The effect of chronic cerebral hypoperfusion on the pathology of Alzheimer's disease: A positron emission tomography study in rats

scientific article published on 01 October 2019

The effect of chronic cerebral hypoperfusion on the pathology of Alzheimer's disease: A positron emission tomography study in rats is …
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scholarly articleQ13442814

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P356DOI10.1038/S41598-019-50681-4
P932PMC publication ID6773854
P698PubMed publication ID31575996

P50authorBong-Il SongQ90426462
P2093author name stringSang-Woo Lee
Kyoung Sook Won
Jae-Hyung Park
Hae Won Kim
Jeong-Ho Hong
Hyun Dong Ji
Jung-In Lee
Jung-Ah Jung
Kyung-Wha Yoon
P2860cites workTau pathology in Alzheimer disease and other tauopathiesQ22252520
Neuropathological stageing of Alzheimer-related changesQ27860862
Connectivity Disruption, Atrophy, and Hypometabolism within Posterior Cingulate Networks in Alzheimer's DiseaseQ28146452
Alzheimer's disease: the amyloid cascade hypothesisQ29547160
The influence of chronic cerebral hypoperfusion on cognitive function and amyloid β metabolism in APP overexpressing miceQ30477118
White matter lesions and glial activation in a novel mouse model of chronic cerebral hypoperfusionQ31119362
Resting hippocampal blood flow, spatial memory and agingQ33653749
Critically attained threshold of cerebral hypoperfusion: the CATCH hypothesis of Alzheimer's pathogenesisQ33950420
Pathophysiologic mechanisms of acute ischemic stroke: An overview with emphasis on therapeutic significance beyond thrombolysisQ34092793
Biphasic functional regulation in hippocampus of rat with chronic cerebral hypoperfusion induced by permanent occlusion of bilateral common carotid arteryQ34921939
Significance of white matter high intensity lesions as a predictor of stroke from arteriolosclerosisQ35467242
Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathologyQ35747757
Coevolution of white matter hyperintensities and cognition in the elderlyQ36117373
Cerebral White Matter Hypoperfusion Increases with Small-Vessel Disease Burden. Data From the Third International Stroke TrialQ36313426
Cardiovascular risk factors promote brain hypoperfusion leading to cognitive decline and dementiaQ36455581
Cerebral white matter lesions - associations with Aβ isoforms and amyloid PETQ36559869
Permanent, bilateral common carotid artery occlusion in the rat: a model for chronic cerebral hypoperfusion-related neurodegenerative diseasesQ36734195
Chronic cerebral hypoperfusion enhances Tau hyperphosphorylation and reduces autophagy in Alzheimer's disease miceQ36769022
Hippocampal CA1 apical neuropil atrophy and memory performance in Alzheimer's diseaseQ36917065
High-Fat-Diet Intake Enhances Cerebral Amyloid Angiopathy and Cognitive Impairment in a Mouse Model of Alzheimer's Disease, Independently of Metabolic DisordersQ37076115
Apoptotic mechanisms after cerebral ischemiaQ37381350
Type I interferon causes thrombotic microangiopathy by a dose-dependent toxic effect on the microvasculature.Q37508060
The global prevalence of dementia: a systematic review and metaanalysisQ38073027
Brain PET in suspected dementia: patterns of altered FDG metabolismQ38211221
Summary of the evidence on modifiable risk factors for cognitive decline and dementia: A population-based perspectiveQ38516632
ATP and brain functionQ38597443
Chronic intermittent hypoxia/reoxygenation facilitate amyloid-β generation in miceQ39109895
Non-invasive imaging and analysis of cerebral ischemia in living rats using positron emission tomography with 18F-FDG.Q41579555
Chronic brain hypoperfusion causes early glial activation and neuronal death, and subsequent long-term memory impairmentQ45219158
Whither the hippocampus? FDG-PET hippocampal hypometabolism in Alzheimer disease revisitedQ45234710
A semiautomated method for measuring brain infarct volume.Q45954002
Chronic cerebral hypoperfusion induces post-stroke dementia following acute ischemic stroke in rats.Q46085817
Reversal of age-related deficits in object recognition memory in rats with l-deprenyl.Q46527416
Chronic cerebral hypoperfusion and plasticity of the posterior cerebral artery following permanent bilateral common carotid artery occlusion.Q47160388
Beta-amyloid pathology in the entorhinal cortex of rats induces memory deficits: implications for Alzheimer's diseaseQ48168802
Brain lesions at autopsy in older Japanese-American men as related to cognitive impairment and dementia in the final years of life: a summary report from the Honolulu-Asia aging studyQ48491931
Chronic brain hypoperfusion due to multi-vessel extracranial atherosclerotic disease: a potentially reversible cause of cognitive impairmentQ48638148
Why are hippocampal CA1 neurons vulnerable but motor cortex neurons resistant to transient ischemia?Q48826937
Discrepancy in Expression of β-Secretase and Amyloid-β Protein Precursor in Alzheimer-Related Genes in the Rat Medial Temporal Lobe Cortex Following Transient Global Brain IschemiaQ48895685
Does posterior cingulate hypometabolism result from disconnection or local pathology across preclinical and clinical stages of Alzheimer's disease?Q50239485
Glucose Hypometabolism in Hippocampal Subdivisions in Alzheimer's Disease: A Pilot Study Using High-Resolution ¹⁸F-FDG PET and 7.0-T MRI.Q53074935
Association between white matter lesions and cerebral Aβ burdenQ58701393
Chronic cerebral hypoperfusion shifts the equilibrium of amyloid β oligomers to aggregation-prone species with higher molecular weightQ64103136
[Molecular mechanism and new protective strategy for ischemic white matter damages]Q85573795
Cognitive impairment and intracranial atherosclerotic stenosis in general populationQ88012966
Imaging the evolution and pathophysiology of Alzheimer diseaseQ91860896
P4510describes a project that usesImageJQ1659584
ImageQuantQ112270642
P433issue1
P921main subjectAlzheimer's diseaseQ11081
positron emission tomographyQ208376
P304page(s)14102
P577publication date2019-10-01
P1433published inScientific ReportsQ2261792
P1476titleThe effect of chronic cerebral hypoperfusion on the pathology of Alzheimer's disease: A positron emission tomography study in rats
P478volume9