| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Sundas Arshad | Q90292394 |
| P2093 | author name string | Muhammad Naveed | |
| Khadija Javed | |||
| Ayesha Butt | |||
| Fazeeha Amjad | |||
| Mahad Ullia | |||
| Masooma Khawar | |||
| P2860 | cites work | Systemic lipopolysaccharide and interleukin-1beta activate the interleukin 6: STAT intracellular signaling pathway in neurons of mouse trigeminal ganglion | Q73473107 |
| Inhibition of pp60c-Src reduces Bcl-XL expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors | Q78192920 | ||
| Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis | Q78836958 | ||
| Expression of p-STAT3 in human gastric carcinoma: significant correlation in tumour invasion and prognosis | Q79488473 | ||
| Inhibition of normal lymphocyte proliferation by Indirubin-3'-monoxime: a multifactorial process | Q80206113 | ||
| An oxazole-based small-molecule Stat3 inhibitor modulates Stat3 stability and processing and induces antitumor cell effects | Q80394633 | ||
| Rationally designed inhibitors identify STAT3 N-domain as a promising anticancer drug target | Q80394637 | ||
| SOCS3 negatively regulates the gp130-STAT3 pathway in mouse skin wound healing | Q80471865 | ||
| Validating Stat3 in cancer therapy | Q81816295 | ||
| Targeting STAT3 in cancer: how successful are we? | Q82824786 | ||
| E-cadherin and, in its absence, N-cadherin promotes Nanog expression in mouse embryonic stem cells via STAT3 phosphorylation | Q84373219 | ||
| IL-6 Mediates Cross-Talk between Tumor Cells and Activated Fibroblasts in the Tumor Microenvironment | Q89433406 | ||
| CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling | Q24290848 | ||
| Cutting edge: A transcriptional repressor and corepressor induced by the STAT3-regulated anti-inflammatory signaling pathway | Q24300905 | ||
| Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway | Q24305237 | ||
| A family of cytokine-inducible inhibitors of signalling | Q24313168 | ||
| Molecular cloning and expression of an IL-6 signal transducer, gp130 | Q24328945 | ||
| Principles of interleukin (IL)-6-type cytokine signalling and its regulation | Q24530173 | ||
| Activation and association of Stat3 with Src in v-Src-transformed cell lines | Q24650319 | ||
| The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation | Q24654107 | ||
| Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas | Q24669579 | ||
| Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality | Q24685515 | ||
| Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells | Q24802990 | ||
| Three-dimensional structure of the Stat3beta homodimer bound to DNA | Q27764842 | ||
| Drug discovery: a historical perspective | Q28138834 | ||
| Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress | Q28142513 | ||
| Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR | Q28144113 | ||
| Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors | Q28235378 | ||
| Interleukin-6 promotes cervical tumor growth by VEGF-dependent angiogenesis via a STAT3 pathway | Q61623437 | ||
| STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice. | Q36570495 | ||
| Downstream signalling and specific inhibition of c-MET/HGF pathway in small cell lung cancer: implications for tumour invasion | Q36610910 | ||
| A novel inhibitor of the STAT3 pathway induces apoptosis in malignant glioma cells both in vitro and in vivo | Q36647747 | ||
| Twist is transcriptionally induced by activation of STAT3 and mediates STAT3 oncogenic function | Q36662693 | ||
| STAT3 as a central mediator of neoplastic cellular transformation | Q36665485 | ||
| Constitutive activation of STAT3 in breast cancer cells: A review | Q36711689 | ||
| The JAK-STAT signaling pathway: input and output integration | Q36740971 | ||
| Generation of plasmacytomas with the chromosomal translocation t(12;15) in interleukin 6 transgenic mice. | Q36765782 | ||
| SOCS proteins, cytokine signalling and immune regulation | Q36831668 | ||
| First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy. | Q36890491 | ||
| STAT-mediated EGFR signaling in cancer. | Q36895477 | ||
| Targeting the cytoplasmic and nuclear functions of signal transducers and activators of transcription 3 for cancer therapy | Q36957261 | ||
| A genetic and developmental pathway from STAT3 to the OCT4-NANOG circuit is essential for maintenance of ICM lineages in vivo. | Q36981774 | ||
| Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours | Q37224637 | ||
| Shc mediates IL-6 signaling by interacting with gp130 and Jak2 kinase | Q28236581 | ||
| STAT3 nuclear import is independent of tyrosine phosphorylation and mediated by importin-alpha3. | Q28253106 | ||
| Specific inhibition of Stat3 signal transduction by PIAS3 | Q28255665 | ||
| Induction of epithelial tubules by growth factor HGF depends on the STAT pathway | Q28259695 | ||
| Stat3 is a negative regulator of intestinal tumor progression in Apc(Min) mice | Q28266642 | ||
| Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders | Q28272795 | ||
| Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor | Q28291157 | ||
| STAT3 as a therapeutic target in head and neck cancer | Q28299368 | ||
| Cytoprotection by the modulation of mitochondrial electron transport chain: the emerging role of mitochondrial STAT3 | Q28396645 | ||
| STAT3 negatively regulates thyroid tumorigenesis | Q28505424 | ||
| Fetal liver development requires a paracrine action of oncostatin M through the gp130 signal transducer | Q28508942 | ||
| Cyclin-dependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity | Q28512261 | ||
| Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6 | Q28637521 | ||
| Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression | Q28638072 | ||
| Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins | Q28645718 | ||
| The STATs of cancer--new molecular targets come of age | Q29614601 | ||
| Stat3 as an oncogene | Q29614606 | ||
| Molecular disruption of oncogenic signal transducer and activator of transcription 3 (STAT3) protein | Q30911799 | ||
| Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity | Q33282964 | ||
| Inhibition of Stat3 activation and tumor growth suppression of non-small cell lung cancer by G-quartet oligonucleotides. | Q33286711 | ||
| Therapeutic effects of STAT3 decoy oligodeoxynucleotide on human lung cancer in xenograft mice | Q33293430 | ||
| Phase 2 study of CEP-701, an orally available JAK2 inhibitor, in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis | Q33387514 | ||
| Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis | Q33391880 | ||
| JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis | Q33399977 | ||
| IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway | Q33591332 | ||
| STAT inhibitors for cancer therapy. | Q33644206 | ||
| Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells | Q33770989 | ||
| Stat3 activation is required for cellular transformation by v-src | Q33786469 | ||
| Mechanism-based target identification and drug discovery in cancer research | Q33864633 | ||
| Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice | Q34185116 | ||
| IgG1 plasmacytosis in interleukin 6 transgenic mice | Q34308376 | ||
| Regulation of dendritic cell differentiation and antitumor immune response in cancer by pharmacologic-selective inhibition of the janus-activated kinase 2/signal transducers and activators of transcription 3 pathway | Q34314210 | ||
| Negative regulation of cytokine signaling. | Q34350006 | ||
| Stat3 dimerization regulated by reversible acetylation of a single lysine residue | Q34384817 | ||
| The JAK kinases: not just another kinase drug discovery target | Q37250023 | ||
| Cutting edge: inherent and acquired resistance to radiation-induced apoptosis in B cells: a pivotal role for STAT3. | Q37406213 | ||
| Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis | Q37486563 | ||
| AZD9150, a next-generation antisense oligonucleotide inhibitor of STAT3 with early evidence of clinical activity in lymphoma and lung cancer | Q37613445 | ||
| Terpenoids: natural products for cancer therapy | Q38054798 | ||
| STAT3 inhibitors: finding a home in lymphoma and leukemia | Q38202556 | ||
| Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis | Q38290076 | ||
| Inhibition of growth and metastasis of human hepatocellular carcinoma by antisense oligonucleotide targeting signal transducer and activator of transcription 3. | Q38307015 | ||
| Targeting signal transducer and activator of transcription 3 with G-quartet oligonucleotides: a potential novel therapy for head and neck cancer | Q38315429 | ||
| Transcriptional activation of the p21(WAF1,CIP1,SDI1) gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effects on human osteoblastic cells | Q38334647 | ||
| The competitive binding of STAT3 and NF-kappaB on an overlapping DNA binding site | Q38343543 | ||
| SOCS3 regulates the plasticity of gp130 signaling | Q38354507 | ||
| SOCS3 negatively regulates IL-6 signaling in vivo | Q38354512 | ||
| Opposite regulation of myc and p21waf1 transcription by STAT3 proteins | Q38360847 | ||
| STAT3 the oncogene - still eluding therapy? | Q38396909 | ||
| Phase I and biomarker study of OPB-51602, a novel signal transducer and activator of transcription (STAT) 3 inhibitor, in patients with refractory solid malignancies. | Q38417469 | ||
| The role of JAK/STAT signalling in the pathogenesis, prognosis and treatment of solid tumours. | Q38543552 | ||
| Targeting transcription factor STAT3 for cancer prevention and therapy. | Q38610564 | ||
| Do STAT3 inhibitors have potential in the future for cancer therapy? | Q38656557 | ||
| A small molecule compound targeting STAT3 DNA-binding domain inhibits cancer cell proliferation, migration, and invasion. | Q39012525 | ||
| Pharmacologic suppression of JAK1/2 by JAK1/2 inhibitor AZD1480 potently inhibits IL-6-induced experimental prostate cancer metastases formation | Q39020147 | ||
| Effect of AZD1480 in an epidermal growth factor receptor-driven lung cancer model | Q39062774 | ||
| Constitutively Activated Jak-STAT Pathway in T Cells Transformed with HTLV-I | Q39250459 | ||
| Regulation of Stat3 nuclear export | Q39741143 | ||
| Sustained Src inhibition results in signal transducer and activator of transcription 3 (STAT3) activation and cancer cell survival via altered Janus-activated kinase-STAT3 binding | Q39882795 | ||
| Guggulsterone, a farnesoid X receptor antagonist, inhibits constitutive and inducible STAT3 activation through induction of a protein tyrosine phosphatase SHP-1. | Q39976217 | ||
| Inhibition of STAT3 Tyr705 phosphorylation by Smad4 suppresses transforming growth factor beta-mediated invasion and metastasis in pancreatic cancer cells | Q39976273 | ||
| JSI-124 inhibits glioblastoma multiforme cell proliferation through G(2)/M cell cycle arrest and apoptosis augment | Q39980916 | ||
| Combined antitumor activity of cucurbitacin B and docetaxel in laryngeal cancer | Q39987494 | ||
| Galiellalactone is a novel therapeutic candidate against hormone-refractory prostate cancer expressing activated Stat3. | Q40029827 | ||
| Protein kinase Cepsilon interacts with signal transducers and activators of transcription 3 (Stat3), phosphorylates Stat3Ser727, and regulates its constitutive activation in prostate cancer | Q40079462 | ||
| Antiproliferative mechanisms of a transcription factor decoy targeting signal transducer and activator of transcription (STAT) 3: the role of STAT1. | Q40166211 | ||
| Ras/ERK1/2-mediated STAT3 Ser727 phosphorylation by familial medullary thyroid carcinoma-associated RET mutants induces full activation of STAT3 and is required for c-fos promoter activation, cell mitogenicity, and transformation. | Q40185668 | ||
| Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 protein | Q40302630 | ||
| Cyclooxygenase-2-dependent activation of signal transducer and activator of transcription 3 by interleukin-6 in non-small cell lung cancer | Q40353025 | ||
| TMF/ARA160 is a BC-box-containing protein that mediates the degradation of Stat3. | Q40507432 | ||
| STAT3 is constitutively activated and supports cell survival in association with survivin expression in gastric cancer cells. | Q40568079 | ||
| Novel peptidomimetic inhibitors of signal transducer and activator of transcription 3 dimerization and biological activity. | Q40577570 | ||
| Curcumin (Diferuloylmethane) Inhibits Constitutive and IL-6-Inducible STAT3 Phosphorylation in Human Multiple Myeloma Cells | Q40633129 | ||
| Leukemia inhibitory factor and interleukin-6 trigger the same immediate early response, including tyrosine phosphorylation, upon induction of myeloid leukemia differentiation | Q40640213 | ||
| Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells | Q40694264 | ||
| Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice | Q40705435 | ||
| Constitutive activation of signal transducers and activators of transcription 3 correlates with cyclin D1 overexpression and may provide a novel prognostic marker in head and neck squamous cell carcinoma. | Q40724591 | ||
| A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6. | Q40806236 | ||
| Induction of apoptosis by extracellular ubiquitin in human hematopoietic cells: possible involvement of STAT3 degradation by proteasome pathway in interleukin 6-dependent hematopoietic cells | Q40831765 | ||
| A stat-responsive element in the promoter of the episialin/MUC1 gene is involved in its overexpression in carcinoma cells | Q40841614 | ||
| Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis. | Q40907792 | ||
| Protein kinase C delta associates with and phosphorylates Stat3 in an interleukin-6-dependent manner | Q40935737 | ||
| Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells | Q40972355 | ||
| STAT3 mediates the survival signal in oncogenic ras-transfected intestinal epithelial cells | Q41003470 | ||
| Gp130-mediated signal transduction in embryonic stem cells involves activation of Jak and Ras/mitogen-activated protein kinase pathways | Q41150318 | ||
| Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein | Q41326706 | ||
| Interleukin 6 influences germinal center development and antibody production via a contribution of C3 complement component | Q41839042 | ||
| Overexpression of phosphorylated-STAT3 correlated with the invasion and metastasis of cutaneous squamous cell carcinoma | Q42481702 | ||
| Improving Response Rates to EGFR-Targeted Therapies for Head and Neck Squamous Cell Carcinoma: Candidate Predictive Biomarkers and Combination Treatment with Src Inhibitors | Q42545098 | ||
| Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis | Q42679964 | ||
| STAT3 is required for the gp130-mediated full activation of the c-myc gene | Q42753357 | ||
| Ratjadones inhibit nuclear export by blocking CRM1/exportin 1. | Q42801742 | ||
| Design of peptide inhibitors for the importin alpha/beta nuclear import pathway by activity-based profiling | Q42808317 | ||
| Nucleocytoplasmic shuttling of persistently activated STAT3. | Q42825173 | ||
| Constitutive activation of Stat3 in fibroblasts transformed by diverse oncoproteins and in breast carcinoma cells. | Q42833476 | ||
| Interleukin-11 up-regulates survivin expression in endothelial cells through a signal transducer and activator of transcription-3 pathway | Q43580516 | ||
| In vivo activation of JAK2/STAT-3 pathway during angiogenesis induced by GM-CSF. | Q43823807 | ||
| Regulation of cell proliferation, apoptosis, and transcription factor activities during the promotion of liver carcinogenesis by polychlorinated biphenyls. | Q43924957 | ||
| Receptor-mediated tobacco toxicity: cooperation of the Ras/Raf-1/MEK1/ERK and JAK-2/STAT-3 pathways downstream of alpha7 nicotinic receptor in oral keratinocytes | Q43942051 | ||
| Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. | Q44021327 | ||
| Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes | Q44021545 | ||
| PTEN is a negative regulator of STAT3 activation in human papillomavirus-infected cells | Q44035401 | ||
| Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma | Q44189596 | ||
| Nuclear factor-kappaB and STAT3 are constitutively active in CD138+ cells derived from multiple myeloma patients, and suppression of these transcription factors leads to apoptosis | Q44834826 | ||
| The role of interleukin-6 in mucosal IgA antibody responses in vivo | Q45872747 | ||
| Cell biology. Moonlighting in mitochondria | Q46131529 | ||
| IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages | Q46376203 | ||
| Ultraviolet B exposure activates Stat3 signaling via phosphorylation at tyrosine705 in skin of SKH1 hairless mouse: a target for the management of skin cancer? | Q46528687 | ||
| Indirubin-3'-monoxime, a derivative of a Chinese anti-leukemia medicine, inhibits Notch1 signaling | Q46699787 | ||
| Regulation of Stat3 nuclear import by importin alpha5 and importin alpha7 via two different functional sequence elements | Q46812595 | ||
| WP1066 disrupts Janus kinase-2 and induces caspase-dependent apoptosis in acute myelogenous leukemia cells | Q46868533 | ||
| Reduced IL-6 levels and tumor-associated phospho-STAT3 are associated with reduced tumor development in a mouse model of lung cancer chemoprevention with myo-inositol | Q47565249 | ||
| Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis | Q47677996 | ||
| Signaling mechanisms through gp130: a model of the cytokine system | Q47992455 | ||
| Activation of stat3 in human melanoma promotes brain metastasis | Q48616814 | ||
| STAT3/PIAS3 levels serve as "early signature" genes in the development of high-grade serous carcinoma from the fallopian tube | Q50020012 | ||
| Construction of Vectors Expressing Inhibiting Peptides for Nuclear Import and Its Effect on Growth and Migration of HeLa Cell | Q50168977 | ||
| Requirement of STAT3 activation for maximal collagenase-1 (MMP-1) induction by epidermal growth factor and malignant characteristics in T24 bladder cancer cells | Q50335893 | ||
| Cooperation between STAT3 and c-jun suppresses Fas transcription. | Q50335898 | ||
| Activation of the interleukin-6/STAT3 antiapoptotic pathway in esophageal cells by bile acids and low pH: relevance to barrett's esophagus | Q50665061 | ||
| Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells. | Q50711998 | ||
| STAT3 regulates NF-kappaB recruitment to the IL-12p40 promoter in dendritic cells | Q50799062 | ||
| Small-molecule inhibitors targeting the DNA-binding domain of STAT3 suppress tumor growth, metastasis and STAT3 target gene expression in vivo | Q50963721 | ||
| Leptomycin B alters the subcellular distribution of CRM1 (Exportin 1). | Q51056428 | ||
| Impaired immune and acute-phase responses in interleukin-6-deficient mice. | Q52514391 | ||
| Disruption of the CNTF gene results in motor neuron degeneration. | Q52516638 | ||
| Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice. | Q52522262 | ||
| Dissection of signaling cascades through gp130 in vivo: reciprocal roles for STAT3- and SHP2-mediated signals in immune responses. | Q52537943 | ||
| Activation of Stat-3 as one of the early events in tobacco chewing-mediated oral carcinogenesis. | Q53390216 | ||
| Stat3 cleavage by caspases: impact on full-length Stat3 expression, fragment formation, and transcriptional activity. | Q53625976 | ||
| Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling. | Q54652087 | ||
| Structural Biology of STAT3 and Its Implications for Anticancer Therapies Development. | Q55637644 | ||
| Leukaemia inhibitory factor is necessary for maintenance of haematopoietic stem cells and thymocyte stimulation | Q59080223 | ||
| Composition and assembly of STAT-targeting ubiquitin ligase complexes: paramyxovirus V protein carboxyl terminus is an oligomerization domain. | Q34438089 | ||
| Oncogenic functions of tumour suppressor p21(Waf1/Cip1/Sdi1): association with cell senescence and tumour-promoting activities of stromal fibroblasts | Q34552889 | ||
| Cucurbitacin Q: a selective STAT3 activation inhibitor with potent antitumor activity | Q34555453 | ||
| Growth inhibitory activity of cucurbitacin glucosides isolated from Citrullus colocynthis on human breast cancer cells | Q34574916 | ||
| Cucurbitacin I inhibits Stat3 and induces apoptosis in Sézary cells | Q34587181 | ||
| Mapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3. | Q34629986 | ||
| TG101209, a small molecule JAK2-selective kinase inhibitor potently inhibits myeloproliferative disorder-associated JAK2V617F and MPLW515L/K mutations | Q34633315 | ||
| A role for JAK2 mutations in myeloproliferative diseases | Q34699018 | ||
| Novel black soy peptides with antiobesity effects: activation of leptin-like signaling and AMP-activated protein kinase | Q34770053 | ||
| Importazole, a small molecule inhibitor of the transport receptor importin-β | Q35109174 | ||
| Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?. | Q35120899 | ||
| Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3. | Q35207498 | ||
| Signal transducers and activators of transcription-3 up-regulates tissue inhibitor of metalloproteinase-1 expression and decreases invasiveness of breast cancer. | Q35221996 | ||
| Mitochondrial-targeted Signal transducer and activator of transcription 3 (STAT3) protects against ischemia-induced changes in the electron transport chain and the generation of reactive oxygen species | Q35313598 | ||
| Tyrphostins: tyrosine kinase blockers as novel antiproliferative agents and dissectors of signal transduction | Q35492196 | ||
| Emerging translational approaches to target STAT3 signalling and its impact on vascular disease | Q35580177 | ||
| Pharmacological manipulation of transcription factor protein-protein interactions: opportunities and obstacles | Q35596008 | ||
| Advances in peptidic and peptidomimetic-based approaches to inhibit STAT signaling in human diseases. | Q35828729 | ||
| The role of STATs in inflammation and inflammatory diseases | Q35892913 | ||
| STAT proteins as novel targets for cancer drug discovery | Q35911116 | ||
| Recruitment of SH2-containing protein tyrosine phosphatase SHP-1 to the interleukin 2 receptor; loss of SHP-1 expression in human T-lymphotropic virus type I-transformed T cells | Q36011208 | ||
| Ulcerative colitis and autoimmunity induced by loss of myeloid alphav integrins | Q36013422 | ||
| Impairment of antigen-specific antibody production in transgenic mice expressing a dominant-negative form of gp130. | Q36047532 | ||
| Targeting Stat3 in cancer therapy | Q36147972 | ||
| Lack of toxicity of a STAT3 decoy oligonucleotide. | Q36175325 | ||
| Combined targeting of epidermal growth factor receptor, signal transducer and activator of transcription-3, and Bcl-X(L) enhances antitumor effects in squamous cell carcinoma of the head and neck. | Q36220747 | ||
| Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3' kinase/AKT pathways | Q36313178 | ||
| Local axonal function of STAT3 rescues axon degeneration in the pmn model of motoneuron disease | Q36353480 | ||
| Interleukin 6 is essential for in vivo development of B lineage neoplasms | Q36365082 | ||
| Impaired neutrophil response and CD4+ T helper cell 1 development in interleukin 6-deficient mice infected with Candida albicans | Q36366415 | ||
| Postnatally induced inactivation of gp130 in mice results in neurological, cardiac, hematopoietic, immunological, hepatic, and pulmonary defects | Q36401305 | ||
| Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells | Q36485302 | ||
| STAT3 suppresses transcription of proapoptotic genes in cancer cells with the involvement of its N-terminal domain | Q36567934 | ||
| P433 | issue | 1 | |
| P304 | page(s) | e20180160 | |
| P577 | publication date | 2020-02-10 | |
| P1433 | published in | Genetics and Molecular Biology | Q15753743 |
| P1476 | title | Targeting STAT-3 signaling pathway in cancer for development of novel drugs: Advancements and challenges | |
| P478 | volume | 43 |
Search more.