| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Eleanor J Molloy | |
| Derek G Doherty | |||
| Dean Huggard | |||
| P2860 | cites work | Updated national birth prevalence estimates for selected birth defects in the United States, 2004-2006 | Q22252926 |
| γδ T Cells Link Innate and Adaptive Immune Responses | Q22306426 | ||
| Periodontal disease's contribution to Alzheimer's disease progression in Down syndrome | Q26744852 | ||
| CD4+/CD8+ double-positive T cells: more than just a developmental stage? | Q26821885 | ||
| Impaired in vitro response of circulating lymphocytes to phytohemagglutinin in Down's syndrome: dose- and time-response curves and relation to cellular immunity | Q68465947 | ||
| Heterogeneity of human blood monocytes: the CD14+ CD16+ subpopulation | Q71648991 | ||
| Nonspecific immunity in down syndrome: A study of chemotaxis, phagocytosis, oxidative metabolism, and cell surface marker expression of polymorphonuclear cells | Q72092295 | ||
| Natural killer cell function in trisomy-21 (Down's syndrome) | Q72667495 | ||
| Association of decreased T-cell-mediated natural cytotoxicity and interferon production in Down's syndrome | Q72750155 | ||
| Defective monocyte chemotaxis in children with Down's syndrome | Q72785877 | ||
| Lymphocyte subpopulations in Down's syndrome: high percentage of circulating HNK-1+, Leu 2a+ cells | Q72819800 | ||
| Modulation of tissue Toll-like receptor 2 and 4 during the early phases of polymicrobial sepsis correlates with mortality | Q73496946 | ||
| Gammadelta T cells promote anterior chamber-associated immune deviation and immune privilege through their production of IL-10 | Q79401053 | ||
| Autoantibodies in patients with Down syndrome: early senescence of the immune system or precocious markers for immunological diseases? | Q81419788 | ||
| Intrinsic abnormalities of lymphocyte counts in children with down syndrome | Q81630610 | ||
| Analysis of peripheral blood T-cell subsets, natural killer cells and serum levels of cytokines in children with Down syndrome | Q84240723 | ||
| Increased circulating apoptotic lymphocytes in children with Down syndrome | Q84587288 | ||
| Expression of HIF-1 alpha, VEGF and EPO in peripheral blood from patients with two cardiac abnormalities associated with hypoxia | Q84632836 | ||
| Decreased response after conjugated meningococcal serogroup C vaccination in children with Down syndrome | Q84784101 | ||
| Influenza A/H1N1 vaccination response is inadequate in down syndrome children when the latest cut-off values are used | Q84984503 | ||
| TLR-2 and TLR-4 expression in monocytes of newborns with late-onset sepsis | Q87985108 | ||
| Pidotimod, an immunostimulant in pediatric recurrent respiratory tract infections: A meta-analysis of randomized controlled trials | Q90361970 | ||
| Altered Toll-Like Receptor Signalling in Children with Down Syndrome | Q90704366 | ||
| Increased systemic inflammation in children with Down syndrome | Q91566124 | ||
| Viral Bacterial Interactions in Children: Impact on Clinical Outcomes | Q92792742 | ||
| Defective neutrophil chemotaxis in Down's syndrome patients and its relationship to periodontal destruction | Q93512400 | ||
| Role of gamma-delta (γδ) T cells in autoimmunity | Q27008187 | ||
| NLRP3 inflammasome and its inhibitors: a review | Q27023333 | ||
| Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis | Q28246968 | ||
| The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling | Q29615457 | ||
| Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Clinical Trial | Q30278079 | ||
| Innate immune function and mortality in critically ill children with influenza: a multicenter study | Q30418318 | ||
| Small molecule-mediated activation of the integrin CD11b/CD18 reduces inflammatory disease | Q30658251 | ||
| Phenotype, function, and differentiation potential of human monocyte subsets. | Q33606028 | ||
| Respiratory morbidity of hospitalized children with Trisomy 21. | Q33717584 | ||
| Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic and allogeneic tumors. II. Characterization of effector cells | Q33901387 | ||
| Toll-like receptor 4 monoclonal antibody attenuates lipopolysaccharide-induced acute lung injury in mice | Q33962168 | ||
| The CD14+ CD16+ blood monocytes: their role in infection and inflammation | Q34585882 | ||
| Cytokines, inflammation, and pain | Q34618022 | ||
| Hospital admissions in children with down syndrome: experience of a population-based cohort followed from birth. | Q34962457 | ||
| Efficacy and optimization of palivizumab injection regimens against respiratory syncytial virus infection | Q35347139 | ||
| Pidotimod: the state of art | Q35633600 | ||
| miRNA-155 upregulation and complement factor H deficits in Down's syndrome. | Q35690949 | ||
| Temporal accrual of complement proteins in amyloid plaques in Down's syndrome with Alzheimer's disease | Q35745403 | ||
| Cytokine profile in severe Gram-positive and Gram-negative abdominal sepsis. | Q35746498 | ||
| Reduced numbers of switched memory B cells with high terminal differentiation potential in Down syndrome. | Q36361480 | ||
| B cells and beyond: therapeutic opportunities targeting inflammation | Q36952419 | ||
| The effect of complement depletion on lung clearance of bacteria | Q37030806 | ||
| Oxidative burst intensity of peripheral phagocytic cells and periodontitis in Down syndrome | Q37067491 | ||
| Phenotype of apoptotic lymphocytes in children with Down syndrome | Q37133997 | ||
| Trisomy 21 consistently activates the interferon response. | Q37235217 | ||
| The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress. | Q37374914 | ||
| Intrinsic defect of the immune system in children with Down syndrome: a review. | Q37403728 | ||
| Limited Evidence on the Management of Respiratory Tract Infections in Down's Syndrome: A Systematic Review | Q37458090 | ||
| Immune evaluation and vaccine responses in Down syndrome: evidence of immunodeficiency? | Q37540591 | ||
| The role of toll-like receptors in chronic inflammation | Q37616733 | ||
| Down syndrome as risk factor for respiratory syncytial virus hospitalization: A prospective multicenter epidemiological study. | Q37638396 | ||
| Unraveling the complexity of neurodegeneration in brains of subjects with Down syndrome: insights from proteomics. | Q37662773 | ||
| Regulatory T cells (Treg) and Their Roles in Immune System with Respect to Immunopathological Disorders | Q37776686 | ||
| MicroRNAs: the fine-tuners of Toll-like receptor signalling | Q37844405 | ||
| Infections and immunodeficiency in Down syndrome | Q37847219 | ||
| The inflammasome: an integrated view | Q37925072 | ||
| The three human monocyte subsets: implications for health and disease | Q37995036 | ||
| Dissecting negative regulation of Toll-like receptor signaling | Q38020637 | ||
| Targeting interleukin-6: all the way to treat autoimmune and inflammatory diseases | Q38058508 | ||
| Why do we need IgM memory B cells? | Q38105446 | ||
| Trisomy 21--incidence and outcomes in the first year, in Ireland today | Q38256761 | ||
| Risk factors associated with death in patients with severe respiratory syncytial virus infection | Q38274343 | ||
| Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality. | Q38483410 | ||
| Early innate immune responses to bacterial LPS. | Q38795578 | ||
| Dementia in Down's syndrome | Q38865366 | ||
| Persistent antigen and germinal center B cells sustain T follicular helper cell responses and phenotype | Q39180411 | ||
| Neutrophils and Immunity: From Bactericidal Action to Being Conquered. | Q39181244 | ||
| Multiple potential regulatory sites of TLR4 activation induced by LPS as revealed by novel inhibitory human TLR4 mAbs | Q39365012 | ||
| Down's syndrome is a risk factor for severe lower respiratory tract infection due to respiratory syncytial virus | Q39477810 | ||
| Quantitative, Phenotypical, and Functional Characterization of Cellular Immunity in Children and Adolescents With Down Syndrome | Q40257062 | ||
| Risk of death for children with down syndrome and sepsis | Q40364942 | ||
| Antagonistic antibody prevents toll-like receptor 2-driven lethal shock-like syndromes | Q40555496 | ||
| Prophylaxis with the novel immunomodulator pidotimod reduces the frequency and severity of upper respiratory tract infections in children with Down's syndrome | Q40638818 | ||
| Clinical and Immunological Benefits of OM-85 Bacterial Lysate in Patients with Allergic Rhinitis, Asthma, and COPD and Recurrent Respiratory Infections | Q40697828 | ||
| Immunological features of Down's syndrome: a review | Q40722699 | ||
| Generation of switched memory B cells in response to vaccination in Down syndrome children and their siblings | Q40929784 | ||
| Non-Classical monocytes display inflammatory features: Validation in Sepsis and Systemic Lupus Erythematous | Q41006064 | ||
| Children with Down syndrome are high-risk for severe respiratory syncytial virus disease | Q41539079 | ||
| Increased production of interleukin-10 in children with Down syndrome upon ex vivo stimulation with Streptococcus pneumoniae. | Q42244190 | ||
| Immunogenicity and safety of an inactivated hepatitis A vaccine in children with Down syndrome | Q42636837 | ||
| Complement association with neurons and beta-amyloid deposition in the brains of aged individuals with Down Syndrome | Q43573861 | ||
| Follow-up study of immune defects in patients with dysmorphic disorders | Q43692809 | ||
| Altered T-cell subsets and defective T-cell function in young children with Down syndrome (trisomy-21). | Q43767780 | ||
| Trisomy 21 causes changes in the circulating proteome indicative of chronic autoinflammation. | Q44645053 | ||
| Functionality of the pneumococcal antibody response in Down syndrome subjects. | Q44650363 | ||
| Analysis of blood cell populations, plasma zinc and natural killer cell activity in young children with Down's syndrome. | Q45118012 | ||
| Altered cytokine and acute phase response protein levels in the blood of children with Downs syndrome: relationship with dementia of Alzheimer's type | Q45255505 | ||
| Lymphocytes bearing the gamma/delta T-cell receptors in Down's syndrome | Q45263894 | ||
| Increased pro-inflammatory cytokine production in Down Syndrome children upon stimulation with live influenza A virus | Q45361072 | ||
| Down syndrome B-lymphocyte subpopulations, intrinsic defect or decreased T-lymphocyte help. | Q45901946 | ||
| Aberrations in circulating inflammatory cytokine levels in patients with Down syndrome: a meta-analysis | Q47120293 | ||
| The burden of respiratory syncytial virus (RSV) associated acute lower respiratory infections in children with Down syndrome: A systematic review and meta-analysis | Q47162230 | ||
| Broncho-Vaxom in pediatric recurrent respiratory tract infections: A systematic review and meta-analysis | Q47446260 | ||
| Complement factor H, a marker of self protects against experimental autoimmune encephalomyelitis | Q48696531 | ||
| The pro-inflammatory phenotype of the human non-classical monocyte subset is attributed to senescence | Q49958269 | ||
| Differential expression of NLRP3 among hematopoietic cells | Q50528108 | ||
| Impaired avidity maturation after tetanus toxoid booster in children with Down syndrome | Q51031180 | ||
| Severe impairment of secretory Ig production in parotid saliva of Down Syndrome individuals. | Q51711840 | ||
| Comorbidity, hospitalization, and medication use and their influence on mental and motor development of young infants with Down syndrome. | Q51911961 | ||
| Homeostatic cytokines and expansion of regulatory T cells accompany thymic impairment in children with Down syndrome. | Q51965886 | ||
| Patterns of lymphokine secretion amongst mouse gamma delta T cell clones. | Q52896354 | ||
| Distinct abnormalities in the innate immune system of children with Down syndrome. | Q53340653 | ||
| CD14+CD16+ monocytes in the course of sepsis in neonates and small children: monitoring and functional studies. | Q54545053 | ||
| Toll-Like Receptor 2 Signaling and Current Approaches for Therapeutic Modulation in Synucleinopathies. | Q54752771 | ||
| Immunological patterns in young children with Down syndrome: is there a temporal trend? | Q56994365 | ||
| Altered endotoxin responsiveness in healthy children with Down syndrome | Q58613664 | ||
| Hospitalization for Respiratory Syncytial Virus in Children with Down Syndrome Less than 2 Years of Age: A Systematic Review and Meta-Analysis | Q59351651 | ||
| Down Syndrome and the Risk of Severe RSV Infection: A Meta-analysis | Q59354832 | ||
| Thymic Epithelium Abnormalities in DiGeorge and Down Syndrome Patients Contribute to Dysregulation in T Cell Development | Q64086713 | ||
| Age-related expansion of functionally inefficient cells with markers of natural killer activity in Down's syndrome | Q67898043 | ||
| Derangement of non-specific immunity in Down syndrome subjects: low leukocyte chemiluminescence activity after phagocytic activation | Q68439939 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P921 | main subject | Down syndrome | Q47715 |
| P304 | page(s) | 73 | |
| P577 | publication date | 2020-02-27 | |
| P1433 | published in | Frontiers in pediatrics | Q27725038 |
| P1476 | title | Immune Dysregulation in Children With Down Syndrome | |
| P478 | volume | 8 |
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