| P2093 | author name string | John C Chaput | |
| | Donald H Burke | |
| | Margaret J Lange | |
| P2860 | cites work | Modulation of CpG oligodeoxynucleotide-mediated immune stimulation by locked nucleic acid (LNA). | Q47712036 |
| | Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities. | Q51030792 |
| | C-Class CpG ODN: sequence requirements and characterization of immunostimulatory activities on mRNA level. | Q51599683 |
| | TLR9 stimulation drives naïve B cells to proliferate and to attain enhanced antigen presenting function. | Q51973780 |
| | α-l-Threose Nucleic Acids as Biocompatible Antisense Oligonucleotides for Suppressing Gene Expression in Living Cells. | Q52688679 |
| | Modular cell-internalizing aptamer nanostructure enables targeted delivery of large functional RNAs in cancer cell lines. | Q55378823 |
| | Immunostimulatory CpG-oligonucleotides cause proliferation, cytokine production, and an immunogenic phenotype in chronic lymphocytic leukemia B cells | Q73386737 |
| | CpG DNA increases primary malignant B cell expression of costimulatory molecules and target antigens | Q73492223 |
| | CpG oligodeoxynucleotides stimulate IFN-gamma-inducible protein-10 production in human B cells | Q81118439 |
| | B-cell lymphomas differ in their responsiveness to CpG oligodeoxynucleotides | Q81474815 |
| | Evolution. Toward an alternative biology | Q83937530 |
| | Synthesis and Evolution of a Threose Nucleic Acid Aptamer Bearing 7-Deaza-7-Substituted Guanosine Residues | Q88395577 |
| | In vitro selection of an XNA aptamer capable of small-molecule recognition | Q90808485 |
| | CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma | Q24568172 |
| | Chemical etiology of nucleic acid structure: the alpha-threofuranosyl-(3'-->2') oligonucleotide system | Q28137995 |
| | XNA marks the spot. What can we learn about the origins of life and the treatment of disease through artificial nucleic acids? | Q28706271 |
| | Comparison of human B cell activation by TLR7 and TLR9 agonists | Q33354786 |
| | Deoxycytidyl-deoxyguanosine oligonucleotide classes A, B, and C induce distinct cytokine gene expression patterns in rhesus monkey peripheral blood mononuclear cells and distinct alpha interferon responses in TLR9-expressing rhesus monkey plasmacyto | Q33788621 |
| | Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition | Q33930537 |
| | Toll-like receptor 9 signaling by CpG-B oligodeoxynucleotides induces an apoptotic pathway in human chronic lymphocytic leukemia B cells | Q33931707 |
| | Synthetic genetic polymers capable of heredity and evolution | Q34031569 |
| | CpG motifs in bacterial DNA trigger direct B-cell activation | Q34307394 |
| | Clinical evaluation of CpG oligonucleotides as adjuvants for vaccines targeting infectious diseases and cancer | Q34613585 |
| | Robust suppression of HIV replication by intracellularly expressed reverse transcriptase aptamers is independent of ribozyme processing | Q36460462 |
| | The role of UNC93B1 protein in surface localization of TLR3 receptor and in cell priming to nucleic acid agonists | Q36508677 |
| | TLR9-mediated recognition of DNA. | Q37028821 |
| | Heterogeneity of Toll-like receptor 9 signaling in B cell malignancies and its potential therapeutic application | Q37671216 |
| | RNA:DNA hybrids are a novel molecular pattern sensed by TLR9. | Q37707494 |
| | Towards XNA nanotechnology: new materials from synthetic genetic polymers | Q38205549 |
| | CpG motif-independent activation of TLR9 upon endosomal translocation of "natural" phosphodiester DNA. | Q38316638 |
| | Mechanism and function of a newly identified CpG DNA motif in human primary B cells | Q38316819 |
| | Endosomal translocation of vertebrate DNA activates dendritic cells via TLR9-dependent and -independent pathways | Q38326606 |
| | Darwinian evolution of an alternative genetic system provides support for TNA as an RNA progenitor. | Q38327534 |
| | Cutting edge: species-specific TLR9-mediated recognition of CpG and non-CpG phosphorothioate-modified oligonucleotides | Q38332386 |
| | Rational design of new CpG oligonucleotides that combine B cell activation with high IFN-alpha induction in plasmacytoid dendritic cells | Q38354073 |
| | The immunostimulatory activity of phosphorothioate CpG oligonucleotides is affected by distal sequence changes | Q39591576 |
| | Toll-like receptor agonists synergistically increase proliferation and activation of B cells by epstein-barr virus. | Q39609877 |
| | Raji B cells, misidentified as THP-1 cells, stimulate DC-SIGN-mediated HIV transmission | Q40588249 |
| | Distinct TLR-mediated cytokine production and immunoglobulin secretion in human newborn naïve B cells | Q40649303 |
| | Phosphorothioate backbone modification modulates macrophage activation by CpG DNA. | Q40848499 |
| | Structural Insights into Conformation Differences between DNA/TNA and RNA/TNA Chimeric Duplexes | Q41730004 |
| | Reconstruction of Toll-like receptor 9-mediated responses in HEK-Blue hTLR9 cells by transfection of human macrophage scavenger receptor 1 gene. | Q42652831 |
| | Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation | Q42767195 |
| | DNA polymerase-mediated DNA synthesis on a TNA template | Q44284574 |
| | A Scalable Synthesis of α-L-Threose Nucleic Acid Monomers | Q45195581 |
| | Evaluating TNA stability under simulated physiological conditions | Q46112721 |
| | Structural basis for TNA synthesis by an engineered TNA polymerase | Q46171063 |
| | Reverse Transcription of Threose Nucleic Acid by a Naturally Occurring DNA Polymerase | Q46182167 |
| | Phosphodiester backbone of the CpG motif within immunostimulatory oligodeoxynucleotides augments activation of Toll-like receptor 9. | Q46259445 |
| | The structure of a TNA-TNA complex in solution: NMR study of the octamer duplex derived from alpha-(L)-threofuranosyl-(3'-2')-CGAATTCG. | Q46312041 |
| P433 | issue | 1 | |
| P304 | page(s) | 51-59 | |
| P577 | publication date | 2018-12-11 | |
| P1433 | published in | Nucleic Acid Therapeutics | Q19297428 |
| P1476 | title | Activation of Innate Immune Responses by a CpG Oligonucleotide Sequence Composed Entirely of Threose Nucleic Acid | |
| P478 | volume | 29 | |