Deep sequencing and pathway-focused analysis revealed multigene oncodriver signatures predicting survival outcomes in advanced colorectal cancer

scientific article published on 22 July 2018

Deep sequencing and pathway-focused analysis revealed multigene oncodriver signatures predicting survival outcomes in advanced colorectal cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41389-018-0066-2
P932PMC publication ID6054833
P698PubMed publication ID30032163

P50authorMaddalena BarbaQ28039199
Patrizia ViciQ28833492
Francesca SperatiQ56420560
Carla Azzurra AmoreoQ56451561
Matteo PalloccaQ58146299
Ruggero De MariaQ64679020
Beatrice CasiniQ90284185
Maurizio FanciulliQ91253142
Laura PizzutiQ96133253
Frauke GoemanQ96255714
Maria Grazia DiodoroQ100416030
Edoardo PescarmonaQ114372544
Marco MazzottaQ114372545
Elisa MelucciQ38642642
Gennaro CilibertoQ38800176
Enzo GalloQ47504550
P2093author name stringLuigi Di Lauro
Domenico Sergi
Marcello Maugeri-Saccà
Simonetta Buglioni
Francesca De Nicola
P2860cites workUbiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesisQ22122362
Cancer genome landscapesQ22242276
Comprehensive molecular characterization of human colon and rectal cancerQ24630415
A genetic model for colorectal tumorigenesisQ27860582
Identification and expansion of human colon-cancer-initiating cellsQ27860627
PD-1 Blockade in Tumors with Mismatch-Repair DeficiencyQ28262647
Genetic alterations during colorectal-tumor developmentQ28281200
Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancerQ28298328
Stepwise deletions of polyA sequences in mismatch repair-deficient colorectal cancersQ28507252
A novel clinical prognostic score incorporating the number of resected lymph-nodes to predict recurrence and survival in non-small-cell lung cancerQ61899429
Genetic Interactions in Cancer Progression and TreatmentQ63383811
Targeting PI3K signalling in cancer: opportunities, challenges and limitationsQ29617685
Microsatellite instability in cancer of the proximal colonQ29620692
Prognostic role of tumor PIK3CA mutation in colorectal cancer: a systematic review and meta-analysisQ30248900
Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesionsQ34304263
Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade.Q34557699
Novel recurrently mutated genes and a prognostic mutation signature in colorectal cancerQ35351133
CHK1-targeted therapy to deplete DNA replication-stressed, p53-deficient, hyperdiploid colorectal cancer stem cellsQ36340540
Impact of deleterious passenger mutations on cancer progressionQ36637272
Genomic Correlates of Immune-Cell Infiltrates in Colorectal CarcinomaQ36850230
Recurrent R-spondin fusions in colon cancerQ36949683
A multigene mutation classification of 468 colorectal cancers reveals a prognostic role for APC.Q37017721
Analysis of the hippo transducers TAZ and YAP in cervical cancer and its microenvironment.Q37079126
Targeted therapy in metastatic colorectal cancer -- an example of personalised medicine in action.Q38078599
The role of the PI3K pathway in colorectal cancer.Q38319557
Synthetic lethality and cancer.Q38709651
Cancer type-dependent genetic interactions between cancer driver alterations indicate plasticity of epistasis across cell typesQ40676447
The WTX Tumor Suppressor Enhances p53 Acetylation by CBP/p300Q42557316
REporting recommendations for tumour MARKer prognostic studies (REMARK).Q43854401
Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor geneQ46284220
BRAF mutant colorectal cancer: prognosis, treatment, and new perspectivesQ47767987
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue7
P921main subjectcolorectal cancerQ188874
P304page(s)55
P577publication date2018-07-22
P1433published inOncogenesisQ27724395
P1476titleDeep sequencing and pathway-focused analysis revealed multigene oncodriver signatures predicting survival outcomes in advanced colorectal cancer
P478volume7

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cites work (P2860)
Q64243391A Simplified Genomic Profiling Approach Predicts Outcome in Metastatic Colorectal Cancer
Q95841159Clinical Multigene Panel Sequencing Identifies Distinct Mutational Association Patterns in Metastatic Colorectal Cancer
Q132041261In Silico Deciphering of the Potential Impact of Variants of Uncertain Significance in Hereditary Colorectal Cancer Syndromes
Q104617780Multicohort and cross-platform validation of a prognostic Wnt signature in colorectal cancer

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