Epstein-Barr Virus Epitope-Major Histocompatibility Complex Interaction Combined with Convergent Recombination Drives Selection of Diverse T Cell Receptor α and β Repertoires

scientific article published on 17 March 2020

Epstein-Barr Virus Epitope-Major Histocompatibility Complex Interaction Combined with Convergent Recombination Drives Selection of Diverse T Cell Receptor α and β Repertoires is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MBIO.00250-20
P932PMC publication ID7078470
P698PubMed publication ID32184241

P2093author name stringDario Ghersi
Liisa K Selin
Katherine Luzuriaga
Nuray Aslan
Anna Gil
Ramakanth Chirravuri-Venkata
Fransenio Clark
Larisa Kamga
P2860cites workA human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chainsQ24301420
Hepatitis C virus immune escape via exploitation of a hole in the T cell repertoireQ27489598
The structural dynamics and energetics of an immunodominant T cell receptor are programmed by its Vbeta domainQ27649862
Genetic and Structural Basis for Selection of a Ubiquitous T Cell Receptor Deployed in Epstein-Barr Virus InfectionQ27666160
Fitting a mixture model by expectation maximization to discover motifs in biopolymersQ27860556
αβ T cell receptors as predictors of health and diseaseQ28088357
A small jab - a big effect: nonspecific immunomodulation by vaccinesQ28290778
Circos: an information aesthetic for comparative genomicsQ29547653
Cytomegalovirus infection enhances the immune response to influenza.Q30300254
Epstein-Barr virus and multiple sclerosis: potential opportunities for immunotherapyQ30878158
Biology and disease associations of Epstein-Barr virusQ33772230
Sequence and Structural Analyses Reveal Distinct and Highly Diverse Human CD8+ TCR Repertoires to Immunodominant Viral AntigensQ33802568
Early therapy of vertical human immunodeficiency virus type 1 (HIV-1) infection: control of viral replication and absence of persistent HIV-1-specific immune responsesQ33808891
No one is naive: the significance of heterologous T-cell immunity.Q34136406
Cross-reactive influenza virus-specific CD8+ T cells contribute to lymphoproliferation in Epstein-Barr virus-associated infectious mononucleosisQ34147153
Heterologous immunity: immunopathology, autoimmunity and protection during viral infections.Q34159981
Deep sequencing of antiviral T-cell responses to HCMV and EBV in humans reveals a stable repertoire that is maintained for many years.Q34426420
Insulin needs after CD3-antibody therapy in new-onset type 1 diabetesQ34428346
Sustained complete responses in patients with lymphoma receiving autologous cytotoxic T lymphocytes targeting Epstein-Barr virus latent membrane proteinsQ35068768
Post-transplant lymphoproliferative disorder: a reviewQ35079593
Linking T-cell receptor sequence to functional phenotype at the single-cell levelQ35111823
Sharing of T cell receptors in antigen-specific responses is driven by convergent recombinationQ35214734
CD8+ TCR Bias and Immunodominance in HIV-1 InfectionQ35613273
Narrowing of human influenza A virus-specific T cell receptor α and β repertoires with increasing age.Q35640962
CD8 T cell cross-reactivity networks mediate heterologous immunity in human EBV and murine vaccinia virus infectionsQ35660783
The many important facets of T-cell repertoire diversityQ35709655
Selective expansion of high functional avidity memory CD8 T cell clonotypes during hepatitis C virus reinfection and clearanceQ36266416
Structural Basis for Clonal Diversity of the Public T Cell Response to a Dominant Human Cytomegalovirus EpitopeQ36323551
Dominant selection of an invariant T cell antigen receptor in response to persistent infection by Epstein-Barr virus.Q36364099
Memory of mice and men: CD8+ T-cell cross-reactivity and heterologous immunityQ36528984
The human T cell antigen receptor is encoded by variable, diversity, and joining gene segments that rearrange to generate a complete V geneQ36592410
The privacy of T cell memory to viruses.Q36627119
The need and challenges for development of an Epstein-Barr virus vaccineQ36795587
Frontiers in nephrology: heterologous immunity, T cell cross-reactivity, and alloreactivityQ36883338
Broad cross-reactive TCR repertoires recognizing dissimilar Epstein-Barr and influenza A virus epitopes.Q37082145
The molecular basis for public T-cell responses?Q37095250
Multiple glycines in TCR alpha-chains determine clonally diverse nature of human T cell memory to influenza A virusQ37105892
Reproducible selection of high avidity CD8+ T-cell clones following secondary acute virus infectionQ37544031
Maintenance of the EBV-specific CD8+ TCRαβ repertoire in immunosuppressed lung transplant recipientsQ37559771
Bias in the αβ T-cell repertoire: implications for disease pathogenesis and vaccinationQ37837483
T-cell therapy in the treatment of post-transplant lymphoproliferative diseaseQ38026758
The immunology of Epstein-Barr virus-induced diseaseQ38364278
Identifying specificity groups in the T cell receptor repertoireQ38715607
Antibodies to Epstein-Barr virus in Burkitt's lymphoma and control groupsQ38896500
Quantifiable predictive features define epitope-specific T cell receptor repertoiresQ40163819
Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8+ T cell epitope.Q40312408
MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.Q40325429
Defective T-cell control of Epstein-Barr virus infection in multiple sclerosisQ40333194
T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptideQ40368484
High resolution structures of highly bulged viral epitopes bound to major histocompatibility complex class I. Implications for T-cell receptor engagement and T-cell immunodominanceQ40431345
Disease etiology and diagnosis by TCR repertoire analysis goes viral.Q40464014
T-cell receptor V-region usage and antigen specificity. The cytochrome c model system.Q40465707
CD8(+) T-cell selection, function, and death in the primary immune response in vivoQ40735898
Frequent contribution of T cell clonotypes with public TCR features to the chronic response against a dominant EBV-derived epitope: application to direct detection of their molecular imprint on the human peripheral T cell repertoireQ40864361
The clonal composition of a peptide-specific oligoclonal CTL repertoire selected in response to persistent EBV infection is stable over time.Q41024103
T cell Receptor Alpha Variable 12-2 bias in the immunodominant response to Yellow fever virusQ41924958
Structural basis for clonal diversity of the human T cell response to a dominant influenza virus epitopeQ41933497
Immunosequencing identifies signatures of cytomegalovirus exposure history and HLA-mediated effects on the T cell repertoireQ41979810
Interpreting T-Cell Cross-reactivity through Structure: Implications for TCR-Based Cancer ImmunotherapyQ42372848
The role of production frequency in the sharing of simian immunodeficiency virus-specific CD8+ TCRs between macaquesQ42664373
Severity of Acute Infectious Mononucleosis Correlates with Cross-Reactive Influenza CD8 T-Cell Receptor Repertoires.Q47152645
Emerging Concepts in TCR Specificity: Rationalizing and (Maybe) Predicting OutcomesQ47782025
Unique influenza A cross-reactive memory CD8 T-cell receptor repertoire has a potential to protect against EBV seroconversion.Q50578821
A mechanism for TCR sharing between T cell subsets and individuals revealed by pyrosequencing.Q51017634
Naive T cell repertoire skewing in HLA-A2 individuals by a specialized rearrangement mechanism results in public memory clonotypes.Q51021454
Changing patterns of dominant TCR usage with maturation of an EBV-specific cytotoxic T cell response.Q52023617
Valpha and Vbeta public repertoires are highly conserved in terminal deoxynucleotidyl transferase-deficient mice.Q54688352
Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system.Q55061347
Single-Cell Approach to Influenza-Specific CD8+ T Cell Receptor Repertoires Across Different Age Groups, Tissues, and Following Influenza Virus Infection.Q55640449
Infectious MononucleosisQ56115612
Human T cell receptor occurrence patterns encode immune history, genetic background, and receptor specificityQ58697400
Isolation of cDNA clones encoding T cell-specific membrane-associated proteinsQ59067678
TCR -Chain Sharing in Human CD8+ T Cell Responses to Cytomegalovirus and EBVQ62673022
Differential kinetics and specificity of EBV-specific CD4+ and CD8+ T cells during primary infectionQ73020177
Understanding the drivers of MHC restriction of T cell receptorsQ88322419
OLGA: fast computation of generation probabilities of B- and T-cell receptor amino acid sequences and motifsQ91111240
CDR3α drives selection of the immunodominant Epstein Barr virus (EBV) BRLF1-specific CD8 T cell receptor repertoire in primary infectionQ91439648
P433issue2
P921main subjectEpstein–Barr virusQ6900
P577publication date2020-03-17
P1433published inmBioQ15817061
P1476titleEpstein-Barr Virus Epitope-Major Histocompatibility Complex Interaction Combined with Convergent Recombination Drives Selection of Diverse T Cell Receptor α and β Repertoires
P478volume11

Search more.