scholarly article | Q13442814 |
P50 | author | Jeffrey A Bluestone | Q87186905 |
P2093 | author name string | Arabella Young | |
Zoe Quandt | |||
P2860 | cites work | The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice | Q24670319 |
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor | Q28144319 | ||
Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice | Q28201627 | ||
Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4 | Q28284177 | ||
Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4 | Q29619280 | ||
Safety profiles of anti-CTLA-4 and anti-PD-1 antibodies alone and in combination | Q30251438 | ||
Vedolizumab treatment for immune checkpoint inhibitor-induced enterocolitis | Q33607108 | ||
Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors | Q33707098 | ||
Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape | Q34241893 | ||
PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice | Q34577678 | ||
Blockade of the programmed death-1 (PD1) pathway undermines potent genetic protection from type 1 diabetes | Q35107621 | ||
Immune-checkpoint proteins VISTA and PD-1 nonredundantly regulate murine T-cell responses. | Q35669414 | ||
Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota | Q35833921 | ||
Intestinal microbiome analyses identify melanoma patients at risk for checkpoint-blockade-induced colitis | Q35912366 | ||
Inflammatory arthritis and sicca syndrome induced by nivolumab and ipilimumab. | Q50626424 | ||
β Cells that Resist Immunological Attack Develop during Progression of Autoimmune Diabetes in NOD Mice. | Q50897119 | ||
Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity. | Q50974735 | ||
Baseline antibody profiles predict toxicity in melanoma patients treated with immune checkpoint inhibitors. | Q52615452 | ||
Autoantibodies May Predict Immune-Related Toxicity: Results from a Phase I Study of Intralesional Bacillus Calmette-Guérin followed by Ipilimumab in Patients with Advanced Metastatic Melanoma. | Q52649833 | ||
Negative association of antibiotics on clinical activity of immune checkpoint inhibitors in patients with advanced renal cell and non-small cell lung cancer. | Q52721675 | ||
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes. | Q52729451 | ||
Immune-checkpoint inhibitor-induced diarrhea and colitis in patients with advanced malignancies: retrospective review at MD Anderson. | Q54215187 | ||
Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies. | Q55421471 | ||
Deficiency of host CD96 and PD-1 or TIGIT enhances tumor immunity without significantly compromising immune homeostasis | Q56892731 | ||
Bispecific antibodies in cancer immunotherapy | Q56893015 | ||
Pituitary expression of CTLA-4 mediates hypophysitis secondary to administration of CTLA-4 blocking antibody | Q56896949 | ||
Targeting EZH2 Reprograms Intratumoral Regulatory T Cells to Enhance Cancer Immunity | Q57160066 | ||
Infliximab for IPILIMUMAB-Related Colitis--Letter | Q58025377 | ||
CAR T cell-induced cytokine release syndrome is mediated by macrophages and abated by IL-1 blockade. | Q64950601 | ||
Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells | Q88885438 | ||
Collateral Damage: Insulin-Dependent Diabetes Induced With Checkpoint Inhibitors | Q89224295 | ||
High-dose glucocorticoids for the treatment of ipilimumab-induced hypophysitis is associated with reduced survival in patients with melanoma | Q89429146 | ||
Baseline circulating IL-17 predicts toxicity while TGF-β1 and IL-10 are prognostic of relapse in ipilimumab neoadjuvant therapy of melanoma | Q36061606 | ||
The NOD mouse: a model of immune dysregulation | Q36072434 | ||
Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway. | Q36228158 | ||
Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes | Q36400199 | ||
Gene expression profiling of whole blood in ipilimumab-treated patients for identification of potential biomarkers of immune-related gastrointestinal adverse events | Q36798441 | ||
Clonal expansion of CD8 T cells in the systemic circulation precedes development of ipilimumab-induced toxicities | Q37369239 | ||
Immune-Related Adverse Events, Need for Systemic Immunosuppression, and Effects on Survival and Time to Treatment Failure in Patients With Melanoma Treated With Ipilimumab at Memorial Sloan Kettering Cancer Center | Q37380454 | ||
Anti-CTLA-4 antibody therapy associated autoimmune hypophysitis: serious immune related adverse events across a spectrum of cancer subtypes | Q37565259 | ||
Fulminant Myocarditis with Combination Immune Checkpoint Blockade | Q37595462 | ||
Clinical applications of diabetes antibody testing | Q37624232 | ||
Vitiligo-like depigmentation in patients with stage III-IV melanoma receiving immunotherapy and its association with survival: a systematic review and meta-analysis | Q38326290 | ||
Boosting Cancer Immunotherapy with Anti-CD137 Antibody Therapy. | Q38440279 | ||
Is autoimmunity the Achilles' heel of cancer immunotherapy? | Q38687375 | ||
Assessing Immune-Related Adverse Events of Efficacious Combination Immunotherapies in Preclinical Models of Cancer. | Q38752932 | ||
Suppression of Metastases Using a New Lymphocyte Checkpoint Target for Cancer Immunotherapy | Q38801519 | ||
Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation. | Q38837469 | ||
The future of cancer treatment: immunomodulation, CARs and combination immunotherapy | Q38875355 | ||
Treatment of the Immune-Related Adverse Effects of Immune Checkpoint Inhibitors: A Review. | Q38883332 | ||
Rescue of exhausted CD8 T cells by PD-1-targeted therapies is CD28-dependent. | Q38916367 | ||
Safety Profile of Nivolumab Monotherapy: A Pooled Analysis of Patients With Advanced Melanoma | Q39031722 | ||
Autoimmune diabetes induced by PD-1 inhibitor-retrospective analysis and pathogenesis: a case report and literature review | Q39387413 | ||
Baseline gut microbiota predicts clinical response and colitis in metastatic melanoma patients treated with ipilimumab | Q40262479 | ||
Antibody-mediated thyroid dysfunction during T-cell checkpoint blockade in patients with non-small-cell lung cancer | Q40414975 | ||
Pneumonitis in Patients Treated With Anti-Programmed Death-1/Programmed Death Ligand 1 Therapy. | Q40534742 | ||
HLA Markers DQ8 and DR53 Are Associated With Lymphocytic Hypophysitis and May Aid in Differential Diagnosis | Q40596434 | ||
Selective inhibition of autoimmune exacerbation while preserving the anti-tumor clinical benefit using IL-6 blockade in a patient with advanced melanoma and Crohn's disease: a case report | Q41018488 | ||
Anti-CTLA-4 antibodies of IgG2a isotype enhance antitumor activity through reduction of intratumoral regulatory T cells | Q43448621 | ||
T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition. | Q44384732 | ||
Hypophysitis Secondary to Cytotoxic T-Lymphocyte-Associated Protein 4 Blockade: Insights into Pathogenesis from an Autopsy Series | Q45839919 | ||
Immune Toxicities Elicted by CTLA-4 Blockade in Cancer Patients Are Associated with Early Diversification of the T-cell Repertoire | Q46177852 | ||
Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group | Q47102520 | ||
Association of Immune-Related Adverse Events With Nivolumab Efficacy in Non-Small-Cell Lung Cancer | Q47252798 | ||
Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients. | Q47447695 | ||
Chimeric antigen receptor T-cell therapy - assessment and management of toxicities. | Q47681829 | ||
Successful treatment of arthritis induced by checkpoint inhibitors with tocilizumab: a case series. | Q47919775 | ||
Interleukin-6 as one of the potential mediators of immune-related adverse events in non-small cell lung cancer patients treated with immune checkpoint blockade: evidence from a case report. | Q48241683 | ||
The commensal microbiome is associated with anti-PD-1 efficacy in metastatic melanoma patients. | Q48306869 | ||
Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors | Q48373246 | ||
Immune checkpoint blockade combined with IL-6 and TGF-β inhibition improves the therapeutic outcome of mRNA-based immunotherapy. | Q49720370 | ||
Uncoupling therapeutic from immunotherapy-related adverse effects for safer and effective anti-CTLA-4 antibodies in CTLA4 humanized mice. | Q49788993 | ||
Early B cell changes predict autoimmunity following combination immune checkpoint blockade | Q50140526 | ||
P433 | issue | 12 | |
P921 | main subject | immunotherapy | Q1427096 |
P304 | page(s) | 1445-1452 | |
P577 | publication date | 2018-12-01 | |
P1433 | published in | Cancer Immunology Research | Q26841983 |
P1476 | title | The Balancing Act between Cancer Immunity and Autoimmunity in Response to Immunotherapy | |
P478 | volume | 6 |
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