CCL2 secreted from cancer-associated mesothelial cells promotes peritoneal metastasis of ovarian cancer cells through the P38-MAPK pathway

scientific article published on 21 September 2019

CCL2 secreted from cancer-associated mesothelial cells promotes peritoneal metastasis of ovarian cancer cells through the P38-MAPK pathway is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S10585-019-09993-Y
P698PubMed publication ID31541326

P50authorFumitaka KikkawaQ89568553
P2093author name stringYang Peng
Hiroaki Kajiyama
Kae Nakamura
Shiro Suzuki
Nobuhisa Yoshikawa
Satoshi Tamauchi
Hiroaki Yasui
Mai Sugiyama
P2860cites workThe chemokine monocyte chemotactic protein 1 triggers Janus kinase 2 activation and tyrosine phosphorylation of the CCR2B receptorQ24316405
The preclinical natural history of serous ovarian cancer: defining the target for early detectionQ33487678
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Possible involvement of SDF-1alpha/CXCR4-DPPIV axis in TGF-beta1-induced enhancement of migratory potential in human peritoneal mesothelial cellsQ81230145
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The chemokine (CCL2-CCR2) signaling axis mediates perineural invasionQ35108960
Multidetector CT of Peritoneal Carcinomatosis from Ovarian CancerQ35124938
The chemokine, CXCL12, is an independent predictor of poor survival in ovarian cancerQ35858991
CCL2 Mediates Cross-talk between Cancer Cells and Stromal Fibroblasts That Regulates Breast Cancer Stem CellsQ36007881
CCL2/CCR2 Chemokine Signaling Coordinates Survival and Motility of Breast Cancer Cells through Smad3 Protein- and p42/44 Mitogen-activated Protein Kinase (MAPK)-dependent MechanismsQ36332973
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Monocyte chemoattractant protein-1 serum levels in ovarian cancer patientsQ36640987
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Impact of the putative cancer stem cell markers and growth factor receptor expression on the sensitivity of ovarian cancer cells to treatment with various forms of small molecule tyrosine kinase inhibitors and cytotoxic drugs.Q37337898
Blockade of MCP-1/CCR4 signaling-induced recruitment of activated regulatory cells evokes an antitumor immune response in head and neck squamous cell carcinomaQ37437275
7-(O)-Carboxymethyl daidzein conjugated to N-t-Boc-hexylenediamine: a novel compound capable of inducing cell death in epithelial ovarian cancer stem cellsQ37441283
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Cancer-associated fibroblasts induce epithelial-mesenchymal transition of breast cancer cells through paracrine TGF-β signallingQ37559049
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Cancer-associated fibroblasts promote hepatocellular carcinoma metastasis through chemokine-activated hedgehog and TGF-β pathwaysQ38769001
CCL2 promotes integrin-mediated adhesion of prostate cancer cells in vitroQ38960744
MCP-1 promotes invasion and adhesion of human ovarian cancer cellsQ39063837
CCL2 increases αvβ3 integrin expression and subsequently promotes prostate cancer migrationQ39127265
The Unique Molecular and Cellular Microenvironment of Ovarian CancerQ39169603
Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathwayQ39315794
CCL2 expression in primary ovarian carcinoma is correlated with chemotherapy response and survival outcomesQ39615263
Reciprocal activation of prostate cancer cells and cancer-associated fibroblasts stimulates epithelial-mesenchymal transition and cancer stemnessQ39668916
CCL2 at the crossroad of cancer metastasisQ42136303
Global Cancer in Women: Burden and TrendsQ44404178
Serum levels of IL-6, IL-8 and CRP as prognostic factors in epithelial ovarian cancer.Q45283850
Expression of the miR200 family of microRNAs in mesothelial cells suppresses the dissemination of ovarian cancer cellsQ46538151
CCL2/CCR2 axis induces hepatocellular carcinoma invasion and epithelial-mesenchymal transition in vitro through activation of the Hedgehog pathwayQ49187592
A novel mechanism of neovascularization in peritoneal dissemination via cancer-associated mesothelial cells affected by TGF-β derived from ovarian cancerQ49384884
CCL2/CCL5 secreted by the stroma induce IL-6/PYK2 dependent chemoresistance in ovarian cancerQ49888066
Screening for Ovarian Cancer: US Preventive Services Task Force Recommendation StatementQ49951147
P433issue1
P921main subjectovarian cancerQ172341
P304page(s)145-158
P577publication date2019-09-21
P1433published inClinical & Experimental MetastasisQ13470030
P1476titleCCL2 secreted from cancer-associated mesothelial cells promotes peritoneal metastasis of ovarian cancer cells through the P38-MAPK pathway
P478volume37

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Q93001507Chemokines and their Receptors: Multifaceted Roles in Cancer Progression and Potential Value as Cancer Prognostic Markerscites workP2860

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