| scholarly article | Q13442814 |
| P356 | DOI | 10.1084/JEM.20190111 |
| P698 | PubMed publication ID | 31558613 |
| P50 | author | Bruce Beutler | Q104592 |
| Haitao Guo | Q87822141 | ||
| Douglas T Golenbock | Q89508853 | ||
| Karen P McKinnon | Q90316583 | ||
| Jenny Ting | Q50858300 | ||
| M Deng | Q83439399 | ||
| P2093 | author name string | Beverly H Koller | |
| Jason W Tam | |||
| W June Brickey | |||
| Brandon M Johnson | |||
| Hexin Shi | |||
| James S New | |||
| Austin Lenox | |||
| P2860 | cites work | Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome | Q24291856 |
| Targeting the NLRP3 inflammasome in inflammatory diseases | Q90350833 | ||
| The NLRP3 inflammasome: molecular activation and regulation to therapeutics | Q91625115 | ||
| MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition | Q92000897 | ||
| IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection | Q24302985 | ||
| The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta | Q24305136 | ||
| NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder | Q24317771 | ||
| AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC | Q24319706 | ||
| AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA | Q24319765 | ||
| An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome | Q24319799 | ||
| Mouse and human eosinophils degranulate in response to platelet-activating factor (PAF) and lysoPAF via a PAF-receptor-independent mechanism: evidence for a novel receptor | Q24629279 | ||
| Leukocyte-dependent histamine release from rabbit platelets. The role of IgE, basophils, and a platelet-activating factor | Q24679152 | ||
| Inflammasomes: mechanism of action, role in disease, and therapeutics | Q27001186 | ||
| The platelet activating factor (PAF) signaling cascade in systemic inflammatory responses | Q27693180 | ||
| Gout-associated uric acid crystals activate the NALP3 inflammasome | Q28131797 | ||
| Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf | Q28266417 | ||
| Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion | Q28270330 | ||
| Cryopyrin activates the inflammasome in response to toxins and ATP | Q28291313 | ||
| Double blind, randomised, placebo controlled study of a platelet activating factor antagonist, lexipafant, in the treatment and prevention of organ failure in predicted severe acute pancreatitis | Q28345121 | ||
| Nuclear factor E2-related factor-2 (Nrf2) is required for NLRP3 and AIM2 inflammasome activation | Q28387955 | ||
| Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf | Q28506503 | ||
| Non-canonical inflammasome activation targets caspase-11 | Q28506831 | ||
| NLRP1-dependent pyroptosis leads to acute lung injury and morbidity in mice | Q28508483 | ||
| Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages | Q28594887 | ||
| Platelet-activating factor (PAF) receptor and genetically engineered PAF receptor mutant mice | Q28609411 | ||
| Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1 | Q29614473 | ||
| Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling | Q29616024 | ||
| The inflammasome NLRs in immunity, inflammation, and associated diseases | Q29616025 | ||
| NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis | Q29616155 | ||
| Molecular identification of a danger signal that alerts the immune system to dying cells | Q29619497 | ||
| K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter | Q29620146 | ||
| Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells | Q33289420 | ||
| Platelet-activating factor and related lipid mediators | Q33916020 | ||
| Inflammatory caspases are innate immune receptors for intracellular LPS. | Q34041730 | ||
| The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP. | Q34246151 | ||
| Synaptic lipid signaling: significance of polyunsaturated fatty acids and platelet-activating factor | Q35226480 | ||
| A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. | Q35350543 | ||
| A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome Activation | Q35836862 | ||
| An NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in human macrophages | Q35860827 | ||
| Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt | Q35929017 | ||
| Mice deficient in IL-1beta manifest impaired contact hypersensitivity to trinitrochlorobenzone. | Q36366486 | ||
| Impaired anaphylactic responses with intact sensitivity to endotoxin in mice lacking a platelet-activating factor receptor | Q36400935 | ||
| Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors | Q36503546 | ||
| ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1beta and IL-18 secretion in an autocrine way | Q36725685 | ||
| NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component | Q36888222 | ||
| Human NAIP and mouse NAIP1 recognize bacterial type III secretion needle protein for inflammasome activation | Q37143484 | ||
| An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells | Q37416793 | ||
| NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages | Q37548406 | ||
| A Fluorescent Reporter Mouse for Inflammasome Assembly Demonstrates an Important Role for Cell-Bound and Free ASC Specks during In Vivo Infection. | Q37741862 | ||
| Cryopyrin-Associated Periodic Syndrome: An Update on Diagnosis and Treatment Response | Q37811988 | ||
| NLRP3 inflammasome inhibition is disrupted in a group of auto-inflammatory disease CAPS mutations | Q38750753 | ||
| Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling. | Q38835006 | ||
| Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death | Q38835009 | ||
| Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome | Q38985852 | ||
| The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. | Q39473693 | ||
| NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux | Q39607181 | ||
| NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8. | Q40250344 | ||
| K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria | Q40499822 | ||
| Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome | Q41574826 | ||
| Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock | Q41970918 | ||
| Localization and signaling of GPCRs in lipid rafts | Q42489768 | ||
| Defective NK cell activity and Th1 response in IL-18-deficient mice | Q43595287 | ||
| Noncanonical inflammasome activation by intracellular LPS independent of TLR4. | Q44450840 | ||
| The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity | Q47251504 | ||
| The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages. | Q47341459 | ||
| CD36 and Platelet-Activating Factor Receptor Promote House Dust Mite Allergy Development | Q47846762 | ||
| Platelet activating factor is elevated in cerebral spinal fluid and plasma of patients with relapsing-remitting multiple sclerosis. | Q48181308 | ||
| Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome. | Q51443610 | ||
| The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis | Q57457607 | ||
| The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection | Q58605179 | ||
| Platelet activating factor is produced during infectious peritonitis in CAPD patients | Q58831837 | ||
| Phase II multicenter clinical study of the platelet-activating factor receptor antagonist BB-882 in the treatment of sepsis | Q64127181 | ||
| The effect of the orally active platelet-activating factor antagonist WEB 2086 in the treatment of asthma | Q72398982 | ||
| Effect of recombinant human platelet-activating factor-acetylhydrolase on allergen-induced asthmatic responses | Q74139228 | ||
| Confirmatory platelet-activating factor receptor antagonist trial in patients with severe gram-negative bacterial sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial. BN 52021 Sepsis Investigator Group | Q77754946 | ||
| P433 | issue | 12 | |
| P304 | page(s) | 2838-2853 | |
| P577 | publication date | 2019-09-26 | |
| P1433 | published in | Journal of Experimental Medicine | Q3186912 |
| P1476 | title | Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFR | |
| P478 | volume | 216 |
| Q97517003 | Dexmedetomidine Enhances Autophagy via α2-AR/AMPK/mTOR Pathway to Inhibit the Activation of NLRP3 Inflammasome and Subsequently Alleviates Lipopolysaccharide-Induced Acute Kidney Injury |
| Q91807444 | Forty Years Since the Structural Elucidation of Platelet-Activating Factor (PAF): Historical, Current, and Future Research Perspectives |
| Q100444218 | Inflammasome Assays In Vitro and in Mouse Models |
| Q92188816 | Vitamin D Receptor Inhibits NLRP3 Activation by Impeding Its BRCC3-Mediated Deubiquitination |
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