color vision in the human retinaQ46837820
Analysis of visual pigment by fundus autofluorescence.Q46838958
Shift of intracellular chloride concentration in ganglion and amacrine cells of developing mouse retina.Q46863422
Two-photon imaging reveals somatodendritic chloride gradient in retinal ON-type bipolar cells expressing the biosensor ClomeleonQ46875094
Optical imaging to evaluate retinal activation by electrical currents using suprachoroidal-transretinal stimulationQ46979880
Non-invasive assessment of human cone photoreceptor function.Q47099707
Enhancement of intrinsic optical signal recording with split spectrum optical coherence tomographyQ47611551
Optophysiological Characterisation of Inner Retina Responses with High-Resolution Optical Coherence Tomography.Q47644861
Stimulus-induced changes of reflectivity detected by optical coherence tomography in macaque retinaQ47977396
Retinal Oximetry Discovers Novel Biomarkers in Retinal and Brain Diseases.Q48153621
Comparing retinal reflectance changes elicited by transcorneal electrical retinal stimulation with those of optic chiasma stimulation in catsQ48285401
The cost of cortical computationQ48360553
Sustained negative BOLD, blood flow and oxygen consumption response and its coupling to the positive response in the human brainQ48421460
Intrinsic signal imaging in macaque retina reveals different types of flash-induced light reflectance changes of different origins.Q50995818
Two-Photon Microscopy (TPM) and Fluorescence Lifetime Imaging Microscopy (FLIM) of Retinal Pigment Epithelium (RPE) of Mice In Vivo.Q51732391
The pathways of light measured in fundus reflectometry.Q52300848
All-optical recording and stimulation of retinal neurons in vivo in retinal degeneration mice.Q52621984
THE EFFECT OF PHOTOPIGMENT BLEACHING ON FUNDUS AUTOFLUORESCENCE IN ACUTE CENTRAL SEROUS CHORIORETINOPATHY.Q53064797
Test-retest reliability of retinal oxygen saturation measurement.Q53143674
Energy metabolism of rabbit retina as related to function: high cost of Na+ transportQ55036895
Interactions Between Electrical Activity and Cortical Microcirculation Revealed by Imaging Spectroscopy: Implications for Functional Brain MappingQ56524654
Full-field interferometric imaging of propagating action potentialsQ60045494
Functional architecture of the foveola revealed in the living primateQ60049685
Selective S Cone Damage and Retinal Remodeling Following Intense Ultrashort Pulse Laser Exposures in the Near-InfraredQ60309657
Correction-free remotely scanned two-photon mouse retinal imagingQ64218505
Measurements on fast light-induced light-scattering and -absorption changes in outer segments of vertebrate light sensitive rod cellsQ67808357
Rod densitometry in the aging human eyeQ67976401
Blood Flow and Oxygen Extraction in the Cat Uvea at Normal and High Intraocular PressuresQ71581728
In vivo measurement of the oxygen saturation of retinal vessels in healthy volunteersQ73305960
Measurement of the scotopic pigment in the living human eyeQ73882710
The difference spectrum and the photosensitivity of rhodopsin in the living human eyeQ74303231
The ionic movements during nervous activityQ75803610
Opacity changes in stimulated nerveQ80317518
Variability in bleach kinetics and amount of photopigment between individual foveal conesQ83984901
Studies of the retinal circulation in man. Observations on vessel diameter, arteriovenous oxygen difference, and mean circulation timeQ87019734
Volumetric imaging of rod and cone photoreceptor structure with a combined adaptive optics-optical coherence tomography-scanning laser ophthalmoscopeQ87974422
Cellular-scale evaluation of induced photoreceptor degeneration in the living primate eyeQ91668608
Changes in neuron structure during action potential propagation and synaptic transmissionQ39897836
Functional topography of rod and cone photoreceptors in macaque retina determined by retinal densitometryQ40026640
Oxidation-reduction ratio studies of mitochondria in freeze-trapped samples. NADH and flavoprotein fluorescence signalsQ40224778
Clinical applications of fundus reflection densitometryQ41128497
In vivo optical coherence tomography of stimulus-evoked intrinsic optical signals in mouse retinasQ41138739
Photoreceptor Layer Thickness Changes During Dark Adaptation Observed With Ultrahigh-Resolution Optical Coherence TomographyQ41157015
The spectral sensitivities of the middle- and long-wavelength-sensitive cones derived from measurements in observers of known genotypeQ41736458
Flicker evoked increase in optic nerve head blood flow in anesthetized catsQ41790504
In vivo optophysiology reveals that G-protein activation triggers osmotic swelling and increased light scattering of rod photoreceptors.Q41927712
Investigating the light absorption in a single pass through the photoreceptor layer by means of the lipofuscin fluorescenceQ41956801
Evaluating neural activity of retinal ganglion cells by flash-evoked intrinsic signal imaging in macaque retinaQ30844313
Special report: Noninvasive multi-parameter functional optical imaging of the eye.Q31145941
Oxygen distribution and consumption within the retina in vascularised and avascular retinas and in animal models of retinal diseaseQ31926355
Vascular imprints of neuronal activity: relationships between the dynamics of cortical blood flow, oxygenation, and volume changes following sensory stimulationQ32171911
Reduced response of retinal vessel diameters to flicker stimulation in patients with diabetesQ33203898
Mapping cone- and rod-induced retinal responsiveness in macaque retina by optical imagingQ33207427
Direct and noninvasive assessment of parafoveal capillary leukocyte velocityQ33226216
Intrinsic signals from human cone photoreceptorsQ33317460
Reflectometry with a scanning laser ophthalmoscopeQ33666573
Cortical functional architecture and local coupling between neuronal activity and the microcirculation revealed by in vivo high-resolution optical imaging of intrinsic signalsQ33736288
The arrangement of the three cone classes in the living human eye.Q33852770
Speed quantification and tracking of moving objects in adaptive optics scanning laser ophthalmoscopyQ33860090
All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsinsQ33983852
Regulation of blood flow in the retinal trilaminar vascular networkQ34067398
Functional magnetic resonance imaging of the retinaQ34175057
Co-registered optical coherence tomography and fluorescence molecular imaging for simultaneous morphological and molecular imagingQ34184267
Reduction of all-trans retinal to all-trans retinol in the outer segments of frog and mouse rod photoreceptorsQ34189493
Local flicker stimulation evokes local retinal blood velocity changesQ34290660
Dark adaptation and the retinoid cycle of visionQ34324524
Noninvasive imaging of mitochondrial dysfunction in dry age-related macular degenerationQ34347865
Monosynaptic circuit tracing in vivo through Cre-dependent targeting and complementation of modified rabies virus.Q34411033
Subcellular Imaging of Voltage and Calcium Signals Reveals Neural Processing In VivoQ34529761
New wrinkles in retinal densitometryQ34571764
Visual stimulus-induced changes in human near-infrared fundus reflectance.Q34654387
Blood Contrast Agents Enhance Intrinsic Signals in the Retina: Evidence for an Underlying Blood Volume ComponentQ35005986
Key enzymes of the retinoid (visual) cycle in vertebrate retinaQ35172750
MRI of blood flow of the human retinaQ35399550
Quantitative optical coherence tomography angiography of vascular abnormalities in the living human eyeQ35590370
In vivo confocal imaging of fast intrinsic optical signals correlated with frog retinal activationQ35673923
Imaging retinal densitometry with a confocal Scanning Laser OphthalmoscopeQ35757712
In Vivo Imaging of Retinal Oxidative Stress Using a Reactive Oxygen Species-Activated Fluorescent ProbeQ35766820
Characterizing the Human Cone Photoreceptor Mosaic via Dynamic Photopigment DensitometryQ35867597
In vivo optical imaging of physiological responses to photostimulation in human photoreceptorsQ36161032
Safety assessment in macaques of light exposures for functional two-photon ophthalmoscopy in humansQ36233207
Physiological features of the S- and M-cone photoreceptors of wild-type mice from single-cell recordingsQ36295638
Automatically tracking neurons in a moving and deforming brainQ36381478
Energy metabolism of the visual systemQ36448758
Laser Doppler measurements of blood flow in capillary tubes and retinal arteriesQ36523189
Laser Doppler measurements of blood velocity in human retinal vesselsQ36624737
Two-Photon Autofluorescence Imaging Reveals Cellular Structures Throughout the Retina of the Living Primate Eye.Q36630912
In Vivo Two-Photon Fluorescence Kinetics of Primate Rods and ConesQ36630929
Response of human retinal blood flow to light and darkQ36632074
Variations of blood flow at optic nerve head induced by sinusoidal flicker stimulation in catsQ36701896
Mechanism of voltage-sensitive fluorescence in a microbial rhodopsinQ36762452
Imaging light responses of retinal ganglion cells in the living mouse eye.Q36838386
Two-photon imaging of nonlinear glutamate release dynamics at bipolar cell synapses in the mouse retinaQ37032493
Retinal flavoprotein autofluorescence as a measure of retinal health.Q37106364
In Vivo Imaging of Retinal Hypoxia in a Model of Oxygen-Induced RetinopathyQ37153715
Label free measurement of retinal blood cell flux, velocity, hematocrit and capillary width in the living mouse eyeQ37404410
Photoreceptor disc shedding in the living human eye.Q37429119
Stimulus-evoked intrinsic optical signals in the retina: spatial and temporal characteristics.Q37546179
Stimulus-evoked intrinsic optical signals in the retina: pharmacologic dissection reveals outer retinal origins.Q37546183
Noninvasive functional imaging of the retina reveals outer retinal and hemodynamic intrinsic optical signal origins.Q37599628
Functional imaging using the retinal function imager: direct imaging of blood velocity, achieving fluorescein angiography-like images without any contrast agent, qualitative oximetry, and functional metabolic signalsQ37599631
Formation and Clearance of All-Trans-Retinol in Rods Investigated in the Living Primate Eye With Two-Photon OphthalmoscopyQ37616196
Excitatory synaptic inputs to mouse on-off direction-selective retinal ganglion cells lack direction tuning.Q37633620
Imaging an optogenetic pH sensor reveals that protons mediate lateral inhibition in the retinaQ37700959
Retinal intrinsic optical signals in a cat model of primary congenital glaucomaQ37718681
The cone-specific visual cycleQ37812794
Magnetic resonance imaging of the retina: from mice to menQ38110253
Functional hyperemia and mechanisms of neurovascular coupling in the retinal vasculatureQ38130441
Doppler optical coherence tomographyQ38202415
Intrinsic optical signal imaging of retinal physiology: a reviewQ38592719
In Vivo Imaging of Retinal Hypoxia Using HYPOX-4-Dependent Fluorescence in a Mouse Model of Laser-Induced Retinal Vein Occlusion (RVO).Q38650889
Voltage imaging with genetically encoded indicators.Q38688973
Rapid repeatable in vivo detection of retinal reactive oxygen speciesQ38731255
Optical measurement of membrane potentialQ39775337
P407language of work or nameEnglishQ1860
P304page(s)15-45
P577publication date2019-09-01
P1433published inAnnual Review of Vision ScienceQ27726601
P1476titleImaging Retinal Activity in the Living Eye
P478volume5

Search more.