Use of the Aptima mRNA high-risk human papillomavirus (HR-HPV) assay compared to a DNA HR-HPV assay in the English cervical screening programme: a decision tree model based economic evaluation

scientific article published on 08 March 2020

Use of the Aptima mRNA high-risk human papillomavirus (HR-HPV) assay compared to a DNA HR-HPV assay in the English cervical screening programme: a decision tree model based economic evaluation is …
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scholarly articleQ13442814

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P356DOI10.1136/BMJOPEN-2019-031303
P932PMC publication ID7064071
P698PubMed publication ID32152154

P50authorGeorgie WestonQ90168281
P2093author name stringChristina Founta
Maria Kyrgiou
Thomas Iftner
Elisabeth J Adams
Michael J Harvey
Caroline Dombrowski
P2860cites workImpact and Effectiveness of the Quadrivalent Human Papillomavirus Vaccine: A Systematic Review of 10 Years of Real-world ExperienceQ26745696
A review of the clinical performance of the Aptima HPV assayQ26776336
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Human papillomavirus oncogenic mRNA testing for cervical cancer screening: baseline and longitudinal results from the CLEAR studyQ30278853
APTIMA HPV assay performance in women with atypical squamous cells of undetermined significance cytology resultsQ30456309
Clinical performance of the APTIMA HPV Assay for the detection of high-risk HPV and high-grade cervical lesionsQ34995358
Head-to-Head Comparison of the RNA-Based Aptima Human Papillomavirus (HPV) Assay and the DNA-Based Hybrid Capture 2 HPV Test in a Routine Screening Population of Women Aged 30 to 60 Years in GermanyQ35868702
Human Papillomavirus Assays and Cytology in Primary Cervical Screening of Women Aged 30 Years and AboveQ35898888
Comparing the performance of six human papillomavirus tests in a screening populationQ36663594
Cervical cancer screening programmes and policies in 18 European countriesQ36695640
Rapid clearance of human papillomavirus and implications for clinical focus on persistent infectionsQ36994715
The association between knowledge of HPV and feelings of stigma, shame and anxiety.Q37006074
Short term persistence of human papillomavirus and risk of cervical precancer and cancer: population based cohort studyQ37281729
Guidelines for human papillomavirus DNA test requirements for primary cervical cancer screening in women 30 years and olderQ37461977
The Aptima HPV assay fulfills the cross-sectional clinical and reproducibility criteria of international guidelines for human papillomavirus test requirements for cervical screeningQ37470374
The APTIMA HPV assay versus the Hybrid Capture 2 test in triage of women with ASC-US or LSIL cervical cytology: a meta-analysis of the diagnostic accuracyQ38011639
Evidence regarding human papillomavirus testing in secondary prevention of cervical cancerQ38064070
Efficacy of HPV-based screening for prevention of invasive cervical cancer: follow-up of four European randomised controlled trialsQ38160099
Are 20 human papillomavirus types causing cervical cancer?Q38240044
The clinical effectiveness and cost-effectiveness of primary human papillomavirus cervical screening in England: extended follow-up of the ARTISTIC randomised trial cohort through three screening roundsQ38928159
Aptima HPV Assay versus Hybrid Capture® 2 HPV test for primary cervical cancer screening in the HPV FOCAL trialQ40405504
Factors associated with type-specific persistence of high-risk human papillomavirus infection: A population-based study.Q40664880
A daunting challenge: Human Papillomavirus assays and cytology in primary cervical screening of women below age 30yearsQ40933987
Evaluation of oncogenic human papillomavirus RNA and DNA tests with liquid-based cytology in primary cervical cancer screening: the FASE studyQ43769391
Transmission dynamic modelling of the impact of human papillomavirus vaccination in the United KingdomQ43961793
The longitudinal clinical performance of the RNA-based AHPV Human Papillomavirus (HPV) Assay in comparison to the DNA-based Hybrid Capture 2 HPV Test in 2 consecutive screening rounds with a 6-year interval in GermanyQ57792215
A 2‐Year Prospective Study of Human Papillomavirus Persistence among Women with a Cytological Diagnosis of Atypical Squamous Cells of Undetermined Significance or Low‐Grade Squamous Intraepithelial LesionQ58475803
Clinical Validation of the cobas HPV Test on the cobas 6800 System for the Purpose of Cervical ScreeningQ61806246
HPV testing for cervical cancer screening: technical improvement of laboratory logistics and good clinical performance of the cobas 6800 in comparison to the 4800 systemQ64054260
Comparative performance of human papillomavirus messenger RNA versus DNA screening tests at baseline and 48 months in the HPV FOCAL trialQ64136355
Primary cervical screening with high risk human papillomavirus testing: observational studyQ64232184
Management of women with abnormal cervical cytology: treatment patterns and associated costs in England and WalesQ80015292
ARTISTIC: a randomised trial of human papillomavirus (HPV) testing in primary cervical screeningQ84853922
HPV-mRNA and HPV-DNA detection in samples taken up to seven years before severe dysplasia of cervix uteriQ91039520
16/18 genotyping in triage of persistent human papillomavirus infections with negative cytology in the English cervical screening pilotQ92603332
P275copyright licenseCreative Commons Attribution-NonCommercial 4.0 InternationalQ34179348
P6216copyright statuscopyrightedQ50423863
P433issue3
P921main subjectdecision treeQ831366
P304page(s)e031303
P577publication date2020-03-08
P1433published inBMJ OpenQ17003470
P1476titleUse of the Aptima mRNA high-risk human papillomavirus (HR-HPV) assay compared to a DNA HR-HPV assay in the English cervical screening programme: a decision tree model based economic evaluation
P478volume10

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