From Focal Lipid Storage to Systemic Inflammation: JACC Review Topic of the Week

scientific article published on 01 September 2019

From Focal Lipid Storage to Systemic Inflammation: JACC Review Topic of the Week is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/J.JACC.2019.07.061
P698PubMed publication ID31537270

P2093author name stringPeter Libby
Göran K Hansson
P2860cites workIdentification of splenic reservoir monocytes and their deployment to inflammatory sitesQ24649151
Regulation of an inflammatory disease: Krüppel-like factors and atherosclerosisQ26852339
Biomechanics of vascular mechanosensation and remodelingQ28067208
A century of cholesterol and coronaries: from plaques to genes to statinsQ28080618
Age-related clonal hematopoiesis associated with adverse outcomesQ28386602
Vascular endothelial growth factor is a secreted angiogenic mitogenQ28646475
Inflammation, atherosclerosis, and coronary artery diseaseQ29547232
The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholineQ29547539
Rosuvastatin to prevent vascular events in men and women with elevated C-reactive proteinQ29547752
Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy menQ29619308
Vascular Smooth Muscle Cells in AtherosclerosisQ30277316
Atherosclerosis research from past to present--on the track of two pathologists with opposing views, Carl von Rokitansky and Rudolf VirchowQ33239820
The pathogenesis of atherosclerosis (first of two parts)Q33492794
Atherosclerosis and the arterial smooth muscle cell: Proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosisQ34207431
Classics in arteriosclerosis research: On experimental cholesterin steatosis and its significance in the origin of some pathological processes by N. Anitschkow and S. Chalatow, translated by Mary Z. Pelias, 1913Q70249421
Studies of hypercholesterolemia in the nonhuman primate. I. Changes that lead to fatty streak formationQ70580552
Changes in the endothelium of the aorta and the behaviour of macrophages in experimental atheroma of rabbitsQ78335068
Thrombosis as a factor in the pathogenesis of coronary atherosclerosisQ82176732
Never Waste a Good Crisis: Confronting Reproducibility in Translational ResearchQ88328407
Low-Grade Inflammation in the Association between Mild-to-Moderate Hypertriglyceridemia and Risk of Acute Pancreatitis: A Study of More Than 115000 Individuals from the General PopulationQ90287214
JAK2-V617F promotes venous thrombosis through β1/β2 integrin activationQ90340948
Macrophage Inflammation, Erythrophagocytosis, and Accelerated Atherosclerosis in Jak2 V617F MiceQ90668200
Colchicine in Cardiovascular Disease: Repurposing an Ancient Gout DrugQ90803840
Chemokines as Therapeutic Targets in Cardiovascular DiseaseQ91552719
Sleep modulates haematopoiesis and protects against atherosclerosisQ91560031
Immunotherapy for cardiovascular diseaseQ92241512
Single-Cell Analysis of the Normal Mouse Aorta Reveals Functionally Distinct Endothelial Cell PopulationsQ92410796
Targeting the Immune System in Atherosclerosis: JACC State-of-the-Art ReviewQ92855989
Low-Dose Methotrexate for the Prevention of Atherosclerotic EventsQ92980641
Has the time finally come to measure hsCRP universally in primary and secondary cardiovascular prevention?Q93211515
From studies of biochemical mechanism to novel biological mediators: Prostaglandin endoperoxides, thromboxanes, and leukotriencesQ34255111
Pathophysiology of coronary artery diseaseQ34429470
Factors of risk in the development of coronary heart disease--six year follow-up experience. The Framingham StudyQ34539702
Expression of class II transplantation antigen on vascular smooth muscle cells in human atherosclerosisQ34541589
Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in miceQ34549707
Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease.Q34558126
Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery diseaseQ35062523
Evidence for a Monoclonal Origin of Human Atherosclerotic PlaquesQ35105935
Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesisQ35679591
The role of the monocyte in atherogenesis: I. Transition of blood-borne monocytes into foam cells in fatty lesionsQ35864063
Adaptive Response of T and B Cells in AtherosclerosisQ35928023
Vascular endothelium, hemodynamics, and the pathobiology of atherosclerosisQ36041802
Endothelial Cell Dysfunction and the Pathobiology of AtherosclerosisQ36602763
Leukocytes Link Local and Systemic Inflammation in Ischemic Cardiovascular Disease: An Expanded "Cardiovascular Continuum".Q36654171
Intertwining of thrombosis and inflammation in atherosclerosisQ36667645
Local proliferation dominates lesional macrophage accumulation in atherosclerosisQ37161176
Discovery of the role of wall shear in atherosclerosisQ37336484
Antiinflammatory Therapy with Canakinumab for Atherosclerotic DiseaseQ38606033
Trained immunity: A program of innate immune memory in health and disease.Q38814347
A guiding map for inflammationQ40128384
The pathogenesis of atherosclerosis (second of two parts)Q40547842
Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteriesQ41381379
Endotoxin and tumor necrosis factor induce interleukin-1 gene expression in adult human vascular endothelial cellsQ42752391
Oxidized low-density lipoprotein and atherosclerosisQ43816762
Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth FactorQ45798365
Low-dose colchicine for secondary prevention of cardiovascular diseaseQ46245044
Murine "model" monotheism: an iconoclast at the altar of mouseQ46643118
Interleukin-1 Beta as a Target for Atherosclerosis Therapy: Biological Basis of CANTOS and BeyondQ47599422
NHLBI Working Group Recommendations to Reduce Lipoprotein(a)-Mediated Risk of Cardiovascular Disease and Aortic Stenosis.Q50081201
Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass Cytometry.Q52653300
Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis.Q52653301
Increased neutrophil extracellular trap formation promotes thrombosis in myeloproliferative neoplasms.Q52719979
Inflammation, Immunity, and Infection in Atherothrombosis: JACC Review Topic of the WeekQ57797462
Rationale and design of the Pemafibrate to Reduce Cardiovascular Outcomes by Reducing Triglycerides in Patients with Diabetes (PROMINENT) studyQ57820905
CHIP (Clonal Hematopoiesis of Indeterminate Potential)Q57823938
Natural regulatory T cells control the development of atherosclerosis in miceQ58149268
The Prognostic Value of C-Reactive Protein and Serum Amyloid A Protein in Severe Unstable AnginaQ58230388
Macrophage Trafficking, Inflammatory Resolution, and Genomics in Atherosclerosis: JACC Macrophage in CVD Series (Part 2)Q58592678
Low-dose interleukin-2 in patients with stable ischaemic heart disease and acute coronary syndromes (LILACS): protocol and study rationale for a randomised, double-blind, placebo-controlled, phase I/II clinical trialQ58732372
Low-Density Lipoprotein-Reactive T Cells Regulate Plasma Cholesterol Levels and Development of Atherosclerosis in Humanized Hypercholesterolemic Mice.Q64915291
Thrombin potently stimulates cytokine production in human vascular smooth muscle cells but not in mononuclear phagocytes.Q64997505
Angiogenic factors: regulators of blood supply-side biology. FGF, endothelial cell growth factors and angiogenesis: a keystone symposium, Keystone, CO, USA, April 1-7, 1991Q67702489
Regional accumulations of T cells, macrophages, and smooth muscle cells in the human atherosclerotic plaqueQ69990504
P433issue12
P921main subjectsystemic inflammationQ7663815
P304page(s)1594-1607
P577publication date2019-09-01
P1433published inJournal of the American College of CardiologyQ2984355
P1476titleFrom Focal Lipid Storage to Systemic Inflammation: JACC Review Topic of the Week
P478volume74

Reverse relations

cites work (P2860)
Q92931292ANGPTL3, PCSK9, and statin therapy drive remarkable reductions in hyperlipidemia and atherosclerosis in a mouse model
Q90460683Cholesterol versus Inflammation as Cause of Chronic Diseases
Q112744936Cysteamine Decreases Low-Density Lipoprotein Oxidation, Causes Regression of Atherosclerosis, and Improves Liver and Muscle Function in Low-Density Lipoprotein Receptor-Deficient Mice
Q104134981Mild hyperlipidemia in mice aggravates platelet responsiveness in thrombus formation and exploration of platelet proteome and lipidome