An abundant quiescent stem cell population in Drosophila Malpighian tubules protects principal cells from kidney stones

scientific article published on 16 March 2020

An abundant quiescent stem cell population in Drosophila Malpighian tubules protects principal cells from kidney stones is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.7554/ELIFE.54096
P932PMC publication ID7093152
P698PubMed publication ID32175841

P50authorChenhui WangQ90351482
Allan C SpradlingQ90351488
P2860cites workKidney stone diseaseQ24536113
Chronic kidney disease in kidney stone formersQ24617170
Kidney stones: a global picture of prevalence, incidence, and associated risk factorsQ24620342
Twin-spot MARCM to reveal the developmental origin and identity of neuronsQ24657587
Function-informed transcriptome analysis of Drosophila renal tubuleQ24801721
Gastrointestinal stem cells in health and disease: from flies to humansQ26750514
A Drosophila model identifies a critical role for zinc in mineralization for kidney stone diseaseQ27309206
Notch-Delta signaling induces a transition from mitotic cell cycle to endocycle in Drosophila follicle cellsQ28208451
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAPQ28266862
Df31 Protein and snoRNAs Maintain Accessible Higher-Order Structures of ChromatinQ29398056
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2Q29547403
Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesisQ29615747
A combined ex vivo and in vivo RNAi screen for notch regulators in Drosophila reveals an extensive notch interaction network.Q33584616
Coexistence of quiescent and active adult stem cells in mammalsQ33926891
Differentiated kidney epithelial cells repair injured proximal tubule.Q34038540
Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells.Q34146136
featureCounts: an efficient general purpose program for assigning sequence reads to genomic featuresQ34384848
A novel Drosophila alkaline phosphatase specific to the ellipsoid body of the adult brain and the lower Malpighian (renal) tubuleQ34608609
Intrinsic epithelial cells repair the kidney after injuryQ34765013
Repair of injured proximal tubule does not involve specialized progenitorsQ35022127
Nonautonomous regulation of Drosophila midgut stem cell proliferation by the insulin-signaling pathwayQ35558600
Role of caudal in hindgut specification and gastrulation suggests homology between Drosophila amnioproctodeal invagination and vertebrate blastopore.Q47071770
Identification and functional characterization of muscle satellite cells in Drosophila.Q47149380
Muscle Stem Cells Undergo Extensive Clonal Drift during Tissue Growth via Meox1-Mediated Induction of G2 Cell-Cycle ArrestQ47310317
Ferritin accumulation under iron scarcity in Drosophila iron cellsQ47736632
Interorgan regulation of Drosophila intestinal stem cell proliferation by a hybrid organ boundary zone.Q47744509
Evidence that a copper-metallothionein complex is responsible for fluorescence in acid-secreting cells of the Drosophila stomachQ49295382
Mechanical regulation of stem-cell differentiation by the stretch-activated Piezo channelQ50133588
Differential Notch activity is required for homeostasis of malpighian tubules in adult DrosophilaQ50442850
GFP reporters detect the activation of the Drosophila JAK/STAT pathway in vivoQ50713720
Morphological and molecular characterization of adult midgut compartmentalization in DrosophilaQ51020236
Puckered-GAL4 driving in JNK-active cells.Q52114455
In situ activation pattern of Drosophila EGF receptor pathway during development.Q52192958
[Studies on the chemical nature and formation of the urinary conglomerate in the Malpighian vessels of the rosy mutant of Drosophila melanogaster].Q52474375
Fluid Reabsorption And Ion Transport By The Lower Malpighian Tubules Of Adult Female DrosophilaQ52537684
The malpighian tubules of Drosophila melanogaster: a novel phenotype for studies of fluid secretion and its control.Q52540434
Dual origin of the renal tubules in Drosophila: mesodermal cells integrate and polarize to establish secretory function.Q52608351
Hypoxanthine in rosy and maroon-like mutants of Drosophila melanogaster.Q52622905
Multipotent Drosophila intestinal stem cells specify daughter cell fates by differential notch signaling.Q52676885
Endocycle-related tubular cell hypertrophy and progenitor proliferation recover renal function after acute kidney injury.Q52720504
Cell cycle heterogeneity directs the timing of neural stem cell activation from quiescence.Q52721264
Ingestion of Food Particles Regulates the Mechanosensing Misshapen-Yorkie Pathway in Drosophila Intestinal Growth.Q54110206
Temporospatial induction of homeodomain gene cut dictates natural lineage reprogramming.Q54979568
A population of adult satellite-like cells in Drosophila is maintained through a switch in RNA-isoforms.Q55087393
Anatomy and Physiology of the Digestive Tract ofQ57055358
Dietary Lipids Modulate Notch Signaling and Influence Adult Intestinal Development and Metabolism in DrosophilaQ57294150
Fizzy-Related dictates A cell cycle switch during organ repair and tissue growth responses in the hindgutQ58767835
Polyploidy in tissue homeostasis and regenerationQ90321024
Comprehensive Integration of Single-Cell DataQ92614138
Surviving Acute Organ Failure: Cell Polyploidization and Progenitor ProliferationQ92762910
In vivo clonal analysis reveals lineage-restricted progenitor characteristics in mammalian kidney development, maintenance, and regeneration.Q35586384
Altered modes of stem cell division drive adaptive intestinal growthQ35633862
Copper cells and stomach acid secretion in the Drosophila midgutQ35733122
The adult Drosophila malpighian tubules are maintained by multipotent stem cellsQ36088912
Age-related changes in Drosophila midgut are associated with PVF2, a PDGF/VEGF-like growth factorQ36691494
Molecular characterization of the Drosophila melanogaster urate oxidase gene, an ecdysone-repressible gene expressed only in the malpighian tubulesQ36727357
Cooperative functions of the reaper and head involution defective genes in the programmed cell death of Drosophila central nervous system midline cellsQ36766071
Functional domains are specified to single-cell resolution in a Drosophila epitheliumQ36769041
Migration of Drosophila intestinal stem cells across organ boundariesQ36783098
Physiological and stem cell compartmentalization within the Drosophila midgutQ37126956
Tissue damage-induced intestinal stem cell division in DrosophilaQ37137625
Salty dog, an SLC5 symporter, modulates Drosophila response to salt stressQ37140871
Molecular regulation of stem cell quiescence.Q37256787
Insect homeostasis: past and futureQ37371436
Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in DrosophilaQ37379590
The Drosophila hindgut lacks constitutively active adult stem cells but proliferates in response to tissue damageQ37410616
Notch-dependent downregulation of the homeodomain gene cut is required for the mitotic cycle/endocycle switch and cell differentiation in Drosophila follicle cellsQ37478720
Epithelial ultrastructure and cellular mechanisms of acid and base transport in the Drosophila midgutQ37485512
Polyploidization and cell fusion contribute to wound healing in the adult Drosophila epitheliumQ37501809
Pathogenic stimulation of intestinal stem cell response in DrosophilaQ37730965
Drosophila stem cell niches: a decade of discovery suggests a unified view of stem cell regulation.Q37901791
Endocycles: a recurrent evolutionary innovation for post-mitotic cell growth.Q38189970
Intestinal stem cell response to injury: lessons from DrosophilaQ38823324
Maintenance of the adult Drosophila intestine: all roads lead to homeostasisQ38890305
Fly-FUCCI: A versatile tool for studying cell proliferation in complex tissues.Q39004984
Drosophila Malpighian Tubules: A Model for Understanding Kidney Development, Function, and DiseaseQ39242400
JNK activity in somatic stem cells causes loss of tissue homeostasis in the aging Drosophila gut.Q39405395
Tissue homeostasis and aging: new insight from the fly intestine.Q39442257
Classical xanthinuria: a rare cause of pediatric urolithiasisQ40586650
Sox9-Positive Progenitor Cells Play a Key Role in Renal Tubule Epithelial Regeneration in MiceQ40911733
Regional Cell-Specific Transcriptome Mapping Reveals Regulatory Complexity in the Adult Drosophila Midgut.Q41121635
EGFR/MAPK signaling regulates the proliferation of Drosophila renal and nephric stem cellsQ41529777
Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgutQ42077813
Ultrastructure of the copper-accumulating region of the Drosophila larval midgut.Q42438977
Characterization of renal progenitors committed toward tubular lineage and their regenerative potential in renal tubular injuryQ42649770
Cell-specific inositol 1,4,5 trisphosphate 3-kinase mediates epithelial cell apoptosis in response to oxidative stress in DrosophilaQ43198760
Drosophila intestinal response to bacterial infection: activation of host defense and stem cell proliferationQ45097924
Regulatory peptides in fruit fly midgutQ46274875
Sox9 Activation Highlights a Cellular Pathway of Renal Repair in the Acutely Injured Mammalian KidneyQ46902699
P4510describes a project that usesImageJQ1659584
DESeq2Q113018293
P921main subjectstem-cell quiescenceQ125311828
P577publication date2020-03-16
P1433published ineLifeQ2000008
P1476titleAn abundant quiescent stem cell population in Drosophila Malpighian tubules protects principal cells from kidney stones
P478volume9

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cites work (P2860)
Q108589105Characteristics and Therapeutic Potential of Human Amnion-Derived Stem Cells
Q112639168DRscDB: A single-cell RNA-seq resource for data mining and data comparison across species
Q91727255The Septate Junction Protein Tetraspanin 2A is critical to the Structure and Function of Malpighian tubules in Drosophila melanogaster

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