scholarly article | Q13442814 |
P50 | author | Kabirul Islam | Q88336855 |
P2093 | author name string | Babu Sudhamalla | |
Simran Arora | |||
Sinan Wang | |||
Sam Kavoosi | |||
Valerie Snyder | |||
P2860 | cites work | The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase | Q24299948 |
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2 | Q24306181 | ||
Crystal structure of TET2-DNA complex: insight into TET-mediated 5mC oxidation | Q24311603 | ||
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1 | Q24316558 | ||
Hydroquinone increases 5-hydroxymethylcytosine formation through ten eleven translocation 1 (TET1) 5-methylcytosine dioxygenase | Q24614496 | ||
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine | Q24614582 | ||
Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA | Q24622718 | ||
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA | Q24632387 | ||
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases | Q24632807 | ||
Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells | Q24683296 | ||
Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes | Q26829985 | ||
Chemical methods for decoding cytosine modifications in DNA | Q27003288 | ||
Staurosporine-Derived Inhibitors Broaden the Scope of Analog-Sensitive Kinase Technology | Q27680486 | ||
Crystal structure of the RNA demethylase ALKBH5 from zebrafish | Q27681862 | ||
Structural and functional analysis of JMJD2D reveals molecular basis for site-specific demethylation among JMJD2 demethylases | Q27683568 | ||
Structural insight into substrate preference for TET-mediated oxidation | Q27702550 | ||
WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation | Q28255707 | ||
Expanding chemical biology of 2-oxoglutarate oxygenases | Q28268841 | ||
A chemical switch for inhibitor-sensitive alleles of any protein kinase | Q29614785 | ||
Active demethylation of the paternal genome in the mouse zygote | Q33901068 | ||
Sensitive and specific single-molecule sequencing of 5-hydroxymethylcytosine. | Q34029463 | ||
Active DNA demethylation: many roads lead to Rome. | Q34129576 | ||
Magic bullets for protein kinases | Q34221212 | ||
Chemical biology. A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probes | Q34443912 | ||
Generation of a conditional analog-sensitive kinase in human cells using CRISPR/Cas9-mediated genome engineering | Q36239605 | ||
TET family proteins: oxidation activity, interacting molecules, and functions in diseases | Q36668364 | ||
Opposing Chromatin Signals Direct and Regulate the Activity of Lysine Demethylase 4C (KDM4C). | Q36744726 | ||
FTO-mediated formation of N6-hydroxymethyladenosine and N6-formyladenosine in mammalian RNA. | Q36856390 | ||
Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells | Q37543786 | ||
Engineered Split-TET2 Enzyme for Inducible Epigenetic Remodeling. | Q37743269 | ||
Oxygen, epigenetic signaling, and the evolution of early life | Q38085926 | ||
Allele-specific chemical genetics: concept, strategies, and applications | Q38273198 | ||
Engineering the substrate specificity of ADP-ribosyltransferases for identifying direct protein targets | Q41153612 | ||
Chemical genetic discovery of PARP targets reveals a role for PARP-1 in transcription elongation | Q41218811 | ||
Studies on the catalytic domains of multiple JmjC oxygenases using peptide substrates | Q41520051 | ||
Lysine demethylase KDM2A inhibits TET2 to promote DNA methylation and silencing of tumor suppressor genes in breast cancer | Q41701650 | ||
Design of allele-specific protein methyltransferase inhibitors | Q43804780 | ||
Chemical genetics: where genetics and pharmacology meet | Q46192463 | ||
Selective inhibition of factor inhibiting hypoxia-inducible factor | Q46507004 | ||
Mutations along a TET2 active site scaffold stall oxidation at 5-hydroxymethylcytosine. | Q48180112 | ||
A rapid mass spectrometric method for the measurement of catalytic activity of ten-eleven translocation enzymes. | Q50925680 | ||
Engineering Biological C-H Functionalization Leads to Allele-Specific Regulation of Histone Demethylases. | Q51144415 | ||
Thioether Macrocyclic Peptides Selected against TET1 Compact Catalytic Domain Inhibit TET1 Catalytic Activity. | Q52718797 | ||
Mechanism and Stem-Cell Activity of 5-Carboxycytosine Decarboxylation Determined by Isotope Tracing | Q57376743 | ||
A click chemistry approach to tetrazoles by Huisgen 1,3-dipolar cycloaddition: synthesis of 5-sulfonyl tetrazoles from azides and sulfonyl cyanides | Q84545888 | ||
Modular synthesis of cell-permeating 2-ketoglutarate esters | Q87193254 | ||
P433 | issue | 32 | |
P407 | language of work or name | English | Q1860 |
P1104 | number of pages | 7 | |
P304 | page(s) | 10263-10269 | |
P577 | publication date | 2018-08-02 | |
P1433 | published in | Journal of the American Chemical Society | Q898902 |
P1476 | title | Complementary Steric Engineering at the Protein-Ligand Interface for Analogue-Sensitive TET Oxygenases | |
P478 | volume | 140 |
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