Baloxavir marboxil in Japanese pediatric patients with influenza: safety and clinical and virologic outcomes

scientific article published on 20 September 2019

Baloxavir marboxil in Japanese pediatric patients with influenza: safety and clinical and virologic outcomes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/CID/CIZ908
P932PMC publication ID7428393
P698PubMed publication ID31538644

P50authorFrederick G HaydenQ87843428
P2093author name stringNobuo Hirotsu
Akira Watanabe
Hiroki Sakaguchi
Takeki Uehara
Keiko Baba
Toru Ishibashi
Kenji Tsuchiya
Chisako Sato
Takao Shishido
Shinya Omoto
P2860cites workClinical effectiveness of four neuraminidase inhibitors (oseltamivir, zanamivir, laninamivir, and peramivir) for children with influenza A and B in the 2014-2015 to 2016-2017 influenza seasons in Japan.Q52682568
Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil.Q55426854
Safety, Tolerability, and Pharmacokinetics of the Novel Anti-influenza Agent Baloxavir Marboxil in Healthy Adults: Phase I Study FindingsQ57025849
In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunitQ57474158
Baloxavir Marboxil for Uncomplicated Influenza in Adults and AdolescentsQ59353237
Detection of influenza A(H3N2) viruses exhibiting reduced susceptibility to the novel cap-dependent endonuclease inhibitor baloxavir in Japan, December 2018Q61814195
Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal InfluenzaaQ64134362
COMMITTEE ON INFECTIOUS DISEASES. Recommendations for Prevention and Control of Influenza in Children, 2017 - 2018. Pediatrics. 2017;140(4):e20172550Q89758414
Population Pharmacokinetic and Exposure-Response Analyses of Baloxavir Marboxil in Adults and Adolescents Including Patients With InfluenzaQ90585734
Treatment-Emergent Influenza Variant Viruses With Reduced Baloxavir Susceptibility: Impact on Clinical and Virologic Outcomes in Uncomplicated InfluenzaQ91917768
Influenza A(H3N2) virus exhibiting reduced susceptibility to baloxavir due to a polymerase acidic subunit I38T substitution detected from a hospitalised child without prior baloxavir treatment, Japan, January 2019Q92633011
Population Pharmacokinetics of Baloxavir Marboxil in Japanese Pediatric Influenza PatientsQ93178609
Efficacy, safety, and pharmacokinetics of intravenous peramivir in children with 2009 pandemic H1N1 influenza A virus infectionQ30408582
Prevalence of seropositivity to pandemic influenza A/H1N1 virus in the United States following the 2009 pandemicQ30423135
Influenza virus resistance to neuraminidase inhibitors.Q30428660
Emergence and apparent transmission of rimantadine-resistant influenza A virus in familiesQ30460018
Oral oseltamivir treatment of influenza in children.Q32064242
Long-acting neuraminidase inhibitor laninamivir octanoate (CS-8958) versus oseltamivir as treatment for children with influenza virus infectionQ33876428
Comparison of the clinical effectiveness of zanamivir and laninamivir octanoate for children with influenza A(H3N2) and B in the 2011-2012 seasonQ34292651
Characteristics of a widespread community cluster of H275Y oseltamivir-resistant A(H1N1)pdm09 influenza in Australia.Q36048315
Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysisQ37955413
Early oseltamivir treatment of influenza in children 1-3 years of age: a randomized controlled trialQ38500366
Influenza Vaccine Effectiveness in the United States during the 2015-2016 SeasonQ40089214
Efficacy of oseltamivir treatment started within 5 days of symptom onset to reduce influenza illness duration and virus shedding in an urban setting in Bangladesh: a randomised placebo-controlled trialQ40152886
Comparison of the clinical effectiveness of oseltamivir and zanamivir against influenza virus infection in childrenQ40415936
The course of fever following influenza virus infection in children treated with oseltamivirQ40421191
Effectiveness of oseltamivir treatment among children with influenza A or B virus infections during four successive winters in Niigata City, Japan.Q40426705
Lower clinical effectiveness of oseltamivir against influenza B contrasted with influenza A infection in children.Q40462169
A community cluster of influenza A(H1N1)pdm09 virus exhibiting cross-resistance to oseltamivir and peramivir in Japan, November to December 2013.Q42232612
Influenza-associated pediatric deaths in the United States, 2004-2012.Q42259236
P275copyright licenseCreative Commons Attribution-NonCommercial-NoDerivs 4.0 InternationalQ24082749
P6216copyright statuscopyrightedQ50423863
P577publication date2019-09-20
P1433published inClinical Infectious DiseasesQ5133764
P1476titleBaloxavir marboxil in Japanese pediatric patients with influenza: safety and clinical and virologic outcomes

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cites work (P2860)
Q89877245Favipiravir, an anti-influenza drug against life-threatening RNA virus infections
Q90689822Influenza A and B viruses with reduced baloxavir susceptibility display attenuated in vitro fitness but retain ferret transmissibility
Q96126746Modeling mitigation of influenza epidemics by baloxavir
Q89843860Next-generation direct-acting influenza therapeutics
Q89739869Rapid detection of an I38T amino acid substitution in influenza polymerase acidic subunit associated with reduced susceptibility to baloxavir marboxil
Q94570381Very high sensitivity of a rapid influenza diagnostic test in adults and elderly individuals within 48 hours of the onset of illness

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