Long noncoding RNA lncARSR promotes nonalcoholic fatty liver disease and hepatocellular carcinoma by promoting YAP1 and activating the IRS2/AKT pathway

scientific article published on 13 March 2020

Long noncoding RNA lncARSR promotes nonalcoholic fatty liver disease and hepatocellular carcinoma by promoting YAP1 and activating the IRS2/AKT pathway is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1186/S12967-020-02225-Y
P932PMC publication ID7071718
P698PubMed publication ID32169080

P2093author name stringZheng Gong
Zhaoyu Liu
Ziwen Wang
Yuan Chi
He Xin
P2860cites workThe role of YAP transcription coactivator in regulating stem cell self-renewal and differentiationQ28507317
Overweight, obesity and cancer: epidemiological evidence and proposed mechanismsQ29615455
Nonalcoholic Fatty Liver Disease and Insulin Resistance: New Insights and Potential New TreatmentsQ33616887
Long noncoding RNA in liver diseasesQ33946469
Impairment of PGC-1alpha expression, neuropathology and hepatic steatosis in a transgenic mouse model of Huntington's disease following chronic energy deprivationQ34042260
Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosisQ35086389
Regulation of insulin-like growth factor signaling by Yap governs cardiomyocyte proliferation and embryonic heart sizeQ36231054
A feed-forward loop between lncARSR and YAP activity promotes expansion of renal tumour-initiating cellsQ37464844
Long Non-Coding RNA Profiling in a Non-Alcoholic Fatty Liver Disease Rodent Model: New Insight into PathogenesisQ37631409
MicroRNA-21 is a potential link between non-alcoholic fatty liver disease and hepatocellular carcinoma via modulation of the HBP1-p53-Srebp1c pathwayQ38297030
Genome-wide analysis of long noncoding RNA expression profiles in patients with non-alcoholic fatty liver diseaseQ38456347
Exosome-Transmitted lncARSR Promotes Sunitinib Resistance in Renal Cancer by Acting as a Competing Endogenous RNA.Q38775160
LATS2-mediated YAP1 phosphorylation is involved in HCC tumorigenesisQ38875112
MicroRNA Regulates Hepatocytic Differentiation of Progenitor Cells by Targeting YAP1.Q41144036
Long Noncoding RNA lncARSR Promotes Doxorubicin Resistance in Hepatocellular Carcinoma via Modulating PTEN-PI3K/Akt Pathway.Q48206950
Pathogenesis of non-alcoholic fatty liver disease mediated by YAP.Q50057357
Hippo-mediated suppression of IRS2/AKT signaling prevents hepatic steatosis and liver cancerQ50199746
Metformin improves hepatic IRS2/PI3K/Akt signaling in insulin-resistant rats of NASH and cirrhosisQ50250304
Subchronic cadmium exposure upregulates the mRNA level of genes associated to hepatic lipid metabolism in adult female CD1 mice.Q51735656
Long noncoding RNA lncARSR promotes hepatic lipogenesis via Akt/SREBP-1c pathway and contributes to the pathogenesis of nonalcoholic steatohepatitis.Q52648157
Insulin receptor substrate 2: a bridge between Hippo and AKT pathways.Q55308130
Nutraceutical Approach to Non-Alcoholic Fatty Liver Disease (NAFLD): The Available Clinical EvidenceQ56341421
lncARSR promotes liver cancer stem cells expansion via STAT3 pathwayQ58584151
LncRNA-AK012226 Is Involved in Fat Accumulation in db/db Mice Fatty Liver and Non-alcoholic Fatty Liver Disease Cell ModelQ58795421
Effects of daphnetin on lipid metabolism, insulin resistance and oxidative stress in OA‑treated HepG2 cells.Q64944611
Intensive insulin treatment induces insulin resistance in diabetic rats by impairing glucose metabolism-related mechanisms in muscle and liverQ84539920
Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver diseaseQ89220189
Knockdown of Orphan Transporter SLC22A18 Impairs Lipid Metabolism and Increases Invasiveness of HepG2 CellsQ91011762
Yes-associated protein promotes early hepatocyte cell cycle progression in regenerating liver after tissue lossQ91443850
Pinolenic acid ameliorates oleic acid-induced lipogenesis and oxidative stress via AMPK/SIRT1 signaling pathway in HepG2 cellsQ92727951
P433issue1
P921main subjectmetabolic dysfunction–associated steatotic liver diseaseQ1546498
fatty liver diseaseQ6058862
P304page(s)126
P577publication date2020-03-13
P1433published inJournal of Translational MedicineQ15716664
P1476titleLong noncoding RNA lncARSR promotes nonalcoholic fatty liver disease and hepatocellular carcinoma by promoting YAP1 and activating the IRS2/AKT pathway
P478volume18

Reverse relations

Q94671270Long noncoding RNA lncARSR confers resistance to Adriamycin and promotes osteosarcoma progressioncites workP2860

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