Incorporating new approach methodologies in toxicity testing and exposure assessment for tiered risk assessment using the RISK21 approach: Case studies on food contact chemicals

scientific article published on 20 September 2019

Incorporating new approach methodologies in toxicity testing and exposure assessment for tiered risk assessment using the RISK21 approach: Case studies on food contact chemicals is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.FCT.2019.110819
P698PubMed publication ID31545997

P50authorAgnes L. KarmausQ39831384
Barbara A WetmoreQ63350819
P2093author name stringMansi Krishan
Kristin K Isaacs
Michelle R Embry
Alexandra E Turley
P2860cites workToxCast Chemical Landscape: Paving the Road to 21st Century ToxicologyQ28025527
Data gaps in toxicity testing of chemicals allowed in food in the United StatesQ30662042
Using ToxCast™ Data to Reconstruct Dynamic Cell State Trajectories and Estimate Toxicological Points of DepartureQ31006619
Scaling factors for the extrapolation of in vivo metabolic drug clearance from in vitro data: reaching a consensus on values of human microsomal protein and hepatocellularity per gram of liver.Q31096663
tcpl: the ToxCast pipeline for high-throughput screening dataQ31140137
The toxicity data landscape for environmental chemicalsQ33455654
Endocrine profiling and prioritization of environmental chemicals using ToxCast dataQ33687961
In vitro screening of environmental chemicals for targeted testing prioritization: the ToxCast projectQ33789756
Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessmentQ34031014
The ToxCast program for prioritizing toxicity testing of environmental chemicalsQ34564990
Test driving ToxCast: endocrine profiling for 1858 chemicals included in phase II.Q34979500
Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity TestingQ36204768
Using in vitro high throughput screening assays to identify potential endocrine-disrupting chemicals.Q36537278
Improving the human hazard characterization of chemicals: a Tox21 updateQ36984065
On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens.Q37158812
Quantitative in vitro-to-in vivo extrapolation in a high-throughput environmentQ38218404
A 21st century roadmap for human health risk assessmentQ38234791
Risk assessment in the 21st century: roadmap and matrix.Q38234793
Pyrithione, a zinc ionophore, inhibits NF-kappaB activationQ38527829
High-throughput dietary exposure predictions for chemical migrants from food contact substances for use in chemical prioritizationQ38596889
Predicting organ toxicity using in vitro bioactivity data and chemical structureQ38646520
Curation of food-relevant chemicals in ToxCast.Q38912534
High throughput heuristics for prioritizing human exposure to environmental chemicalsQ39108369
Bioorganotin chemistry. Metabolism of organotin compounds in microsomal monooxygenase systems and in mammalsQ39127299
Effect of taurine on acinar cell apoptosis and pancreatic fibrosis in dibutyltin dichloride-induced chronic pancreatitisQ39291949
Informing the Human Plasma Protein Binding of Environmental Chemicals by Machine Learning in the Pharmaceutical Space: Applicability Domain and Limits of PredictabilityQ39340009
Relative impact of incorporating pharmacokinetics on predicting in vivo hazard and mode of action from high-throughput in vitro toxicity assaysQ39477437
Update on EPA's ToxCast program: providing high throughput decision support tools for chemical risk management.Q39626913
Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.Q39747696
Evaluation of food-relevant chemicals in the ToxCast high-throughput screening programQ39831317
Using ToxCast to Explore Chemical Activities and Hazard Traits: A Case Study With Ortho-PhthalatesQ39927114
MIGRESIVES: a research project on migration from adhesives in food-packaging materials in support of European legislation and standardization.Q39927604
Requirement of caspase and p38MAPK activation in zinc-induced apoptosis in human leukemia HL-60 cellsQ40684583
A Comparison of ToxCast Test Results with In Vivo and Other In Vitro Endpoints for Neuro, Endocrine, and Developmental Toxicities: A Case Study Using Endosulfan and MethidathionQ40897316
Metabolic disposition of pyrithionesQ42253484
Pyrithione and 8-hydroxyquinolines transport lead across erythrocyte membranesQ43295718
Assessment of di- and tri-butyltin interaction with skeletal muscle membranesQ43744170
Activation of a calcium entry pathway by sodium pyrithione in the bag cell neurons of AplysiaQ45015561
SHEDS-HT: an integrated probabilistic exposure model for prioritizing exposures to chemicals with near-field and dietary sourcesQ46206576
Changes in liver volume from birth to adulthood: a meta-analysis.Q51959232
Consensus Modeling of Median Chemical Intake for the U.S. Population Based on Predictions of Exposure PathwaysQ60367109
Comparison of hepatotoxicity caused by mono-, di- and tributyltin compounds in miceQ72158184
Speciation of organotins in poly(vinyl chloride) productsQ72565609
Physiological parameters in laboratory animals and humansQ72935917
P921main subjectexposure assessmentQ4008388
P304page(s)110819
P577publication date2019-09-20
P1433published inFood and Chemical ToxicologyQ776926
P1476titleIncorporating new approach methodologies in toxicity testing and exposure assessment for tiered risk assessment using the RISK21 approach: Case studies on food contact chemicals
P478volume134

Reverse relations

Q99413500Evaluating consumer exposure to disinfecting chemicals against coronavirus disease 2019 (COVID-19) and associated health riskscites workP2860

Search more.